N Ethyl 2 Acetylpyrrole
pyridine pyrrole pyrazine piperidine piperazine

N-Ethyl-2-Acetylpyrrole

    Specifications

    HS Code

    654075

    Chemical Formula C8H11NO
    Molar Mass 137.18 g/mol
    Appearance Liquid (usually)
    Boiling Point Approximately 220 - 225 °C
    Density Typically around 1.02 - 1.05 g/cm³
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Flash Point Caution, flammable; flash point in the range of 80 - 90 °C
    Odor Characteristic, somewhat pungent or aromatic odor

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    General Information
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    Frequently Asked Questions

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    What are the main uses of N-Ethyl-2-Acetylpyrrole?
    N-ethyl-2-acetylpyrrole is also an organic compound. It has a wide range of uses and is used in various fields such as chemical industry and medicine.
    In the field of chemical industry, it is often a key intermediate for the synthesis of many complex organic compounds. With its unique chemical structure, it can combine with other compounds through various chemical reactions, and then construct new substances with specific properties and functions. For example, in the field of materials science, this material can be used as a raw material to synthesize polymer materials with special electrical and optical properties, which can be used to manufacture advanced electronic components, optical devices, etc., to meet the needs of modern technology for high-performance materials.
    In the field of medicine, its utility cannot be underestimated. Because the pyrrole ring structure is common in many bioactive molecules, N-ethyl-2-acetyl pyrrole can be used as the core part of the lead compound. Pharmaceutical researchers can create drugs with specific pharmacological activities by chemical modification and structural optimization, such as antibacterial, anti-inflammatory, anti-tumor and other drugs. Taking antibacterial drugs as an example, by precisely adjusting their structure, they can improve the inhibition or killing ability of specific bacteria and escort human health.
    In addition, in the basic research of organic synthetic chemistry, N-ethyl-2-acetyl pyrrole is also an important research object. By exploring the chemical reaction mechanisms and reaction conditions involved, scholars can gain a deeper understanding of the nature of organic reactions, contribute to the development of organic synthesis methodologies, and help develop more efficient and green organic synthesis pathways.
    What are the physical properties of N-Ethyl-2-Acetylpyrrole?
    N-ethyl-2-acetylpyrrole is one of the organic compounds. It has specific physical properties and is related to many fields of chemical industry and scientific research.
    Looking at its physical properties, it is mostly in a liquid state at room temperature and pressure. Its color may be nearly colorless, or slightly yellow, clear and transparent, with a special smell. Although it is not pungent, it also has a unique smell, which can be identified by the sense of smell under specific conditions.
    As for the boiling point, it is about a certain temperature range. The value of this boiling point varies according to its purity and the ambient pressure. Usually under standard pressure conditions, the number of boiling points can be used as a reference for separating and purifying this compound during chemical operations, in order to control the reaction process and product purity.
    Furthermore, the melting point is also an important physical property. The determination of the melting point helps to determine the purity of the substance. The melting point of the pure product is relatively fixed. If it contains impurities, the melting point may drop, and the melting range will also become wider.
    In terms of solubility, N-ethyl-2-acetyl pyrrole exhibits different solubility characteristics in organic solvents. It is soluble in common organic solvents such as ethanol, ether, etc. This solubility property is crucial in organic synthesis reactions. It can be used as a reaction medium to make the reactants better contact and mix, and promote the progress of the reaction. It can also be separated and purified by the difference in solubility to achieve the effect of separation.
    In addition, density is also one of the factors to consider its physical properties. Its density value is of great significance for the material measurement and pipeline transportation of chemical production, ensuring the accuracy and safety of the production process.
    In short, the physical properties of N-ethyl-2-acetyl pyrrole are important factors to consider in the fields of chemical production, organic synthesis and scientific research exploration, helping researchers and producers to better control this substance and play its role.
    Is N-Ethyl-2-Acetylpyrrole chemically stable?
    If N-Ethyl-2-Acetylpyrrole is present, there is also a compound. The determination of its chemical properties is uncertain, and it needs to be polyterminal.
    This compound has pyrrole, pyrrole, and its sub-cloud density is specific, resulting in low reactivity. The concatenation of N-ethyl groups, due to the inference effect of ethyl groups, has a slight impact on the sub-cloud density of pyrrole, which can make the sub-cloud density of pyrrole slightly increase. In some substitution reactions, it may be more likely to cause reactions.
    However, the presence of 2-acetyl group, which is an adsorbent, can reduce the density of the sub-cloud of Pyrrole, especially in its shape and position. The interaction of this sub-effect, N-Ethyl-2-Acetylpyrrole, shows different activities under different anti-effects.
    In normal and special effects, N-Ethyl-2-Acetylpyrrole is determined. However, if it encounters an acid, its chemical properties are uncertain due to the weak performance of pyrrole, and it is easy to be nucleated, or the cracking of pyrrole. If it is oxidized, the α-acetyl group is acidic to a certain extent, or it can generate catalyzed phase inversion, such as enolization, inversion, etc., which also indicates that its chemical properties are active in this case.
    In addition, if it encounters oxidation, pyrrole is easily oxidized, causing the chemical properties of the compound to be broken and exhibiting uncertainty. In some cases, the isofunctionalities of the acetyl group can be oxidized, which also shows that the chemical properties of the N-Ethyl-2-Acetylpyrrole can be changed due to the inversion of the inversion.
    In other words, the chemical properties of N-Ethyl-2-Acetylpyrrole are determined or not, and the environment of the end, the contact and the inversion can not be generalized.
    What are N-Ethyl-2-Acetylpyrrole synthesis methods?
    There are several methods for synthesizing N-ethyl-2-acetyl pyrrole in the past. First, 2-acetyl pyrrole is used as the starting material to react with haloethane in an alkaline environment. For example, dissolve 2-acetyl pyrrole in a suitable organic solvent, such as N, N-dimethylformamide (DMF), then add potassium carbonate and other bases, stir well, and then slowly add haloethane dropwise. In this process, the halogen atom of haloethane is active. Under the action of alkali, it can undergo nucleophilic substitution reaction with the nitrogen atom of 2-acetyl pyrrole, and then form N-ethyl-2-acetyl pyrrole. After the reaction is completed, the pure product can be obtained through extraction, washing, drying, distillation and other steps.
    Second, pyrrole is used as the starting material. Shilling pyrrole and acetylation reagents, such as acetyl chloride or acetic anhydride, under the catalysis of catalysts, such as anhydrous aluminum trichloride, carry out acetylation reaction to obtain 2-acetyl pyrrole. Subsequently, the obtained 2-acetyl pyrrole was synthesized by nucleophilic substitution reaction according to the above method of reacting with haloethane to synthesize N-ethyl-2-acetyl pyrrole. Although this path is slightly complicated, the raw material pyrrole is easy to obtain, and the reaction conditions of each step are relatively mild and easy to control.
    Third, there is also a method of reacting 2-haloacetyl pyrrole with ethylamine. The halogen atom of 2-haloacetyl pyrrole is quite active and can undergo nucleophilic substitution with ethylamine. The reaction can occur by dissolving the two in a suitable solvent, such as ethanol, heating and stirring. After the reaction is completed, N-ethyl-2-acetyl pyrrole can also be obtained after separation and purification. This method is simple, but the preparation of 2-haloacetyl pyrrole may require special steps, and the amount of ethylamine in the reaction, the reaction temperature and other factors have an impact on the yield and purity of the product, which must be carefully regulated.
    N-Ethyl-2-Acetylpyrrole What are the precautions in storage and transportation?
    N-ethyl-2-acetylpyrrole is an organic compound. During storage and transportation, many matters need to be paid attention to.
    First storage environment. This compound should be stored in a cool, dry and well-ventilated place. Because it is cool, it can avoid chemical changes caused by excessive temperature, drying can prevent it from moisture hydrolysis or reaction with water vapor, and good ventilation can prevent the accumulation of harmful gases. Do not place it in direct sunlight. The energy of sunlight may cause luminescent chemical reactions to cause it to deteriorate.
    Second words packaging material. Suitable packaging must be used, usually sealed glass or plastic bottles to ensure tight leakage. Glass bottles can provide stable protection, plastic bottles need to be resistant to corrosion of this compound. The outside of the package should be clearly marked with its product name, nature, danger warning and other information for identification and disposal.
    Furthermore, when transporting, relevant regulations must be followed. Transportation vehicles need to be equipped with corresponding protection and emergency equipment to prevent accidents such as leakage. If transported with other chemicals, pay attention to their compatibility, and must not be mixed with those who can react violently with them, such as strong oxidants, strong acids and alkalis, etc., otherwise there may be explosions, fires and other dangerous situations.
    Transportation and storage personnel also need to undergo professional training, familiar with the characteristics of this compound and emergency treatment methods. Once a leak occurs, effective measures can be taken immediately, such as evacuating the crowd, sealing the site, and adsorbing and cleaning with suitable materials, to minimize the harm. In this way, the N-ethyl-2-acetyl pyrrole is safely stored and transported.