N-Benzenesulphonylpyrrole

N-benzenesulfonyl pyrrole is also an organic compound. It has a wide range of uses and is often a key intermediate in the field of organic synthesis. Due to its unique structure, it can be derived from various complex and functional compounds through various chemical reactions.
In the field of pharmaceutical chemistry, N-benzenesulfonyl pyrrole may participate in the creation of new drugs. Because it can interact with specific targets in organisms, or can exhibit pharmacological activities, such as antibacterial, anti-inflammatory, anti-tumor and other effects, it contributes to the cause of human health.
In the field of materials science, this compound can also be used. After appropriate modification and polymerization, materials with special properties can be prepared, such as optical materials, electrical materials, etc. In the process of molecular self-assembly, by virtue of its own structural characteristics, or it can build an orderly and stable microstructure, endowing the material with unique optical and electrical properties, thus expanding the application range of materials.
In addition, in the fine chemical industry, N-benzenesulfonyl pyrrole can be used as a raw material for the synthesis of special chemicals, used for the preparation of fine chemicals such as fragrances and dyes, to improve product quality and performance, and to meet the diverse needs of the market. In summary, N-benzenesulfonyl pyrrole has been widely used in organic synthesis, medicinal chemistry, materials science and fine chemistry because of its unique structure and reactivity.

N - Benzenesulphonylpyrrole is one of the organic compounds. Its physical properties are of great interest and are described below.
Looking at its appearance, at room temperature, it often takes the shape of a solid state. Most of them are white to white crystalline powders, just like the thin snow that falls in the early winter. They are delicate and pure. When placed in light, they flicker slightly, like fine jade chips. This form is easy to store and use, and provides convenience in many chemical operations.
When it comes to melting point, after precise determination, the melting point of N - Benzenesulphonylpyrrole is within a specific range. This melting point characteristic plays an important role in the identification and purity judgment of compounds. If the purity is extremely high, its melting point will approach the established standard value, just like a precise pointer pointing to a specific scale; if it contains impurities, the melting point may be offset, and the melting range will also become wider, which is the key to distinguish the advantages and disadvantages of purity.
In terms of solubility, this compound exhibits unique properties in organic solvents. In halogenated hydrocarbon solvents such as dichloromethane and chloroform, it is quite soluble, just like fish entering water and dissolving leisurely. In common alcohols such as ethanol, it also has some solubility, but the solubility is slightly inferior to that of halogenated hydrocarbons. However, in water, its solubility is very small, just like the barrier between oil and water, and it is difficult to blend. This solubility characteristic plays a key role in the separation, purification and construction of reaction systems of compounds.
As for the density, although it is not as heavy as a metal, it also has its specific value. The existence of its density affects the distribution and behavior of the compound in the mixed system, and is of great significance in the control of the material ratio and reaction process in chemical production. The physical properties of
N-Benzenesulphonylpyrrole, from appearance, melting point, solubility to density, are the cornerstones of chemical research and application, providing an indispensable basis for many fields such as organic synthesis and drug development.

N-Benzenesulphonylpyrrole is an organic compound, and its chemical properties are very interesting. Let me describe in detail.
In this compound, benzenesulfonyl is connected to the pyrrole ring. The pyrrole ring has certain aromatic properties, while the benzenesulfonyl group is active. From the perspective of reactivity, the sulfur atom in the benzenesulfonyl group has positive electricity and can participate in the reaction as an electrophilic center. For example, when encountering nucleophiles, the nucleophiles are prone to attack the sulfur atom, causing the benzenesulfonyl group to partially replace and other reactions.
Furthermore, the nitrogen atom on the pyrrole ring has a pair of lone pairs of electrons, which can affect the distribution of the entire molecular electron cloud. The electron cloud density of pyrrole ring increases because of the solitary pair electrons participating in the ring conjugation system, so the pyrrole ring is more prone to electrophilic substitution. However, due to the electron-absorbing effect of benzenesulfonyl groups in N-Benzenesulphonylpyrrole, the electron cloud density of pyrrole ring will be reduced, and the electrophilic substitution activity is slightly reduced compared with pyrrole itself.
In addition, this compound is quite sensitive to acid-base environment. Under acidic conditions, pyrrole ring nitrogen atoms may protonate, changing the electronic structure and reactivity of the molecule; in alkaline environments, benzenesulfonyl groups may undergo reactions such as hydrolysis, resulting in molecular structure changes.
Because its molecules contain benzene rings and pyrrole rings, typical reactions of aromatic compounds such as halogenation, nitrification, and sulfonation can occur. If the reaction conditions are appropriate, the corresponding substituents can be introduced at specific positions of the benzene ring or pyrrole ring to synthesize organic compounds with more complex structures.
In short, N-Benzenesulphonylpyrrole has rich chemical properties and has important potential application value in the field of organic synthesis. Through in-depth investigation of its properties, many organic compounds can be effectively synthesized and converted.

There are many different methods for synthesizing N-benzenesulfonyl pyrrole. One method is to take pyrrole first and treat it with an alkali agent to generate the corresponding pyrrole anion. Due to its nucleophilicity, it can undergo nucleophilic substitution reaction with benzenesulfonyl chloride. Mix the two in a suitable solvent, such as anhydrous dichloromethane, and react at low temperature and stirring. Among them, alkalis are often used as strong bases such as sodium hydride and potassium tert-butyl alcohol, which can quickly convert pyrrole into pyrrole anion, and then react efficiently with benzenesulfonyl chloride to obtain N-benzenesulfonyl pyrrole.
Another method can use transition metal catalysis. Using metals such as palladium and copper as catalysts, with the assistance of ligands, pyrrole is reacted with benzene sulfonylation reagents. For example, using cuprous iodide as a catalyst and 1,10-phenanthroline as a ligand, the reaction is in a suitable base agent and solvent. Potassium carbonate and other alkali agents can be selected, and N, N-dimethylformamide (DMF) can be selected as a solvent. This system can promote the bonding of pyrrole nitrogen atoms with benzene sulfonyl groups, so as to achieve the synthesis of N-benzene sulfonyl pyrrole.
In addition, pyrrole derivatives can also be considered as starting materials through functional group transformation. First, the specific position of pyrrole is introduced into the transformable group, and then the group is converted into benzenesulfonyl group through a series of reactions, and finally N-benzenesulfonyl pyrrole is obtained. However, this path is relatively complex, and the reaction steps and conditions need to be carefully designed to ensure the selectivity and yield of the reaction.
Each method has its own advantages and disadvantages. According to the actual situation, such as the availability of raw materials, the ease of control of reaction conditions, and the requirements of product purity, etc., it is necessary to choose the appropriate one and use it to efficiently synthesize N-benzenesulfonyl pyrrole.

Today there is a question, what is the price of N-Benzenesulphonylpyrrole in the market? This is a fine chemical, and its price varies depending on quality, supply and demand, purchase quantity and sales place. If the quality is good, the supply is less and the demand is more, the price will be high; if the purchase volume is huge, the price may be compromised.
In the chemical raw material market, the quality is ordinary, or between hundreds of yuan per kilogram. However, if you want high-purity products, used in scientific research or high-end manufacturing, the price should be doubled, or tens of yuan per gram.
Purchased from large chemical suppliers, the price may be affordable due to wide supply and cost control; at small reagents, the price is often higher due to small quantity and high operating costs. < Br >
To confirm the price, it is advisable to consult chemical raw material suppliers, reagent companies, or visit chemical product trading platforms to compare their quotations to obtain a near-real price.