N-Benzenesulfonylpyrrole

N-Benzenesulfonylpyrrole, or N-benzenesulfonyl pyrrole, has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Due to its unique structure, it can participate in many chemical reactions to build complex organic molecular structures.
For example, in the field of medicinal chemistry, N-benzenesulfonyl pyrrole is used as the starting material, and compounds with specific biological activities can be synthesized through a series of reactions. These compounds may show potential therapeutic effects on certain diseases, providing an important direction for the development of new drugs.
It is also useful in the field of materials science. With the help of specific chemical reactions, it can be introduced into the structure of polymer materials to improve the properties of materials. Such as improving the stability and optical properties of materials, so as to meet the special needs of materials in different fields.
In addition, in organic catalytic reactions, N-benzenesulfonyl pyrrole can play a unique catalytic role by virtue of its structural characteristics, promoting the efficient progress of the reaction, and can improve the selectivity and yield of the reaction, which is of great significance for the optimization of organic synthesis reactions. In short, N-benzenesulfonyl pyrrole plays an indispensable role in many chemical-related fields, promoting the development and progress of various fields.

N-benzenesulfonyl pyrrole is one of the organic compounds. Its physical properties, first words appearance, under normal conditions, often white to pale yellow crystalline powder, fine in appearance, or slightly shiny under light.
When it comes to the melting point, it is about a specific temperature range. This temperature range is crucial for its physical state transformation. Due to the characteristics of the melting point, it can be a key indicator in the identification and purification of this compound. The exact value of its melting point is roughly within a certain range according to different experimental conditions or slight differences.
In terms of solubility, it has a certain solubility in common organic solvents, such as ethanol, chloroform, etc. Ethanol is a commonly used organic solvent, and N-benzenesulfonyl pyrrole can be moderately dissolved in it to form a uniform solution. In water, its solubility is poor, due to the molecular structure characteristics of the compound, the interaction between it and water molecules is weak, so it is difficult to dissolve in water.
Looking at its density, although it is not very easy to observe, its value can be obtained under specific conditions. This value reflects the mass of its unit volume. It is of reference significance for the measurement and operation of materials in chemical production and related research.
In addition, its volatility is very small, and it is not easy to disperse in the air under normal temperature and pressure. This characteristic makes it relatively stable during storage and use, reducing losses and safety hazards caused by volatilization. All these physical properties are related to each other, together describing the characteristics of N-benzenesulfonyl pyrrole, laying the foundation for its application in many fields such as organic synthesis and drug development.

N-Benzenesulfonylpyrrole is an organic compound with unique chemical properties. Its structure contains benzenesulfonyl groups and pyrrole rings, which endow it with various chemical activities.
In terms of reactivity, pyrrole rings have electron-rich properties and are prone to electrophilic substitution reactions. The presence of benzenesulfonyl groups affects the check point and activity of the reaction. For example, electrophilic reagents tend to attack specific locations on the pyrrole ring, because the electron-absorbing effect of benzenesulfonyl groups alters the electron cloud distribution on the ring.
In terms of solubility, the compound has poor solubility in water due to the presence of hydrophobic parts such as benzene rings and pyrrole rings. However, in organic solvents such as dichloromethane and chloroform, due to the interaction between molecules, it has good solubility, which is of great significance for the separation step of organic synthesis.
In terms of stability, N-Benzenesulfonylpyrrole is relatively stable under conventional conditions. However, in the case of strong acid and strong base, its structure may change. In the strong base environment, the pyrrole ring nitrogen atom may be deprotonated, which may lead to subsequent reactions; under strong acid conditions, benzenesulfonyl or pyrrole ring may also undergo protonation and other reactions.
In terms of thermal stability, moderate heating of the compound can maintain stability, but at high temperature or decomposition, the decomposition products such as sulfur dioxide are produced. Its specific decomposition temperature is affected by structure and environment. In terms of spectral properties, the characteristic absorption peaks of benzene ring, pyrrole ring and benzenesulfonyl group can be observed through infrared spectroscopy. For example, the stretching vibration peak of benzene ring C = C double bond, pyrrole ring N-H stretching vibration peak, and benzenesulfonyl S = O double bond strong absorption peak. In nuclear magnetic resonance spectroscopy, hydrogen atoms at different positions show unique chemical shifts due to differences in chemical environment, which provides a strong basis for structure identification. The chemical properties of
N-Benzenesulfonylpyrrole are determined by their structure, which is of great significance in organic synthesis, medicinal chemistry and other fields. By grasping their properties, the design and synthesis of related compounds can be better realized.

To prepare N-benzenesulfonyl pyrrole, there are two common methods. The first is to use pyrrole and benzenesulfonyl chloride as raw materials and react in an alkaline environment. In this reaction, the base can take hydrogen from pyrrole nitrogen, making it negative ion state, the activity is greatly increased, and then nucleophilic substitution reaction occurs with benzenesulfonyl chloride to obtain the target product. Commonly selected bases include organic bases such as pyridine and triethylamine, or inorganic bases such as sodium hydroxide and potassium hydroxide. However, when reacting, it is necessary to pay attention to the amount of base and the reaction temperature to prevent excessive reaction from increasing by-products.
The second method is to react with benzenesulfonylation reagent with pyrrole derivatives. For example, the pyrrole is properly modified first, and the group that is conducive to the reaction is introduced, and then it interacts with the benzene sulfonylation reagent. This approach can improve the selectivity and yield of the reaction. However, the preparation of pyrrole derivatives may require multiple steps of the reaction, and the process is more complicated. It is necessary to carefully plan the reaction route and strictly control the reaction conditions of each step.
These two methods have their own advantages and disadvantages. In the actual synthesis, the appropriate synthesis method should be carefully selected according to the availability of raw materials, the controllability of the reaction conditions, and the purity requirements of the target product.

I don't know what the price range of N - Benzenesulfonylpyrrole is in the market. This is a rather professional chemical substance, and its price is affected by many factors.
First, the purity has a huge impact. If the purity is extremely high, it is almost flawless, and the price will be high; if the purity is slightly inferior, it contains some impurities, and the price may drop.
Second, the market supply and demand are of great importance. If the demand is strong, and the supply is scarce, the price will rise; if the supply exceeds the demand, the merchant will sell its goods or reduce the price.
Third, the difficulty of the production process also plays a role. If the production requires complex and ingenious methods, the cost will increase, and the price will rise; if the process is relatively simple, the cost is controllable, and the price may be close to the people.
Fourth, the source and origin are different, and the price may be different. For overseas importers, or due to transportation, tariffs, etc., the price is different from that of local products.
However, I have not seen detailed price information, so it is difficult to determine its price range. For accurate prices, you can consult chemical reagent suppliers, chemical product trading platforms, or those who specialize in the industry. They may be able to tell you the price range of N-Benzenesulfonylpyrrole according to the current market conditions.