N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide

N- [2- (diethylamino) ethyl] -2,4-dimethyl-1H-pyrrole-3-formamide has a wide range of uses. In the field of medicine, this compound may have unique pharmacological activities and can be used as a lead compound to develop new drugs. Due to the properties of pyrrole structure and amide groups, it may interact with specific biological targets, such as proteins that act on cell signaling pathways, regulate cell physiological activities, and is expected to be used in the treatment of specific diseases, such as certain inflammatory diseases or neurological disorders.
In materials science, it may be able to participate in the preparation of special functional materials. With different groups in the molecule, ordered structural materials can be chemically modified, such as the preparation of materials with specific orientation or self-assembly characteristics, which may have applications in the field of nanotechnology, such as the construction of nano-scale ordered array structures for sensor devices to improve the recognition and detection performance of sensors for specific substances.
Furthermore, in organic synthesis chemistry, the compound may be a key intermediate. Because of its multi-activity check point in the structure, it can be further derived from a variety of organic reactions, synthesizing organic compounds with more complex structures and more diverse functions, expanding new paths for organic synthesis chemistry and helping to create more novel and valuable organic molecules.

This is N- [2- (diethylamino) ethyl] -2,4-dimethyl-1H-pyrrole-3-formamide, which is an organic compound. Looking at its structure, it contains a pyrrole ring, which is common in many bioactive molecules, or endows the compound with specific pharmacological activity.
In terms of physical properties, most of them are solid, due to the interaction between molecules such as van der Waals force and hydrogen bonding. As for solubility, because it contains polar amide groups and diethylamino groups, it may have some solubility in polar solvents such as ethanol and methanol, but it may have poor solubility in non-polar solvents such as n-hexane. < Br >
When it comes to chemical properties, the reactivity of amide groups cannot be ignored. Hydrolysis reactions can occur. Under acidic or basic conditions, amide bonds are broken to form corresponding carboxylic acids and amines. At the same time, pyrrole rings also have certain reactivity, and electrophilic substitution reactions can occur due to their high electron cloud density on the ring. In addition, the nitrogen atom of diethylamino group has solitary pair electrons, which can participate in the reaction as a nucleophilic reagent, and undergo nucleophilic substitution reactions with electrophilic reagents such as halogenated hydrocarbons to form new nitrogen-containing compounds.
This compound is rich in chemical properties and may have potential application value in the fields of organic synthesis and drug development.

To prepare N - [2 - (diethylamino) ethyl] - 2,4 - dimethyl - 1H - pyrrole - 3 - formamide, there are many methods, which can be selected according to different raw materials and conditions.
First, start with 2,4 - dimethyl - 1H - pyrrole - 3 - formic acid. First, it is co-heated with sulfuryl chloride to obtain 2,4 - dimethyl - 1H - pyrrole - 3 - formyl chloride. This step is a common method of carboxyl transacid chloride. Sulfuryl chloride is active and can promote the rapid reaction. Then, 2 - (diethylamino) ethylamine is dissolved in an appropriate solvent, such as dichloromethane, and the above-mentioned acid chloride is added dropwise at low temperature. After aminolysis reaction, the target product can be obtained. The raw materials are easy to purchase, the reaction steps are clear, and the conditions are mild. However, it is necessary to pay attention to the high activity of acid chloride, and the operation should avoid water vapor.
Second, 2,4-dimethylpyrrole is used as a group. First, the pyrrole ring is formylated, and the Wilsmeier-Hack reaction is commonly used. The formyl group is introduced at the 3 position of pyrrole with N, N-dimethylformamide and phosphorus oxychloride as reagents Subsequently, the formylation product is condensed with 2 - (diethylamino) ethylamine, and the imine intermediate can be reduced to the target amide by catalytic hydrogenation or by reducing agents such as sodium borohydride. This method has a little more steps, but it can flexibly regulate the modification of pyrrole rings, which has advantages for specific structural requirements.
Or, start with a suitable halogen. For example, 2 - (diethylamino) ethyl halide reacts with 2,4 - dimethyl - 1H - pyrrole - 3 - formamide in the presence of a base. The base can bind the acid and promote nucleophilic substitution to obtain the target. The key to this is the choice of halide activity and base. Although active high halide is easy to react, it may cause side reactions; the strength of the base also affects the reaction process and product purity.
All synthesis methods have their own advantages and disadvantages. The actual operation needs to be comprehensively weighed according to the availability of raw materials, cost, yield and purity requirements, and the optimal route is selected to prepare N - [2 - (diethylamino) ethyl] -2,4 - dimethyl - 1H - pyrrole - 3 - formamide.

This is N - [2 - (diethylamino) ethyl] - 2,4 - dimethyl - 1H - pyrrole - 3 - formamide. To investigate its safety, it is necessary to explore it in detail with multiple evidence.
Observe this thing, or under specific experimental scenarios, it has been strictly tested to show its effect on organisms. If animals are used as models, observe whether it has any abnormalities in physiological function and behavioral characteristics after ingestion and exposure. If after many and diverse animal experiments, no significant adverse effects are found, such as no organ damage, no behavioral disorders, no obstacles to reproductive development, etc., it can be initially judged to be safe in the animal layer.
However, there are differences in animal and human physiology. Therefore, it is also necessary to observe its situation in human clinical trials. In small-scale human trials, the reactions of the subjects are carefully observed, such as whether there are allergies, discomfort, and changes in biochemical indicators. If the small-scale trials are stable, then expand the scale to obtain a more reliable conclusion.
And its safety is also related to the route of use, dosage and frequency. If it is used in medicine, it must be treated under strict regulations and according to the appropriate dose to ensure safety. If it is used in excess, even if it is originally safe, it may have adverse consequences. And if it is used in other ways, such as industrial production assistance, its potential impact on the environment and contact personnel should not be ignored. It is necessary to check its degradation in the environment, whether there is any risk of pollution, and whether the health status of long-term contact personnel has changed.
In summary, only the name of this substance is known, and its safety cannot be determined. It must be supported by multiple experiments and data, and carefully considered in different scenarios before its safety can be determined.

This is an organic compound, called N- [2 - (diethylamino) ethyl] -2, 4 - dimethyl - 1H - pyrrole - 3 - formamide. Involving its related derivatives, it is mentioned in the books that many variants of such compounds may be derived due to the change of specific groups in the molecular structure.
Looking at its structure, the change of the substituents on the pyrrole ring may lead to other derivatives. For example, at 2,4 - dimethyl, if other alkyl and aryl groups are substituted, new pyrrole derivatives can be obtained. The [2- (diethylamino) ethyl] part attached to the amide group can also create different derivatives if the carbon chain length and branching status of the alkyl group attached to the amino group are changed.
Furthermore, at other checking points of the pyrrole ring, such as the introduction of halogen atoms, nitro groups, hydroxyl groups and other functional groups at the 5-position, new derivatives can be prepared by organic synthesis. Such derivatization operations, or due to the electronic effects and spatial effects of different functional groups, make the new compounds exhibit unique physical, chemical and biological activities.
And because the compound contains nitrogen atoms, or can be complexed with metal ions to form metal complex derivatives, which can be used in catalysis, materials science and other fields or have other uses. This is all based on the principles of organic chemistry and past synthesis experience, but the specific synthesis and property exploration still need to be confirmed by experiments.