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What is the chemical structure of METHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE
Methyl-6H-thiopheno [2,3-b] pyrrole-5-carboxylic acid ester, this is the name of an organic compound. To know its chemical structure, follow the principles of organic chemistry.
thiopheno [2,3-b] pyrrole, this is the parent nuclear structure. Thiophene is a sulfur-containing five-membered heterocyclic ring with aromatic properties. Pyrrole is also a five-membered heterocyclic ring with nitrogen atoms in the ring. The two fuse to form thiopheno [2,3-b] pyrrole. In this fused ring system, the 2,3 positions of thiophene are connected to the ring of pyrrole, forming a unique ring structure.
As for "6H", this refers to the position of a specific hydrogen atom. The number "6" indicates the atomic position, and "H" indicates the hydrogen atom, that is, there is a hydrogen atom at the 6th position.
In addition, "5-carboxylate" indicates that there is a carboxylate functional group at the 5th position of the parent nucleus structure. The carboxylate is the group obtained by replacing the hydroxyl group of the carboxyl group (-COOH) with an alkoxy group (-OR). In this compound, the carboxylic acid ester attached to the 5th position is specifically a methyl ester group (-COOCH), because the word "methyl" is at the beginning of the name, which indicates that the alkoxy part of the ester group is methyl.
In summary, the chemical structure of methyl-6H-thiopheno [2,3-b] pyrrole-5-carboxylic acid ester is an organic compound with thiopheno [2,3-b] pyrrole as the parent nucleus, hydrogen atom at 6 position, and methyl ester group at 5 position.
What are the main uses of METHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE
Methyl-6H-thiopheno [2,3-b] pyrrole-5-carboxylic acid ester, this substance has a wide range of uses and is useful in the fields of medicine, materials and chemical industry.
In the field of medicine, it is an important intermediate in organic synthesis and can prepare a variety of bioactive compounds. By modifying its structure, drug molecules with specific pharmacological activities can be obtained, such as antibacterial, anti-inflammatory, anti-tumor, etc. Based on it, through complex organic reactions, new chemical entities may be obtained, opening up new paths for the development of new drugs and helping to overcome many difficult diseases.
In the field of materials, due to its unique structure and electronic properties, it can be used to prepare functional materials. For example, in the field of organic optoelectronic materials, it can be used as a luminescent material or an electron transport material for organic Light Emitting Diode (OLED) to improve its luminous efficiency and stability, so that the display device is clearer and more energy-efficient. In the field of sensor materials, it can be used to selectively identify and respond to specific substances to make high-sensitivity, high-selectivity sensors for detecting environmental pollutants, biomolecules, etc.
In the chemical industry, it provides key starting materials for the synthesis of complex organic compounds. Through various reaction paths, it can synthesize a variety of chemicals with novel structures and unique properties. In the manufacture of fine chemical products, it can be used as an important component to improve product performance and quality, such as fragrances, coatings, additives and other fine chemicals. With its unique chemical structure, this compound plays an important role in many fields, promoting technological innovation and development in various fields.
What are the synthesis methods of METHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE
The synthesis of methyl-6H-thiopheno [2,3-b] pyrrole-5-carboxylate is the key to chemical preparation. To obtain this compound, there are various common approaches.
First, it can be obtained from raw materials containing thiophene and pyrrole structures through a multi-step reaction. Initially, suitable thiophene derivatives and pyrrole derivatives are selected, and under specific reaction conditions, the condensation reaction occurs. This process requires careful regulation of reaction temperature, time, and reactant ratio. For example, mix the two in a precise molar ratio, place them in an organic solvent, such as anhydrous ethyl ether or toluene, and add an appropriate catalyst, such as Lewis acid, such as aluminum trichloride. Heating and refluxing for several hours prompts the condensation of the two to form a preliminary intermediate.
Then, carboxylation is carried out for the intermediate. Usually carbon dioxide is used as the carboxyl source. Under basic conditions, such as sodium hydride or potassium tert-butyl alcohol as a base, carbon dioxide is introduced into the reaction system at a low temperature environment, such as minus tens of degrees Celsius. This step needs to be closely monitored to prevent side reactions. After the carboxyl group is successfully introduced, the esterification reaction is carried out. Methanol and suitable catalysts, such as concentrated sulfuric acid or p-toluenesulfonic acid, are selected and refluxed for several hours to obtain methyl-6H-thiopheno [2,3-b] pyrrole-5-carboxylate. < Br >
Second, it can also be achieved by the strategy of constructing thiophene-pyrrole rings. First, a simple sulfur-containing compound and a nitrogen-containing compound are used as starting materials to construct a thiophene-pyrrole skeleton through cyclization. Then, according to the above-mentioned similar carboxylation and esterification methods, the synthesis of the target product is gradually completed.
The key to the synthesis of this compound lies in the precise control of the reaction conditions at each step, as well as the fine separation and purification of the intermediate, in order to improve the purity and yield of the product.
What are the physical and chemical properties of METHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE
Methyl-6H-thiopheno [2,3-b] pyrrole-5-carboxylic acid ester is one of the organic compounds. Its physical and chemical properties are worth exploring.
When it comes to physical properties, this compound is mostly in a solid state at room temperature and pressure, but the specific state also depends on its purity and surrounding environmental conditions. The determination of its melting point is very important for material identification and purity determination. Unfortunately, there is no detailed record of the exact melting point. Due to factors such as synthesis methods and impurity content, the melting point is greatly affected.
Looking at its chemical properties, the molecular structure contains a heterocyclic structure of thiopheno-pyrrole, which gives it unique electronic properties. The conjugated system in the ring makes the compound have a certain electron delocalization, which affects its chemical reactivity. Its carboxyl ester functional group has active chemical properties and can participate in many chemical reactions. For example, under basic conditions, hydrolysis is prone to occur to generate corresponding carboxylic acids and alcohols. This hydrolysis reaction can provide a key intermediate for subsequent organic synthesis. It can also undergo nucleophilic substitution reactions with nucleophiles. Because the carbonyl carbon in the ester group has a certain positive electricity, it is vulnerable to attack by nucleophiles. The thiophene ring and pyrrole ring of this compound can also participate in the aromatic electrophilic substitution reaction. Because of its electron-rich aromatic system, it is attractive to electrophilic reagents, and substituents can be introduced at specific positions on the ring, thereby expanding the types of its derived compounds. There is great potential for applications in pharmaceutical chemistry, materials science and other fields. In short, the physicochemical properties of methyl-6H-thiopheno [2,3-b] pyrrole-5-carboxylate lay the foundation for its application in organic synthesis and related fields.
What is the price of METHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE in the market?
Today I have a question, what is the price status of "METHYL + 6H - THIENO [2,3 - B] PYRROLE - 5 - CARBOXYLATE" in the market. This is a chemical product. As far as I know, the market is changeable, and this product may vary in price due to its use, purity, and supply and demand.
In the chemical industry market, if it is a common product, the supply is sufficient, and its price may be relatively easy. However, if this product is a rare raw material, it is indispensable for specific chemical processes and pharmaceutical research and development, and the output is limited. If it is sought, the price will be high.
Also, its purity is also the key to the price. For those with high purity, it is difficult to prepare, the cost is quite high, and the price is higher than that of ordinary purity. However, I have not personally involved in the transaction of this product, so it is difficult to determine the price. To know the details, you should consult the merchants of chemical materials, the brokers involved in this industry, or check the platforms and information of chemical transactions to get the real price in the market.