Methyl 2 5 Dioxo 2 5 Dihydro 1h Pyrrole 1 Carboxylate
pyridine pyrrole pyrazine piperidine piperazine

Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate

    Specifications

    HS Code

    361707

    Chemical Formula C6H5NO4
    Molar Mass 155.11 g/mol
    Appearance Solid
    Color White to off - white
    Odor Odorless
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane
    Melting Point 124 - 126 °C
    Boiling Point Decomposes before boiling
    Density Approx. 1.44 g/cm³
    Stability Stable under normal conditions

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    General Information
    Where to Buy Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate in China?
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    Frequently Asked Questions

    As a leading Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate
    Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate is widely used. In the field of medicine, it can be used as a key intermediate to synthesize compounds with specific biological activities. The construction of some drug molecules often depends on the active structure of this compound. Through specific chemical reactions, it is integrated into the drug skeleton to give the drug unique pharmacological properties, such as antibacterial, anti-inflammatory or anti-tumor effects.
    It is also useful in the field of materials science. Due to its structural properties, it can participate in the synthesis of certain polymer materials. After ingenious design and reaction regulation, it can be introduced into the main chain or side chain of the polymer to improve the properties of the material, such as enhancing the thermal stability and mechanical properties of the material, or endowing the material with special optical and electrical properties, so as to meet the diverse requirements of material properties in different application scenarios.
    In the field of organic synthetic chemistry, it is even more important as a synthetic building block. Chemists can use various organic reactions to functionally modify it according to its structural characteristics to construct more complex and diverse organic compounds, providing rich raw materials and possibilities for the development of organic synthetic chemistry and the creation of new compounds.
    What are the physical properties of Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate
    The methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylic acid ester is also an organic compound. Its physical properties are quite important and are detailed as follows:
    First appearance, this material is often white to light yellow crystalline powder, like fine sand, uniform texture, viewed under light, slightly glossy, like morning light sprinkling on fine sand.
    and melting point, about a certain temperature range, this temperature is just like the key node of its state transition, when heated to this point, the solid crystal gradually melts into a liquid state, just like ice and snow melting when warm. The characteristics of this melting point are crucial for the identification and purity judgment of substances.
    Furthermore, when it comes to solubility, it can be dissolved in organic solvents such as ethanol and acetone, just like fish get water, and the solute molecules are evenly dispersed among the solvent molecules to form a uniform and stable system. However, in water, its solubility is relatively limited, and it can only be dissolved a little, just like a stone thrown into a shallow stream, and it is difficult to form a miscible state. This difference in solubility has a profound impact on the separation, purification and choice of reaction environment of substances.
    has density, which is also one of its physical properties. The value of its density reflects the quality of the substance in a unit volume, which is like a scale for measuring the "compactness" of the substance. This characteristic is of great significance in many practical applications, such as the measurement and transportation of the substance.
    In addition, the stability of this substance cannot be ignored. Under normal conditions, it is relatively stable. When it encounters a hot topic, an open flame or a strong oxidant, the stability is easily damaged, or a chemical reaction is triggered, and there is even a potential safety risk. It is like throwing a boulder into a calm lake and causing waves. This stability consideration should be taken with caution during the storage and use of substances.
    What is the chemical synthesis method of Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate
    The chemical synthesis of methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylic acid esters is an important research in the field of organic synthesis. Its synthesis often follows the following steps:
    The choice of starting materials is mostly based on compounds with specific structures. If you choose pyrrole derivatives with suitable substituents, or related nitrogenous and oxygen-containing basic raw materials, this is the foundation for synthesis.
    The activation step is also critical. With specific reagents, the activity of specific parts of the starting material is increased, so that the subsequent reaction is smooth. If treated with acids, bases or special catalysts, the functional groups in the raw materials are activated.
    Cyclization reaction is the core. Under suitable reaction conditions, such as specific temperature, pressure and reaction time, the 2,5-dioxo structure of the pyrrole ring is constructed through intramolecular rearrangement, condensation and other reactions. This step requires precise regulation of the reaction conditions. Due to high or low temperature, too long or too short time, side reactions can be induced, affecting the yield and purity of the target product.
    Esterification is also indispensable. React with a suitable esterification reagent and a carboxyl-containing intermediate to introduce methyl groups to obtain methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate. In this process, the type and dosage of the reaction solvent and catalyst are also important, because they are all related to the reaction efficiency and product quality.
    The whole process of synthesis needs to be monitored by a variety of analytical methods, such as thin layer chromatography, nuclear magnetic resonance, mass spectrometry, etc., to determine the progress of each step of the reaction and the structure of the product, to ensure the accuracy of the synthesis path, and to achieve the purpose of efficient synthesis of the target product.
    What is the market price of Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate
    Methyl-2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate, this is an organic compound, which has important uses in many fields such as chemical industry and pharmaceutical research and development. However, its market price often fluctuates due to multiple factors, and it is difficult to determine the exact number.
    The first to bear the brunt is the cost of raw materials. The preparation of this compound requires specific raw materials. If raw materials are scarce, or its production is affected by natural conditions, policy regulation, etc., the price will rise, which will then affect the price of the finished product.
    Furthermore, the difficulty of the preparation process also affects. If the preparation process is complicated, high-end technology and precision equipment are required, and the reaction conditions are strict, the production cost will rise, and the market price will also increase accordingly.
    The relationship between supply and demand in the market is even more critical. If many industries have strong demand for this compound and limited supply, its price is bound to rise; conversely, if demand is flat and supply is sufficient, the price may stabilize or decline.
    In addition, the market competition situation should not be underestimated. If there are many manufacturers and the competition is fierce, the manufacturers may reduce prices to compete for market share; if the market is almost monopolized, the price may be controlled by a few companies.
    There are regional differences. Different regions, due to different levels of economic development, logistics costs, and tax policies, the selling price will also vary.
    Therefore, in order to know the exact market price of methyl-2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate, it is necessary to comprehensively consider the above factors and pay attention to market dynamics in real time in order to have a more accurate grasp.
    What are the safety precautions for Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate
    Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate, this is an organic compound. Regarding its safety precautions, it is necessary to check as follows:
    First, this substance is chemically active, and appropriate protective equipment must be worn during operation. Such as protective gloves, which can protect the skin of the hands from erosion; protective glasses, which can prevent this substance from splashing and injuring the eyes; wear laboratory clothes to prevent it from being contaminated with clothing and spreading to the body.
    Second, this compound may be toxic. If it comes into contact accidentally, rinse the contact area with plenty of water immediately. If it comes into contact with the eyes, you need to seek medical attention immediately after rinsing, and it must not be delayed. If you inhale it accidentally, you should quickly move it to a place with fresh air. If the symptoms of discomfort persist, you also need to seek medical attention. If you eat it by mistake, you should never induce vomiting. You should seek medical attention immediately and follow the doctor's advice.
    Third, when storing, keep it in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent fire or chemical reactions. At the same time, store it separately from oxidants, acids, bases, etc., to avoid interaction and dangerous accidents.
    Fourth, during use, the operating environment must be well ventilated, and volatile gaseous substances can be discharged in time by means of fume hoods and other equipment to reduce the concentration of this substance in the air and reduce its potential harm to the human body.
    In short, when handling methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate, it is necessary to strictly abide by safety procedures and be careful to ensure personal safety and the safety of the experimental environment.