Ethyl 6h Thieno 2 3 B Pyrrole 5 Carboxylate
pyridine pyrrole pyrazine piperidine piperazine

ETHYL 6H-THIENO[2,3-B]PYRROLE-5-CARBOXYLATE

    Specifications

    HS Code

    416861

    Chemical Formula C9H9NO2S
    Molar Mass 195.24 g/mol
    Appearance Solid (usually)
    Solubility In Water Low solubility (organic compound)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Stability Stable under normal conditions if stored properly

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of ETHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE
    ETHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE is an organic compound, and its Chinese name is 6H-thiopheno [2,3-b] pyrrole-5-carboxylic acid ethyl ester. Its chemical structure can be analyzed from each part.
    "ETHYL" Epiethyl, which is the remaining monovalent alkyl group after removing one hydrogen atom from ethane, has the structural formula of - C ² H.
    "6H-THIENO [2,3-B] PYRROLE" refers to 6H-thiopheno [2,3-b] pyrrole. Both thiophene and pyrrole are heterocyclic compounds. Thiophene is a sulfur-containing five-membered heterocyclic ring, and pyrrole is a nitrogen-containing five-membered heterocyclic ring. In this structure, the thiophene ring and the pyrrole ring are fused in a specific way, [2,3-b] indicates the fused position of the two, H in 6H represents the hydrogen atom, and 6 represents the position number of the hydrogen atom.
    "5-CARBOXYLATE" means 5-carboxylic acid ester, indicating that the carboxylic acid ester group is connected at the 5th position of the thiophene-pyrrole ring. Combined with "ETHYL", it can be seen that it is an ester formed by carboxylic acid and ethanol, that is, the compound containing - COOCH -2 CH ³ structure is connected to the 5th position of the thiophene-pyrrole ring.
    In summary, the chemical structure of ETHYL 6H - THIENO [2,3 - B] PYRROLE - 5 - CARBOXYLATE is an organic compound with thiopheno [2,3 - b] pyrrole as the parent ring and a carboxylic acid ethyl ester group at the 5th position.
    What are the main uses of ETHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE
    ETHYL 6H-THIENO [2,3 - B] PYRROLE - 5 - CARBOXYLATE is one of the organic compounds. This compound has a wide range of uses and has its own impact in various fields.
    First, in the field of medicinal chemistry, it is often a key intermediate for the creation of new drugs. Due to the unique molecular structure of this compound, it can be combined with specific biological targets in vivo or regulate physiological processes in vivo. Through chemical modification and derivatization, it is expected to develop potential drugs for treating many diseases such as cancer, cardiovascular diseases, and neurological diseases. For example, by fine-tuning its structure, researchers can enhance its targeting to specific cancer cells, thereby improving the efficacy of anti-cancer drugs and reducing the side effects on normal cells.
    Second, in the field of materials science, ETHYL 6H - THIENO [2,3 - B] PYRROLE - 5 - CARBOXYLATE also shows important value. Because of its special photoelectric properties, it can be applied to the preparation of organic optoelectronic devices. Such as Organic Light Emitting Diode (OLED), this compound can be used as a light-emitting layer material. With its unique luminous properties, it is expected to improve the luminous efficiency and color purity of OLEDs, so that it can be applied to the manufacture of high definition display screens, which contributes to the development of display technology. Or in the field of organic solar cells, it can serve as one of the active layer materials, participate in the generation and transmission of photogenerated charges, help improve the photoelectric conversion efficiency of solar cells, and promote progress in the field of renewable energy.
    Third, in organic synthetic chemistry, this compound is an important starting material for the construction of more complex organic molecules. Chemists can use its specific functional groups to gradually transform it into organic compounds with diverse structures through various organic reactions, such as nucleophilic substitution and cyclization reactions, to enrich the types of organic compounds, providing more material basis and possibilities for the research and development of organic chemistry.
    What is the synthesis method of ETHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE
    ETHYL 6H - THIENO [2,3 - B] PYRROLE - 5 - CARBOXYLATE is one of the organic compounds. The method of synthesis is as follows.
    Suitable compounds containing sulfur and nitrogen are often selected as starting materials. The sulfur heterocyclic and nitrogen heterocyclic precursors with specific structures can be taken first, and they can be cyclized with appropriate reagents and conditions. For example, the reaction of sulfur-containing alkenyl halides and nitrogen-containing amine compounds is heated in an organic solvent in the presence of a base. The alkali can be selected from potassium carbonate, sodium carbonate, and organic solvents such as N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), etc., which can provide a suitable environment for the reaction.
    During the reaction, the halogen atom of the alkenyl halide undergoes nucleophilic substitution with the nitrogen atom of the amine, and then intracellular cyclization is initiated, and the basic structure of thiopyrrole is preliminarily constructed.
    After that, for the obtained intermediate, a carboxyl ethyl ester group needs to be introduced. It can be reacted with halogenated ethyl acetate under the action of metal catalysts. Commonly used metal catalysts such as palladium catalysts, such as tetrakis (triphenylphosphine) The reaction is carried out in a suitable base and solvent system. The base can promote the activation of halogenated ethyl acetate, and the solvent ensures good dispersion and contact of the reaction substances.
    During the reaction process, close monitoring is required. The consumption of raw materials and the formation of products can be observed by thin layer chromatography (TLC). When the reaction reaches the desired level, the reaction mixture is treated by conventional separation and purification methods. First, the organic product is extracted from the reaction system by extraction with suitable organic solvents, such as ethyl acetate, dichloromethane, etc. After column chromatography, silica gel was selected as the stationary phase, and a suitable proportion of petroleum ether and ethyl acetate mixture was used as the mobile phase to separate the extract, remove impurities, and obtain pure ETHYL 6H - THIENO [2,3 - B] PYRROLE - 5 - CARBOXYLATE product. In this way, the target compound can be obtained.
    What are the physical properties of ETHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE
    ETHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE is an organic compound, and its physical properties are quite critical, which is related to the many uses and characteristics of this compound. The physical properties are described in detail below.
    First of all, the appearance of this compound is usually solid, its solid state or crystalline form, showing a regular geometric shape, and the texture may be more delicate, like the aggregation of tiny crystal particles.
    The melting point is one of the important physical properties. ETHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE a specific melting point. At this temperature, the compound will change from a solid state to a liquid state. The exact melting point needs to be determined experimentally, and the melting point of different purity samples may vary. Generally speaking, its melting point allows the compound to maintain a solid state stable structure at room temperature.
    The solubility cannot be ignored either. In organic solvents, ETHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE exhibit different solubility characteristics. In some organic solvents such as dichloromethane and chloroform, or with good solubility, it can be uniformly dispersed to form a solution. In water, due to its weak interaction with water molecules and poor solubility, it mostly exists in solid form in water and is difficult to dissolve with water. The density of
    is also an aspect of the physical properties of the compound. Its density determines the weight per unit volume, which is of great significance for the relationship between dosage and volume in practical applications. Although the specific density value needs to be accurately measured experimentally, the density characteristics affect the distribution and behavior of the compound in the mixed system.
    In addition, ETHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE volatile under certain conditions. However, due to its solid-state characteristics and molecular structural stability, the volatility is usually weak. At room temperature and pressure, the volatilization rate is slow, and it is not easy to quickly change from solid to gaseous state.
    ETHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE physical properties such as appearance, melting point, solubility, density and volatility have a profound impact on its application in organic synthesis, materials science and other fields. Studying and mastering these properties is the basis for the effective use of this compound.
    What is the market price of ETHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE
    ETHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE is an organic compound. As for its market price, it is difficult to tell. The price of this compound is affected by many factors.
    The first to bear the brunt is the difficulty of preparation. If its synthesis requires exquisite technology, rare raw materials, and complicated steps and low yield, the cost will be high and the price will be high. Such as ancient alchemy, wanting a rare pill, all kinds of materials are rare, the process is cumbersome, and the finished product price is high.
    Furthermore, the state of market supply and demand is also the key. If there is a strong demand for this product in the fields of medicine, materials, etc., but the supply is limited, just like the principle that the grain is cheap in a good year and the grain is expensive in a barren year, the price will rise. On the contrary, if there is little demand and sufficient supply, the price will tend to fall.
    The difference in origin also affects the price. Different places have different raw material costs, labor costs, and transportation conditions. For example, in a remote place, due to inconvenient transportation, the transportation cost of this compound may increase significantly, and the price of this compound produced in this place may be higher than that of a place with convenient transportation.
    The quality is also related to the price. Those with high purity and few impurities are like carefully selected beautiful jade, and the price is higher than those with poor quality.
    If you want to know the market price of ETHYL 6H-THIENO [2,3-B] PYRROLE-5-CARBOXYLATE, you should carefully consider the raw material market, production process, market demand and other factors, and it is advisable to consult chemical product suppliers, market survey agencies, or explore on relevant professional trading platforms to obtain a more accurate price.