Ethyl 3,5-dimethyl-2-formylpyrrole-4-carboxylate

Ethyl 3,5-dimethyl-2-formylpyrrole-4-carboxylate (ethyl 3,5-dimethyl-2-formylpyrrole-4-carboxylate), this is an organic compound with unique chemical properties.
It contains an ester group (-COOEt), so it has ester commonality. In case of acid or alkali, it can be hydrolyzed. In acidic medium, hydrolysis generates 3,5-dimethyl-2-formylpyrrole-4-carboxylic acid and ethanol; under basic conditions, the corresponding carboxylate and ethanol are generated. The hydrolysis reaction conditions are different and the rates are different.
The pyrrole ring in the molecule is rich in electrons, has aromatic properties, and can undergo electrophilic substitution reactions. Formalyl (-CHO) conjugates with pyrrole ring, resulting in changes in the distribution of electron clouds on the ring, and electrophilic substitution mostly occurs at higher electron cloud densities. For example, when halogenated, halogen atoms easily replace pyrrole ring activity check point hydrogen atoms.
In addition, formyl groups can undergo many reactions. It can be reduced to hydroxymethyl (-CH 2O OH), commonly used reducing agents such as sodium borohydride; it can also react with active hydrogen-containing compounds, such as alcohols, under acid catalysis to produce acetals. < Br >
Due to the existence of multiple active groups in the molecule, each group interacts with each other, making the compound widely used in the field of organic synthesis, it can be used as an intermediate to construct complex organic molecules through a series of reactions.

The method of synthesizing ethyl 3,5-dimethyl-2-formylpyrrole-4-carboxylic acid esters is often followed in several ways.
One method can be started from a suitable pyrrole derivative. First take the pyrrole with a specific substituent and apply it with an acylating agent. When acylating, the reaction conditions need to be carefully selected to ensure that the acyl group is precisely introduced into the 2-position of the pyrrole ring to form a 2-formylpyrrole intermediate. Here, the properties of the acylating agent, the temperature of the reaction, and the choice of the solvent are all important factors. The temperature is related to the speed and selectivity of the reaction; the quality of the solvent affects the solubility of the reagent and the intermediary of the reaction.
Then, to obtain 2-formyl pyrrole intermediates, carboxylic acid ester groups are introduced. Often reagents containing ester groups react with intermediates under alkali or specific catalytic conditions. The strength and amount of base, and the catalytic effect all affect the reaction path and yield.
Another method may start with the strategy of constructing pyrrole rings. Using small molecules containing appropriate substituents as binders, through a series of reactions such as condensation and cyclization, the pyrrole ring structure is constructed, and methyl, formyl and carboxylic acid ester groups are implanted at the same time. The control of the order and conditions of the condensation and cyclization reactions is extremely critical. The temperature and time of condensation, and the triggering conditions of cyclization can all determine the purity and amount of the product.
And after the reaction is completed, it often needs to be separated and purified. Or by chromatography, according to the difference in the polarity of the compound, the product and impurities are separated; or by recrystallization, according to the difference in solubility, to obtain pure ethyl 3,5-dimethyl-2-formylpyrrole-4-carboxylic acid ester. All methods have their own advantages and disadvantages. When implementing, it is good to choose according to the availability of raw materials, cost considerations, yield and purity.

Ethyl 3,5-dimethyl-2-formylpyrrole-4-carboxylate (3,5-dimethyl-2-formylpyrrole-4-carboxylate) is widely used in the field of organic synthesis.
First, it is often a key intermediate for the construction of complex pyrrole compounds. Pyrrole structures are common in many natural products and bioactive molecules. Using this compound as a starting material, through various chemical reactions, such as nucleophilic addition and condensation, the substituents of pyrrole rings can be ingeniously modified, and then derivatives with diverse biological activities can be created. For example, in the field of medicinal chemistry, researchers can modify their structures in order to obtain novel compounds with potential pharmacological activities for the treatment and research of diseases.
Second, it also has its uses in materials science. Because it contains specific conjugated structures and functional groups, materials with unique optical and electrical properties can be prepared through rational design and transformation. For example, by polymerizing with other functional monomers, new functional materials for organic Light Emitting Diodes (OLEDs), solar cells and other optoelectronic devices are expected to be obtained, and their structural properties can be used to achieve efficient photoelectric conversion or luminescence.
Third, it also plays an important role in the total synthesis of natural products. Many natural products contain pyrrole skeletons. Ethyl 3,5-dimethyl-2-formylpyrrole-4-carboxylate can be used as a starting module to gradually construct the complete structure of natural products through multi-step reactions, which helps to further explore the chemical properties and biological activities of natural products.

Ethyl 3,5 - dimethyl - 2 - formylpyrrole - 4 - carboxylate is an organic compound. When storing, many matters need to be paid attention to.
Temperature and humidity of the first environment. This compound is quite sensitive to temperature and humidity, and high temperature can easily cause its chemical properties to change, or cause decomposition reactions; if the humidity is too high, it may cause it to be damp, affecting purity and stability. Therefore, it should be stored in a cool and dry place. The temperature should be controlled between 15 ° C and 25 ° C, and the relative humidity should be maintained at 40% to 60%.
Times and light effects. Light, especially direct light, may cause photochemical reactions, resulting in structural changes and reduced activity. Therefore, the storage place must be shaded, and it can be placed in a brown bottle or a container wrapped with shading material.
Furthermore, this compound has a certain chemical activity and can come into contact with other substances or react chemically. When storing, avoid coexisting with strong active substances such as oxidants, acids, and bases to prevent accidental reactions. Storage containers should also be carefully selected. Glass materials are stable and can be used as the first choice, but it is necessary to pay attention to whether there is any potential reaction with the contents; if using plastic containers, it should be ensured that the material does not interact with the compound.
In addition, the ventilation condition of the storage area cannot be ignored. Good ventilation can disperse volatile gases that may leak in time and reduce safety risks. And the storage place should be clearly marked, indicating the name of the compound, properties, storage conditions and other key information, which is convenient for access and management, and can also provide important reference for handlers in emergency situations. In this way, it can ensure that Ethyl 3,5-dimethyl-2-formylpyrrole-4-carboxylate remains stable during storage and reduces the risk of deterioration.

Ethyl 3,5 - dimethyl - 2 - formylpyrrole - 4 - carboxylate is an organic compound whose market price range is difficult to determine. The price is often influenced by many factors, such as the cost of raw materials, the process of preparation, the supply and demand of the market, and the scale of production.
If the raw materials are easy to purchase and low cost, the preparation process is simple and efficient, the production scale is quite large, and the market supply is abundant, the price may be relatively low. On the contrary, the raw materials are rare and difficult to find, the preparation process is complicated, requires a lot of resources and energy, and the market demand is strong, the supply is scarce, and the price will rise.
According to past market transactions and price movements of similar compounds, in regular commercial transactions, the price per gram may fluctuate between tens of yuan and hundreds of yuan. However, this is only a rough estimate, not an accurate pricing. In the actual market, its price may vary significantly from time to place.
If you want to get an accurate price, you should consult a supplier specializing in organic chemical reagents, or consult the recent market quotation information. Suppliers can provide the most accurate price information based on current inventory, procurement costs and market conditions.