Ethyl 3 5 Dimethyl 1h Pyrrole 2 Carboxylate
pyridine pyrrole pyrazine piperidine piperazine

Ethyl 3,5-Dimethyl-1H-Pyrrole-2-Carboxylate

    Specifications

    HS Code

    575831

    Chemical Formula C10H13NO2
    Molecular Weight 179.22 g/mol
    Appearance Solid
    Color Off - white to light yellow
    Melting Point 74 - 76 °C
    Boiling Point 269.5 °C at 760 mmHg
    Density 1.075 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Flash Point 116.8 °C
    Stability Stable under normal conditions

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    General Information
    Where to Buy Ethyl 3,5-Dimethyl-1H-Pyrrole-2-Carboxylate in China?
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    Frequently Asked Questions

    As a leading Ethyl 3,5-Dimethyl-1H-Pyrrole-2-Carboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of Ethyl 3, 5-Dimethyl-1H-Pyrrole-2-Carboxylate?
    Ethyl 3,5 - Dimethyl - 1H - Pyrrole - 2 - Carboxylate (3,5 - dimethyl - 1H - pyrrole - 2 - carboxylate ethyl ester) has a wide range of uses. In the field of organic synthesis, it is a key intermediate. Due to its unique molecular structure and active reaction check point, it can construct complex organic structures through various chemical reactions.
    First, in pharmaceutical chemistry, this is used as a starting material to modify the substituents on the pyrrole ring to create many bioactive compounds. Or it can adjust its interaction with biological targets, and then develop new therapeutic drugs, such as antibacterial, anti-inflammatory, and anti-tumor genera.
    Second, in the field of materials science, it can participate in the preparation of functional polymer materials. After polymerization, this structure is introduced into the main chain or side chain of the polymer to impart specific optical and electrical properties to the material, such as the preparation of polymers with fluorescent properties for photoelectric display, sensors, etc.
    Furthermore, in the synthesis of fine chemicals, it is also an important component. It can be used to synthesize fragrances, dyes, etc. Based on it, through functional group transformation, various fine chemicals with unique flavors or colors can be derived to meet the needs of daily chemical, printing and dyeing industries.
    In summary, Ethyl 3,5 - Dimethyl - 1H - Pyrrole - 2 - Carboxylate has important uses in many fields such as organic synthesis, drugs, materials and fine chemicals due to its own structural characteristics, promoting the development and innovation of various fields.
    What are the synthesis methods of Ethyl 3, 5-Dimethyl-1H-Pyrrole-2-Carboxylate
    There are many ways to synthesize ethyl 3,5-dimethyl-1H-pyrrole-2-carboxylic acid esters. In the past, many wise people have explored many things, and there are many methods for forming them.
    First, it can be started by a suitable starting material through a condensation reaction. For example, a specific nitrogen-containing compound and a carboxyl group derivative can be used in a suitable reaction medium, supplemented by a specific catalyst, to control the temperature and pressure to make it condensate. This process requires a delicate grasp of the reaction conditions. If the temperature is too high, it is easy to cause a cluster of side reactions, and if it is too low, the reaction will be slow and difficult to achieve expectations.
    Furthermore, it can be obtained by cyclization reaction. Select a suitable chain-like precursor, which contains cyclized active groups in its structure. In an appropriate reaction system, by adjusting the reaction parameters, the intramolecular cyclization is promoted, and the target pyrrole ring structure is formed. Then esterification is carried out, and ethyl carboxylic acid ester groups are introduced to obtain ethyl 3,5-dimethyl-1H-pyrrole-2-carboxylic acid esters.
    There is also a method of conversion by functional groups. Compounds containing similar structures are prepared first, and then modified and transformed by a series of functional groups, and the desired methyl, carboxylethyl ester and other groups are gradually introduced. This approach requires familiarity with the mechanisms and conditions of various functional group conversion, and careful selection of reagents and reaction steps in order to achieve the purpose of synthesis smoothly.
    The various methods for synthesizing this compound have their own advantages and disadvantages. It is necessary to choose the good one according to the actual situation, such as the availability of raw materials, cost considerations, and the difficulty of reaction operation, in order to efficiently synthesize ethyl 3,5-dimethyl-1H-pyrrole-2-carboxylate.
    What are the physical properties of Ethyl 3, 5-Dimethyl-1H-Pyrrole-2-Carboxylate?
    Ethyl 3,5 - Dimethyl - 1H - Pyrrole - 2 - Carboxylate, that is, ethyl 3,5 - dimethyl - 1H - pyrrole - 2 - carboxylate, is one of the organic compounds. Its physical properties are as follows:
    Looking at its morphology, it is mostly a colorless to light yellow liquid under normal circumstances, with a clear texture. This state is convenient for it to blend with other substances in many chemical reaction systems to promote the reaction process smoothly.
    Smell its odor, emitting a weak and specific aroma, which may be derived from the synergistic effect of pyrrole ring and ester group structure. Although its taste is not strong, it is still necessary to pay attention to ventilation during operation and use to prevent irritation to the olfactory system.
    When it comes to boiling point, it is about a certain temperature range. Specifically, because the exact boiling point is affected by factors such as external pressure, it usually has a boiling point of about [X] ° C under normal pressure. A higher boiling point indicates that the intermolecular force is relatively strong. During the process of heating separation or purification, it is necessary to control the appropriate temperature to achieve effective separation.
    As for the melting point, it is also in a specific range, about [X] ° C. The melting point characteristics are quite significant for identifying the purity of the compound. If the purity is not good, the melting point may decrease and the melting range may widen. < Br >
    In terms of solubility, this compound is difficult to dissolve in water, because water is a polar solvent, and the molecular polarity of this substance is relatively weak. However, it exhibits good solubility in common organic solvents such as ethanol, ether, dichloromethane, etc. This solubility characteristic makes it widely used in organic synthesis, extraction and separation, etc. It can choose a suitable organic solvent for dissolution operation according to different needs, and help the reaction to carry out or the separation of substances.
    In terms of density, compared with common organic solvents, it has a certain value, about [X] g/cm ³. This density characteristic is crucial in operations involving stratification, phase separation, etc., so that its distribution in the mixed system can be anticipated, providing an important basis for experimental operations.
    What are the chemical properties of Ethyl 3, 5-Dimethyl-1H-Pyrrole-2-Carboxylate
    Ethyl 3,5-dimethyl-1H-pyrrole-2-carboxylate is an organic compound with interesting chemical properties and a wide range of uses in the field of organic synthesis.
    From its structural perspective, the molecule contains a pyrrole ring, which is a five-membered nitrogen-containing heterocycle, giving the compound unique electronic properties. The methyl groups at positions 3 and 5 on the pyrrole ring can affect the electron cloud distribution of the molecule due to their electron-giving effect, which in turn affects its reactivity. The ethyl carboxylate group at position 2 not only adds polarity to the molecule, but also introduces many reactive check points.
    In terms of chemical properties, the nitrogen atom of the pyrrole ring in this compound has a certain alkalinity. Although the alkalinity of the conjugation effect is weak, it can still react with the acid under certain conditions to generate the corresponding salt. At the same time, the pyrrole ring is prone to attack by electrophilic reagents due to electron-rich, and electrophilic substitution reactions occur. The substitution check point is often affected by the localization effect of substituents such as methyl.
    Furthermore, the chemical properties of the ethyl carboxylate group cannot be underestimated. This group can undergo hydrolysis reaction. Under acidic or basic conditions, ester bonds are broken to form 3,5-dimethyl-1H-pyrrole-2-carboxylic acid and ethanol, respectively. Under basic conditions, hydrolysis is more thorough, and this hydrolysis reaction is often used in organic synthesis to prepare corresponding carboxylic acids.
    In addition, the compound can also participate in reverse reactions such as esterification reactions. Under appropriate catalysts and conditions, it undergoes ester exchange reactions with alcohols to generate different ester compounds. This reaction provides a diverse way for organic synthesis.
    At the same time, due to the existence of unsaturated bonds in the molecule, under appropriate conditions, addition reactions may also occur, thereby enriching the structure of the molecule and expanding its application in the fields of organic synthesis and materials science.
    What is the price range of Ethyl 5-Dimethyl-1H-Pyrrole-2-Carboxylate in the market?
    I don't know the price range of "Ethyl 3,5 - Dimethyl - 1H - Pyrrole - 2 - Carboxylate" in the market. However, if you want to know its price, you can explore it in various ways.
    First, visit the chemical reagent supplier. There are many chemical reagent companies in the city, which often supply various chemical substances. You can send it to inquire there, or check the price of this compound on its official website. Different suppliers may have different prices due to different sources, costs, and business strategies.
    Second, look at the online chemical trading platform. In today's world, online trading is prosperous, and many chemical trading platforms list various products. Log in to such platforms to search for this compound, and you can check the quotations of different merchants to clarify its approximate price range.
    Third, consult people in the chemical industry. Those who are employed in the chemical industry, or are familiar with market conditions, know the price changes of this compound. Communicating with them may provide valuable information.
    However, market prices change rapidly and are influenced by factors such as raw material costs, supply and demand, and production processes. Therefore, in order to obtain accurate prices, it is necessary to inquire in real time and compare with multiple parties to obtain them.