Ethyl 2-methyl-4H-furo[3,2-b]pyrrole-5-carboxylate

The Chinese name corresponding to "Ethyl 2-methyl-4H-furo [3,2-b] pyrrole-5-carboxylate" is ethyl 2-methyl-4H-furano [3,2-b] pyrrole-5-carboxylate. Its chemical structure can be expressed as follows:
This compound contains a special heterocyclic structure formed by fusing furan and pyrrole. The furan ring and pyrrole ring are connected by specific atoms to form a fused ring system, that is, the furano [3,2-b] pyrrole structure. In this fused ring system, a methyl group is connected at position 2, and a carboxylate group is connected at position 5.
Structurally, the furan ring is a five-membered unsaturated heterocyclic ring composed of four carbon atoms and one oxygen atom, which is aromatic. The pyrrole ring is also a five-membered unsaturated heterocyclic ring composed of four carbon atoms and one nitrogen atom, which also has aromatic properties. After fusing the two, a unique electron cloud distribution and chemical activity are formed.
Carboxylate ethyl ester group (-COOCH -2 CH
) is connected to the fifth position of the furano [3,2 - b] pyrrole fused ring system through carbon atoms. This group endows the compound with certain ester chemical properties, such as hydrolysis and alcoholysis. The methyl group attached to the No. 2 position will affect the electron cloud density distribution and spatial structure of the whole molecule, thereby affecting its physicochemical properties and chemical reactivity. This structural feature makes 2-methyl-4H-furano [3,2-b] pyrrole-5-carboxylate ethyl ester may show unique properties and application potential in organic synthesis, medicinal chemistry and other fields.

Ethyl 2-methyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid ester is an organic compound. Its physical properties are unique, let me tell them one by one.
Looking at its appearance, under normal temperature and pressure, it is mostly in the state of a crystalline solid. Due to the strong interaction force between molecules, the molecules are arranged in an orderly manner, and then a crystalline structure is formed.
Regarding the melting point, after many experiments, the melting point is about a certain temperature range, which is of great significance for its physical morphological transformation. When the temperature rises to the melting point, the molecule obtains enough energy to overcome the lattice energy and convert from a solid state to a liquid state.
In terms of solubility, this compound exhibits good solubility in organic solvents such as dichloromethane and chloroform. Due to the fact that the molecules of organic solvents can form similar forces with the molecules of this compound, such as van der Waals force, hydrogen bond, etc., following the principle of "similar miscibility". However, in water, its solubility is poor, because its molecular structure has a large proportion of hydrophobic groups, and the force between water molecules is weak, making it difficult to mix with water.
In addition, the density of this compound is also one of its important physical properties. Under certain conditions, its density can be accurately measured to obtain specific values. This value reflects the mass of the substance per unit volume, which is very beneficial for its application and properties in different environments.
Furthermore, the boiling point of ethyl 2-methyl-4H-furo [3,2-b] pyrrole-5-carboxylate also has a specific value at atmospheric pressure. The boiling point is the temperature at which a liquid turns into a gas, and this temperature reflects the strength of the intermolecular forces. When the temperature reaches the boiling point, the molecule has enough energy to break free from the liquid phase and escape into the gas phase.
The above physical properties play a crucial role in many fields such as organic synthesis and drug development. Researchers can choose the separation, purification and reaction conditions reasonably according to their physical properties for research purposes.

Ethyl 2 - methyl - 4H - furo [3,2 - b] pyrrole - 5 - carboxylate is also an organic compound. There are many synthesis methods, common methods, which can be obtained from raw materials containing furan and pyrrole structures through multi-step reactions.
First, you can start from furan derivatives with appropriate substituents. First modify the furan ring and introduce suitable active groups, such as halogen atoms or carbonyl groups. In this process, the reaction conditions, such as temperature, solvent and catalyst, need to be carefully selected to ensure the selectivity and yield of the reaction. For example, with a specific halogenating agent, in the presence of a suitable base, in an inert solvent, a specific position of the furan ring can be halogenated.
In the second case, the modified furan derivative is condensed with pyrrole compounds. This reaction may require the help of specific condensing agents, such as some dehydrating agents or nucleophiles. By adjusting the reaction conditions, the furan is connected to the pyrrole structure to construct the basic skeleton of the target compound.
In addition, for the obtained preliminary product, further functional group conversion may be required. If you want to introduce an ethyl ester group, an esterification reaction can be used. The corresponding carboxylic acid and ethanol are heated under the action of acidic catalysts such as concentrated sulfuric acid or p-toluenesulfonic acid to achieve the introduction of ethyl ester groups. At the same time, for the introduction of methyl groups, methylation reagents such as iodomethane or dimethyl sulfate can be used to methylate suitable activity check points under basic conditions.
The whole process of synthesis requires fine control of the conditions of each step of the reaction, strict monitoring of the reaction process, and analysis methods such as thin layer chromatography and nuclear magnetic resonance to confirm the structure and purity of the product, so that Ethyl 2-methyl-4H-furo [3,2-b] pyrrole-5-carboxylate can be synthesized efficiently and accurately.

Ethyl 2 - methyl - 4H - furo [3,2 - b] pyrrole - 5 - carboxylate is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry. It can be cleverly converted into compounds with unique biological activities through specific chemical reactions, which can be used to develop new drugs or to explore potential treatment options for certain diseases.
In the field of materials science, it can participate in the synthesis of polymer materials with special properties. Through rational design and reaction, the resulting materials can exhibit excellent properties in optics, electricity, etc., such as the preparation of materials with unique luminescence properties, which can be used in the field of optical display, contributing to the development of display technology.
In organic synthetic chemistry, it is an important cornerstone for building complex organic molecular structures. With its special molecular structure and reactivity, chemists can use this as a starting material to construct a variety of organic compounds with novel structures and unique functions through a series of delicate reaction steps, promoting the continuous progress and development of organic synthetic chemistry, and providing a richer and more diverse material basis for many fields.

Ethyl 2 - methyl - 4H - furo [3,2 - b] pyrrole - 5 - carboxylate is an organic compound, and the following kinds of derivatives are common.
One is a derivative obtained by introducing different groups on the pyrrole ring or furan ring through substitution reaction. For example, the introduction of alkyl groups on the pyrrole nitrogen atom can be achieved by suitable alkylation reagents under suitable reaction conditions. In this way, the physical and chemical properties of the formed derivatives will be changed due to the electronic and spatial effects of alkyl groups on the nitrogen atom.
Second, the carboxyl group is derived. The carboxyl group can be converted into an amide group, which can be obtained by reacting with an amine compound under the action of a condensing agent. The resulting amide derivatives either exhibit specificity in biological activity or differ from the original compound in crystal structure.
Third, the methyl group is modified. For example, the methyl group can be converted into a carboxyl group by oxidation reaction, so that a derivative with two carboxyl groups can be obtained. Such derivatives may exhibit unique properties in participating in polymerization reactions or coordinating with metal ions.
Or by halogenation, halogen atoms are introduced at suitable positions in the furan ring or pyrrole ring. The introduction of halogen atoms not only changes the polarity of the molecule, but also acts as a good leaving group in the subsequent nucleophilic substitution reaction, laying the foundation for the further construction of more complex derivatives.
Furthermore, through cyclization, the compound is intermolecular or intramolecular cyclized with other molecules with appropriate functional groups to form more complex structures such as fused rings or bridge rings, which can also give rise to many new compounds, and these new derivatives may emerge in the fields of medicinal chemistry, materials science and other fields.