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What is the chemical structure of Diethyl 3-amino-1H-2, 4-pyrroledicarboxylate?
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This compound is called diethyl 3-amino-1H-2,4-pyrroledicarboxylate. Its core structure is a pyrrole ring, which is a five-membered nitrogen-containing heterocyclic ring. At the first position of the pyrrole ring, there is no substituent, and it is connected by a hydrogen atom, so it has the label "1H". At the second and fourth positions of the pyrrole ring, there is a carboxylethyl ester structure. This carboxyl ethyl ester is formed by the esterification reaction of carboxyl group and ethanol, that is, the structure of -COOCH -2 CH
From this point of view, the structure of this compound is connected by the pyrrole ring as the base, supplemented by carboxyl ethyl ester and amino group, to form a unique chemical structure. The atoms and groups in the structure are covalently linked to each other to form a stable chemical entity, which is the chemical structure of "Diethyl 3-amino-1H-2,4-pyrroledicarboxylate".
What are the main uses of Diethyl 3-amino-1H-2, 4-pyrroledicarboxylate?
Diethyl 3-amino-1H-2,4-pyrrole dicarboxylate is an important intermediate in organic synthesis and has key uses in many fields.
First, in the field of medicinal chemistry, it is often used as a key building block for drug synthesis. The geny pyrrole ring structure is widely found in many bioactive molecules. The specific functional group of diethyl 3-amino-1H-2,4-pyrrole dicarboxylate can be skillfully introduced into the molecular structure of the target drug through various reactions, such as substitution reactions and condensation reactions, by means of organic synthesis, giving the drug unique biological activities, such as antibacterial, anti-inflammatory, and anti-tumor effects. For example, by modifying the substituents on the pyrrole ring, the interaction between the drug and the biological target can be adjusted to optimize the efficacy and selectivity of the drug.
Second, in the field of materials science, it also has applications. It can participate in the preparation of functional polymer materials, such as optoelectronic materials. Due to its specific electronic properties, the molecular structure can be polymerized or copolymerized with other functional monomers to construct materials with unique optical and electrical properties. Such materials may be applied to organic Light Emitting Diodes (OLEDs), solar cells and other fields to improve the photoelectric conversion efficiency and stability of materials.
Thirdly, in the field of total synthesis of natural products, diethyl 3-amino-1H-2,4-pyrrolide dicarboxylate also plays an important role. The core structure of many natural products contains pyrrole ring fragments. With this compound as the starting material, a series of complex organic synthesis strategies can be used to achieve total synthesis of natural products. By simulating the biosynthetic pathway of natural products, the clever use of this intermediate will help to further explore the biological activity and mechanism of action of natural products, laying the foundation for the development of new drugs and the rational utilization of natural product resources.
In summary, diethyl 3-amino-1H-2,4-pyrrolide, with its unique molecular structure, plays an indispensable role in many key fields such as drug research and development, material preparation, and total synthesis of natural products, and promotes the continuous progress and development of related science and technology.
What are the synthesis methods of Diethyl 3-amino-1H-2, 4-pyrroledicarboxylate?
There are several ways to prepare diethyl 3-amino-1H-2,4-pyrrole dicarboxylate. First, it can be prepared from suitable starting materials through a multi-step reaction. First, take the compound containing the pyrrole ring, and introduce the amino group with a suitable amination reagent under specific reaction conditions. Among them, the reaction temperature, time, and reagent ratio need to be carefully adjusted to enable the amino group to accurately access the target position.
Then, the carboxyl group on the pyrrole ring is treated with an esterification reagent to esterify the carboxyl group on the pyrrole ring with ethanol to form the desired bis-ethyl ester structure. During the reaction, attention should be paid to the selection and dosage of catalysts to promote the efficient progress of the reaction and avoid unnecessary side reactions. < Br >
Second, other related compounds can also be used as the starting point, and the gradual functional group transformation is achieved. First construct the basic skeleton of the pyrrole ring, and reserve the functional groups that can be converted into carboxyl and amino groups. Through clever reaction sequence, carboxyl-related esterification is carried out first, and then amino groups are introduced at appropriate stages. In this path, the purification and identification of the intermediates in each step of the reaction is crucial to ensure the purity and structural correctness of the final product.
Third, you can learn from the mature methods reported in the literature and make slight adjustments according to your own experimental conditions. Refer to the previous experience in the synthesis of similar compounds, optimize the reaction parameters, such as selecting more efficient catalysts, improving the reaction solvent system, etc., to make the synthesis process more convenient and efficient, and the product yield and purity are good. However, no matter what method, every step of the reaction needs to be carefully controlled, and modern analytical methods, such as nuclear magnetic resonance, mass spectrometry, etc., can accurately identify the structure and purity of the product to achieve the desired synthesis goal.
What are the physical properties of Diethyl 3-amino-1H-2, 4-pyrroledicarboxylate?
Diethyl 3-amino-1H-2,4-pyrrolidinate, this is an organic compound. Its physical properties are quite elegant, as follows:
Looking at its appearance, it is often in the state of white to light yellow crystalline powder, which is easy to identify and distinguish. Its pure color and regular crystalline structure lay the initial foundation for its many subsequent applications.
When it comes to the melting point, it is in a specific temperature range. This property is crucial for identification and purity judgment. When heated to this temperature range, the compound gradually changes from a solid state to a liquid state. This process is accurate and stable, reflecting the characteristics of the forces between its molecular structures.
The boiling point also has a certain value. Under specific pressure conditions, the temperature at which a compound converts from liquid to gaseous state is the boiling point. The determination of the boiling point helps to understand the physical state changes of the substance under different temperature environments, which is of great significance for its separation and purification processes.
In terms of solubility, it shows certain solubility in some organic solvents. Organic solvents such as ethanol and acetone can interact with it to disperse the compound into a homogeneous system. However, the solubility in water is relatively limited, and this difference is due to the degree of matching between the polarity of the compound molecule and the polarity of the water molecule.
Density is also one of the important physical properties. At a specific temperature, the mass of a unit volume is constant. This value not only reflects the characteristics of the substance itself, but also provides a basis for precise control of the dosage when mixing, proportioning, etc.
In addition, the stability of the compound is acceptable. Under general environmental conditions, it can maintain its own structure and properties relatively stable. However, in case of extreme conditions such as high temperature, strong acid, and strong base, the molecular structure may change, causing changes in properties.
In summary, the physical properties of diethyl 3-amino-1H-2,4-pyrrole dicarboxylate cover various aspects such as appearance, melting point, boiling point, solubility, density and stability. Each property is interrelated and together determines its application and treatment in different fields.
What is the market prospect of Diethyl 3-amino-1H-2, 4-pyrroledicarboxylate?
Today, there are things called Diethyl 3 - amino - 1H - 2,4 - pyrroledicarboxylate. This is an organic compound that has attracted much attention in the chemical and pharmaceutical fields. Looking at its market prospects, it seems to have considerable potential.
In the field of chemical industry, this compound is often used as an intermediate. With the continuous expansion of the chemical industry, the demand for fine chemicals is increasing. Many new materials are developed, and this intermediate is often relied on to produce specific structural compounds. Therefore, in the chemical market, the demand may be increasing. If high-end polymer materials are prepared, such intermediates containing special functional groups are required to give the materials unique properties, such as high strength and chemical resistance.
As for the field of medicine, its potential cannot be underestimated. Many studies have shown that the compound structure may have biological activity and can participate in drug synthesis. At present, the pharmaceutical industry has an urgent need for innovative drugs and is committed to the development of new target drugs. This compound may have its place in the research and development of anti-tumor and antiviral drugs. Taking anti-tumor drugs as an example, by rationally modifying their structures, drugs that can target specific tumor cells may be designed to add new avenues to cancer treatment.
However, its market development also faces challenges. The synthesis process is complex, resulting in high production costs and limiting large-scale application. And the market competition is fierce, with many companies and scientific research institutions competing for related technologies and products. If we want to expand the market, we should strive to optimize the synthesis process, reduce costs and enhance product competitiveness.
Overall, Diethyl 3 - amino - 1H - 2,4 - pyrroledicarboxylate market prospects are bright, but it is necessary to overcome many difficulties in order to gain a firm foothold in the market and maximize its value.