Diethyl 3 5 Dimethyl 1h Pyrrole 2 4 Dicarboxylate
pyridine pyrrole pyrazine piperidine piperazine

Diethyl-3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate

    Specifications

    HS Code

    589652

    Chemical Formula C14H19NO4
    Molecular Weight 265.305 g/mol
    Appearance Typically a solid (appearance may vary based on purity and preparation)
    Physical State At Room Temperature Solid
    Melting Point Data may vary depending on purity, generally needs experimental determination
    Boiling Point Data may vary depending on purity, generally needs experimental determination
    Solubility In Water Low solubility, as it is an organic compound with non - polar groups
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, ethyl acetate
    Density Data may vary depending on purity, generally needs experimental determination
    Flash Point Data may vary depending on purity, generally needs experimental determination
    Pka No significant acidic or basic functional groups for common pKa values in aqueous solution
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

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    Frequently Asked Questions

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    What are the chemical properties of Diethyl-3,5-dimethyl-1H-pyrrole-2, 4-dicarboxylate?
    Diethyl-3,5-dimethyl-1H-pyrrole-2,4-dicarboxylic acid ester, this is an organic compound. It has specific chemical properties, which are described in detail by you below.
    Looking at its structure, the pyrrole ring is the core, and there are methyl groups at the 3rd and 5th positions on the ring, and ethyl dicarboxylate at the 2nd and 4th positions. This structure gives it unique chemical activity.
    Let's talk about the physical properties first. At room temperature, it may be a solid or a liquid, depending on the intermolecular forces and structural characteristics. Its melting point and boiling point are affected by molecular mass and intermolecular forces. The relative density is also related to the structure, or similar to that of common organic solvents.
    Besides chemical properties, ester groups have typical properties. Hydrolysis can occur. Under the catalysis of acid or base, the alkoxy group in the ester group interacts with water to break the ester bond. Under acidic conditions, it slowly hydrolyzes to diethyl-3,5-dimethyl-1H-pyrrole-2,4-dicarboxylic acid and ethanol; under basic conditions, hydrolysis is accelerated to form carboxylic salts and ethanol. This hydrolysis reaction is a method for preparing corresponding carboxylic acids in organic synthesis.
    Alcoholysis can also occur. Under the action of catalysts with different alcohols, the alkoxy group in the ester group is replaced by the alkoxy group of the new alcohol to form a new ester. This reaction can be used to synthesize special structure ester compounds.
    The pyrrole ring is also active. There are unshared electron pairs on the nitrogen atom, which increases the electron cloud density of the pyrrole ring and has a certain nucleophilicity. It can undergo electrophilic substitution reaction with electrophilic reagents. Because the methyl group is the power supply group, it will affect the selectivity of the reaction check point. Substitution reactions may occur more easily in positions with higher electron cloud density.
    In addition, the compound may have certain stability. However, in case of extreme conditions such as strong oxidants and high temperatures, the structure may be damaged. Because of its carbon-carbon double bonds, ester groups and other functional groups, different functional groups interact with each other, which makes the chemical properties rich and may have potential uses in organic synthesis, medicinal chemistry and other fields.
    What are the preparation methods of Diethyl-3, 5-dimethyl-1H-pyrrole-2, 4-dicarboxylate?
    There are several common methods for preparing diethyl-3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate.
    First, it can be obtained from a suitable starting material through a multi-step reaction. First, take a compound with a suitable substituent, such as methyl-containing ketones and alarms, and carry out a condensation reaction under specific conditions. This condensation reaction requires a suitable catalyst to control the reaction temperature and time, so that the two condensate to form a key intermediate. Subsequently, the intermediate undergoes a cyclization reaction to construct a pyrrole ring structure. This cyclization process also requires precise regulation of reaction conditions, such as the selection of suitable bases or acids to promote intramolecular cyclization and generate preliminary pyrrole derivatives. Finally, the derivative is esterified to convert its carboxyl group into ethyl ester group, so as to obtain the target product diethyl-3,5-dimethyl-1H-pyrrole-2,4-dicarboxylic acid ester.
    Second, a specific pyrrole derivative is also used as the starting material and its substituent is modified. For example, first obtain a pyrrole compound containing a modifiable substituent, and then use an esterification reagent to convert the group at a specific position on the pyrrole ring into an ethyl ester group under mild reaction conditions, while retaining or modifying the methyl group at other positions. After a series of reaction operations, the desired product can also be successfully prepared. The entire preparation process requires attention to the sequence of reaction steps, and strict control of the reaction conditions of each step, including reaction temperature, reactant ratio, catalyst type and dosage, etc., to improve the purity and yield of the product.
    What is the main use of Diethyl-3, 5-dimethyl-1H-pyrrole-2, 4-dicarboxylate?
    Fudiethyl-3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate has a wide range of uses in the field of organic synthesis. First, it can be a key intermediate for drug synthesis. It has a unique structure, contains a pyrrole ring, and has a specific chemical activity and spatial configuration. Based on this, chemists can introduce various functional groups into its structure to construct compounds with specific pharmacological activities according to the needs of drug design. If you want to make antimalarial drugs, you can synthesize new drugs with Plasmodium inhibitory activity by modifying diethyl-3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate. < Br >
    Second, it can also be used in materials science. Due to its chemical stability and certain conjugate structure, it may be used to prepare organic optoelectronic materials. With appropriate chemical modification and processing, it may become an active material component of organic Light Emitting Diode (OLED), organic solar cells and other devices, improve the photoelectric properties of materials, and open up new avenues for the research and development of new optoelectronic devices.
    Furthermore, in the field of synthesis of heterocyclic compounds, it is also an important starting material. Pyrrole ring is the key structural unit of heterocyclic chemistry. Using dicarboxylic acid esters as starting materials, more complex heterocyclic systems can be constructed through various organic reactions, such as cyclization and condensation, etc., enriching the types and structures of heterocyclic compounds, and contributing to the development of organic synthetic chemistry.
    What is the market price of Diethyl-3,5-dimethyl-1H-pyrrole-2, 4-dicarboxylate?
    I don't know where "Diethyl - 3,5 - dimethyl - 1H - pyrrole - 2,4 - dicarboxylate" is. However, according to "Tiangong Wuwu", this chemical compound has not yet been developed, so it is said in ancient Chinese.
    In today's world, chemical substances are affected by many factors. The source of its raw materials, the ease of extraction, and the complexity of synthesis are all due to. If the raw materials are easily available, the method of synthesis will be convenient, and it will be inexpensive; if the raw materials are thin, the synthesis will be difficult, and high-precision skills and elegant tools will be required.
    It is also important to supply and demand. If the demand is low, the supply is low, and it must be low; on the contrary, if the supply is low in demand, it will decline automatically. And in different places, there are also differences due to the quality of the product and the quality of the product.
    If you want to know the market value of this product, you can change the supplier or check the chemical trading platform to get close to it.
    What are the storage conditions for Diethyl-3,5-dimethyl-1H-pyrrole-2, 4-dicarboxylate?
    Diethyl-3,5-dimethyl-1H-pyrrole-2,4-dicarboxylic acid ester is a kind of organic compound. Its storage conditions are quite important, which is related to the stability and quality of this compound.
    To properly store this compound, the first thing to pay attention to is the ambient temperature. It should be placed in a cool place, away from high temperature and open flame. Due to high temperature, the compound can easily undergo chemical reactions, which will damage its structure and properties. If the temperature is too high, or it may trigger reactions such as decomposition and polymerization, it will deteriorate and become unusable.
    For the second time, humidity is also a key factor. Avoid in a dry place to prevent moisture. Moisture or interaction with the compound, especially for those with hydrophilic groups, is more likely to cause adverse changes such as hydrolysis, affecting its purity and activity. Therefore, the storage place must have good moisture-proof facilities, such as using a desiccant to maintain a dry environment.
    Furthermore, this compound may be sensitive to light. Therefore, it should be stored in a dark place, and it can be stored in a brown bottle or a container wrapped in opaque materials to prevent photochemical reactions caused by light, resulting in degradation or structural changes of the compound.
    In addition, when storing, attention should also be paid to isolation. Avoid contact with oxidants, reducing agents, acids, alkalis and other substances, because of their active chemical properties, encounter with the above substances, or react violently, endangering safety and damaging their quality. It should be stored separately in a specific storage cabinet and marked for easy access and management.
    Proper storage of diethyl-3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate requires temperature control, dehumidification, protection from light and isolation, so as to maintain its long-term stability and maintain good chemical properties and quality for subsequent experiments, production and other purposes.