5-Ethoxycarbonyl-3,4-dimethylpyrrole

5-Ethoxycarbonyl-3,4-dimethylpyrrole is one of the organic compounds. Its main uses are quite extensive, and it is often used as a key intermediary in the field of organic synthesis.
The
cap has active reactivity due to its unique chemical structure, and can derive many organic compounds with different structures through various chemical reactions. For example, when building complex heterocyclic compound architectures, 5-ethoxycarbonyl-3,4-dimethylpyrrole can react with various nucleophiles and electrophiles to form carbon-carbon bonds and carbon-heteroatomic bonds, thus laying the foundation for the synthesis of compounds with specific biological activities or material properties.
Furthermore, it also plays an important role in the field of medicinal chemistry. This structural unit will be introduced into the synthesis path of many drug molecules. By chemically modifying and derivatizing it, it is expected to develop new drugs with excellent efficacy and mild side effects. Due to the characteristics of its structure, it may endow drugs with better bioavailability, targeting, and affinity with biological targets.
In addition, in the field of materials science, 5-ethoxycarbonyl-3,4-dimethylpyrrole participates in the synthesis of some polymers or functional materials, or has unique photoelectric properties, thermal stability, etc., showing potential application value in electronic devices, optical materials, etc.
Therefore, 5-ethoxycarbonyl-3,4-dimethylpyrrole has important uses in organic synthesis, drug development, materials science, etc., and has made great contributions to the development of various fields.

The synthesis of 5-ethoxycarbonyl-3,4-dimethylpyrrole is an important topic in the field of organic synthesis. The synthesis of this compound can be achieved according to different chemical pathways and reaction conditions.
First, it can be started from the basic raw material containing pyrrole ring. Using a specific substituted pyrrole as the substrate, ethoxycarbonyl is introduced through a suitable esterification reaction. In this process, a suitable esterification reagent, such as ethanol and the corresponding acylating agent, is selected to promote the esterification reaction under acid-catalyzed or base-catalyzed conditions. For example, using p-toluenesulfonic acid as the acid catalyst can make the reaction proceed smoothly under the condition of heating and refluxing.
Second, the construction of pyrrole ring can also be started. Through a multi-step reaction, a pyrrole ring precursor containing the desired substituent is formed first, and then subsequent modifications are carried out. For example, the Paal-Knorr reaction between 1,4-dicarbonyl compounds and ammonia or amine compounds occurs under acidic or basic conditions to construct a pyrrole ring structure. During the reaction, the substituents of the reactants can be cleverly adjusted to obtain a pyrrole ring containing 3,4-dimethyl. Subsequently, ethoxycarbonyl is introduced through appropriate functional group conversion.
Furthermore, the reaction path of metal catalysis is also a feasible method. With the help of transition metal catalysts, such as palladium, copper, etc., the coupling reaction of halogenated pyrrole derivatives with nucleophiles containing ethoxycarbonyl is catalyzed. This method requires careful selection of suitable ligands and reaction solvents to improve the selectivity and yield of the reaction.
There are many methods for synthesizing 5-ethoxycarbonyl-3,4-dimethylpyrrole, and each method has its own advantages and disadvantages. The ideal synthesis effect can only be achieved by carefully selecting the method according to the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, the purity and yield requirements of the target product, etc.

5-Ethoxycarbonyl-3,4-dimethylpyrrole is one of the organic compounds. Its physical properties are worth exploring.
First of all, its appearance, under normal temperature and pressure, is mostly solid or liquid, but the exact shape varies according to its purity and surrounding environment. If the purity is very high and the environment is stable, or it is a crystal clear solid with a certain crystalline form, it is regarded as a fine treasure; if it contains slightly impurities or the ambient temperature and humidity are different, it may also be a viscous liquid, flowing like grease.
Second and melting point and boiling point. The melting point is the critical temperature at which the substance changes from solid to liquid. The melting point of 5-ethoxycarbonyl-3,4-dimethylpyrrole is usually within a specific range due to intermolecular forces. The arrangement and interaction of atoms within the molecule require specific energy to break the lattice structure and melt into a liquid state. The boiling point is the temperature at which a liquid converts to a gas state. The boiling point of this compound is also determined by factors such as its intermolecular attractive force and molecular weight. Higher molecular weight and stronger intermolecular forces often increase the boiling point.
Furthermore, solubility is also an important physical property. In organic solvents such as ethanol and ether, 5-ethoxycarbonyl-3,4-dimethylpyrrole may have good solubility. The molecules of the organic solvent can form specific forces between the molecules of the compound, such as van der Waals force, hydrogen bond, etc., to help it disperse evenly in the solvent. However, in water, because of the non-polar characteristics of the molecular structure, the solubility is not good, and the polarity of water is difficult to match the molecules of the compound. The two are like oil and water, and it is difficult to blend.
In addition, density is also a property that cannot be ignored. Its density may be different from that of water. This property is of great significance in practical applications, such as separation, extraction, etc. If the density is greater than that of water, it will sink to the bottom of the water when stratifying; if it is less than water, it will float on the water surface, which can provide a basis for experimental operations.
To sum up, the physical properties of 5-ethoxycarbonyl-3,4-dimethylpyrrole are of critical value in both organic chemistry research and practical applications, which can help researchers gain a deeper understanding of their properties, and then provide strong support for related experiments and production.

5-Ethoxycarbonyl-3,4-dimethylpyrrole, this is an organic compound. Its chemical properties are profound, let me elaborate.
First of all, its physical properties are mostly liquid or solid at room temperature, and the color state varies depending on the purity, or colorless and transparent, or microstrip color. The melting boiling point depends on the intermolecular force. The presence of ethoxycarbonyl changes the intermolecular force, so the melting boiling point also has a corresponding value.
When it comes to chemical activity, the pyrrole ring is its core structure and is aromatic. The nitrogen atom on the pyrrole ring has a pair of unshared electron pairs and can participate in a variety of reactions. Such as the electrophilic substitution reaction, due to the high density of the pyrrole ring electron cloud, it is vulnerable to the attack of electrophilic reagents. The methyl group at the 3,4-position has a great influence on the reactivity and selectivity. The methyl group is the power supply group, which can further increase the electron cloud density of the pyrrole ring, which is more prone to electrophilic substitution, and the substitution position is also affected by it.
The characteristics of ethoxycarbonyl cannot be ignored. It can undergo hydrolysis reaction. Under acidic or basic conditions, the ester bond of ethoxycarbonyl breaks to form corresponding carboxylic acids and alcohols. Under alkaline conditions, the hydrolysis reaction is more rapid and thorough. This hydrolysis reaction has a wide range of uses in organic synthesis, whereby carboxyl functional groups can be introduced.
In addition, 5-ethoxycarbonyl-3,4-dimethylpyrrole can still participate in the condensation reaction. The carbonyl group of ethoxycarbonyl can be condensed with compounds containing active hydrogen to construct more complex organic structures.
In the reduction reaction, both the pyrrole ring and the ethoxycarbonyl group may become the reaction check point. Suitable reducing agents can partially or completely reduce the pyrrole ring, changing its aromaticity and chemical activity; the carbonyl group of ethoxycarbonyl can also be reduced to hydroxy or alcohol. In conclusion, 5-ethoxycarbonyl-3,4-dimethylpyrrole is rich in chemical properties and has important application value in the fields of organic synthesis and medicinal chemistry. It is a key intermediate for many organic reactions and can be derived from many useful compounds.

In today's world, it is not easy to know the price of 5-ethoxycarbonyl-3,4-dimethylpyrrole in the market. This compound may be used in many fields, such as organic synthesis and drug research and development. However, its price changes are often influenced by a variety of reasons.
First, the price of raw materials. If the raw materials required to prepare this compound are scarce and difficult to find, or the methods of picking and preparing are complicated, its price will be high, which will cause the price of 5-ethoxycarbonyl-3,4-dimethylpyrrole to rise.
Second, the method of preparation. If the synthesis method is delicate and complex, requires special reagents, equipment, or consumes a lot of energy, it will also increase the cost and increase the price.
Third, market supply and demand. If many industries have strong demand for it, but the output is limited, according to the reason of supply and demand, the price will go up; conversely, if there is little demand and excess supply, the price will fall.
Fourth, production scale. In large-scale production, due to economies of scale, the unit cost may be reduced and the price may be more affordable; in small-scale production, the opposite is true.
And the market conditions are changing rapidly, and the price often fluctuates over time. To know the exact price, you need to check the chemical products trading platform, consult relevant suppliers, or refer to recent market survey reports to get a more accurate number.