5 2 5 Difluorophenyl 3 4 Dihydro 2h Pyrrole
pyridine pyrrole pyrazine piperidine piperazine

5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole

    Specifications

    HS Code

    847866

    Chemical Formula C10H9F2N
    Appearance Solid (usually)
    Physical State Solid at room temperature
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Odor Odorless or very faint odor
    Stability Stable under normal conditions, may react with strong oxidizing agents

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    General Information
    Where to Buy 5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole in China?
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    Frequently Asked Questions

    As a leading 5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5- (2,5-difluorophenyl) -3,4-dihydro-2H-pyrrole?
    5- (2,5-diethylphenyl) -3,4-dihydro-2H-pyran, which is a key intermediate in organic synthesis. It has a wide range of uses in the field of medicine and can be used as an important raw material for a variety of drug synthesis. For example, when developing compounds with specific physiological activities, its structure can provide a basis for building the core skeleton of drug molecules, helping pharmaceutical chemists create new drugs with unique pharmacological effects.
    In the field of materials science, it can participate in the preparation of special polymer materials. With its special chemical structure, it can become a key monomer in the polymerization reaction, endowing polymer materials with unique properties such as special solubility, thermal stability or optical properties, so as to meet the performance requirements of high-end materials such as electronic devices and optical films.
    In the fragrance industry, 5- (2,5-diethylphenyl) -3,4-dihydro-2H-pyran can also play an important role. Because of its unique chemical structure, after appropriate chemical modification, it can produce a special aroma, providing the possibility for the formulation of novel and unique fragrance formulations. It is widely used in perfumes, food additives and other industries to add the aroma charm of products. Overall, it has important application value in many fields and is of great significance for promoting the development of related industries.
    What are the physical properties of 5- (2,5-difluorophenyl) -3,4-dihydro-2H-pyrrole
    5- (2,5-diethylamino) -3,4-dihydro-2H-pyrrole compounds have unique physical properties. Most of these compounds are crystalline or oily, with different stability at room temperature, some are sensitive to heat and light, and storage requires specific conditions.
    Its melting point varies depending on the molecular structure, containing polar groups and strong intermolecular forces, the melting point is relatively high; those with regular structure and good symmetry also have a high melting point. In terms of boiling point, it is related to molecular mass and polarity, with large mass and strong polarity, large intermolecular forces, and high boiling point. < Br >
    In terms of solubility, due to the diethylamino group, it has a certain alkalinity. In acidic solutions, it can form salts and improve the solubility in polar solvents such as water. However, overall, these compounds have good solubility in organic solvents such as ethanol, chloroform, and dichloromethane, but limited solubility in water.
    In terms of density, it is related to the type, quantity, and molecular stacking mode of constituent atoms. It is usually similar to the density of common organic solvents, and the density is slightly higher than that of water due to the mass distribution of atoms. In addition, some of these compounds have optical activities, such as chiral centers, which can rotate polarized light and have potential applications in the field of optical materials.
    These physical properties lay the foundation for their application in organic synthesis, drug development, and other fields. Understanding the properties can help to choose appropriate synthesis routes, separation and purification methods, and explore application directions.
    What is the chemical synthesis method of 5- (2,5-difluorophenyl) -3,4-dihydro-2H-pyrrole?
    To prepare 5- (2,5-diethylphenyl) -3,4-dihydro-2H-pyran, the following ancient method can be used.
    First take an appropriate amount of 2,5-diethylbenzaldehyde, which is the key raw material for the initiation of the reaction. Place it in a clean and dry reactor, which must be able to withstand a certain temperature and pressure, and have good sealing performance.
    Then, add an appropriate amount of allyl alcohol to the kettle. The amount of allyl alcohol needs to be precisely controlled. According to the stoichiometric ratio, when it reaches an appropriate ratio with 2,5-diethylbenzaldehyde, the reaction can proceed smoothly. < Br >
    Add an appropriate amount of acid catalyst, such as p-toluenesulfonic acid. The function of acid catalyst is to accelerate the reaction process and promote the rearrangement and combination of chemical bonds between molecules. When adding, it is best to add slowly and stir evenly, so that the catalyst can be fully dispersed in the reaction system to exert the best catalytic efficiency.
    After that, seal the reactor and slowly heat up. The heating process must be careful, so that the temperature can be slowly raised to a suitable reaction temperature, generally speaking, between 60 and 80 degrees Celsius. This temperature range can not only ensure the reaction rate, but also avoid the excessive occurrence of side reactions. During the heating process, the reaction mixture is continuously stirred to make the components fully contact and the reaction is more uniform. < Br >
    After several hours of reaction, when the various indicators of the reaction system show that the reaction has reached the expected level, the heating is stopped. However, at this time, the product still contains many impurities, and subsequent separation and purification steps are required.
    The method of reduced pressure distillation can be used first, and the difference in boiling points of different substances can be used to preliminarily separate the target product and some low boiling point impurities. Collect the fraction in a specific boiling point range, which is the preliminary enrichment of 5- (2,5-diethylphenyl) -3,4-dihydro-2H-pyran.
    Then, the fraction is further purified by column chromatography. Select suitable stationary and mobile phases to effectively separate the target product from the remaining impurities in the chromatographic column. Collect the pure target product fraction and dry it to obtain pure 5- (2,5-diethylphenyl) -3,4-dihydro-2H-pyran. The whole process requires fine operation and attention to the condition control of each link in order to obtain satisfactory results.
    What is the market outlook for 5- (2,5-difluorophenyl) -3,4-dihydro-2H-pyrrole?
    What is the market prospect of 5- (2,5-diethylphenyl) -3,4-dihydro-2H-pyran? Let me describe it in the style of "Tiangong Kaiwu".
    Now looking at this product, it may have unique uses in chemical fields. 2,5-diethylphenyl is combined with 3,4-dihydro-2H-pyran structure, or it has different chemical properties. In the field of organic synthesis, it can be used as a key intermediate, if it is a good material for craftsmen to construct complex organic molecules.
    It is in the field of medicinal chemistry, or the basis for the creation of new pharmaceuticals. Starting with it, through various reactions, compounds with special pharmacological activities may be derived, such as the search for good medicine, which opens up a new way for the treatment of diseases.
    In material science, or because of its structural characteristics, it can participate in polymerization reactions to obtain polymers with specific properties. Such as clever workmanship, it can endow materials with unique mechanical, thermal or optical properties, which can be used in high-tech industries such as electronics and optics.
    However, its market prospects are also influenced by many factors. First, the difficulty and cost of the preparation process. If the process is complicated and the cost is high, if the road is blocked, its promotion and application will be limited. Second, the competition of similar substitutes. Chemical products often have similar functions. If there are better substitutes, their market space will be squeezed. Third, the change of market demand. With the advance of science and technology, the needs of the industry are changing rapidly, and whether it can meet the emerging needs is also the key.
    In summary, although 5- (2,5-diethylphenyl) -3,4-dihydro-2H-pyran has potential value, if you want to open up a broad market prospect, you need to break the preparation problem, deal with competition, and adapt to changes in demand, so that you can hope to swim downstream like a boat and swim smoothly in the sea of the market.
    What are the precautions for using 5- (2,5-difluorophenyl) -3,4-dihydro-2H-pyrrole?
    5- (2,5-diethylphenyl) -3,4-dihydro-2H-pyran In the process of use, the following things must be paid attention to:
    First, it concerns its chemical properties. This compound has specific chemical activity and reaction characteristics. When storing, it should be kept away from strong oxidants, strong acids, strong bases and other substances. Because its structure contains unsaturated bonds and special substituents, it encounters strong oxidants, or triggers violent oxidation reactions, causing combustion or even explosion; in case of strong acids, strong bases, or hydrolysis, rearrangement and other reactions, the structure and purity of the substance are damaged.
    Second, it involves the operating environment. It should be operated in a well-ventilated place. Because it may evaporate certain irritating and toxic vapors, good ventilation can disperse the vapors in time, reduce the concentration in the air, and protect the health of the operator. During operation, it is also necessary to avoid open flames and hot topics. This compound is flammable. In case of open flames and hot topics, it is flammable and poses a fire hazard.
    Third, about personal protection. Operators must wear appropriate protective equipment. Protective work clothes are required to prevent skin contact; protective gloves are worn to avoid direct contact and skin absorption or irritation; protective glasses and gas masks are worn to protect the eyes and respiratory tract from steam damage.
    Fourth, for storage requirements. Should be stored in a cool, dry and well-ventilated warehouse. Keep away from fire and heat sources, and the storage temperature should not exceed 30 ° C. Keep the container sealed to prevent moisture absorption and volatilization. And it should be stored separately from oxidizing agents, acids, and bases, and should not be mixed to prevent accidental reactions.
    In short, when using 5- (2,5-diethylphenyl) -3,4-dihydro-2H-pyran, all details should be carefully treated, and the operation and storage should be strictly in accordance with the specifications to ensure the safety of personnel, experiments, and smooth production.