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What is the chemical structure of 4-Ethyl-3-methyl-5-oxo-N-phenethyl-2H-pyrrole-1-carboxamide?
This is the naming of organic compounds, following the naming rules of organic chemistry, and its chemical structure can be analyzed. In "4-ethyl-3-methyl-5-oxo-N-phenethyl-2H-pyrrole-1-formamide", "2H-pyrrole" is the basic structure, which is a five-membered heterocycle containing a nitrogen atom, where "2H" indicates that the hydrogen atom is located at position 2. At position 1 of the pyrrole ring, the "formamide" group is connected, which is an amide structure, that is, -CONH -, and the nitrogen atom of the amide group is connected to the phenethyl group (the group formed by the removal of a hydrogen atom from phenethane). At position 3 of the pyrrole ring, there is a methyl group (-CH < unk >), position 4 is an ethyl group (-CH < unk > CH < unk >), and position 5 is an oxo group, which forms a carbonyl group (C = O). It can be seen that this compound has a pyrrole ring as the core and a variety of substituents at different positions, which together form a specific chemical structure. Such structures have unique chemical properties and potential applications in the fields of organic synthesis and medicinal chemistry, or due to the characteristics of pyrrole rings and related substituents.
What are the physical properties of 4-Ethyl-3-methyl-5-oxo-N-phenethyl-2H-pyrrole-1-carboxamide?
4-Ethyl-3-methyl-5-oxo-N-phenethyl-2H-pyrrole-1-formamide, this is an organic compound. Its physical properties, let me tell you in detail.
First, the appearance is at room temperature, or in the form of white to off-white crystalline powder, which is delicate and uniform, just like the snow that falls in the early winter, pure and simple.
As for the melting point, after rigorous determination, it is about a specific temperature range. This temperature range is the key node of its transition from solid to liquid state, just like the hub of physical state change, precise and orderly. The characteristic of this melting point is of great significance for the identification and purification of this compound, like a beacon guiding the maze.
Solubility is also one of the important physical properties. In common organic solvents, such as ethanol and dichloromethane, it exhibits a certain solubility. In ethanol, like snowflakes, it merges into streams and slowly disperses and dissolves to form a uniform solution. This property lays the foundation for its application in organic synthesis and drug research and development, just like the foundation for building high-rise buildings.
Its density also has a specific value, which reflects the quality of its unit volume. It is like a scale for measuring the compactness of substances. It is indispensable in chemical production and quality control. It precisely controls the quality of products.
In addition, the stability of this compound is also worthy of attention. Under normal environmental conditions, it is relatively stable. However, under extreme conditions such as high temperature, strong acid, and strong alkali, its structure or changes, just like the flower of a greenhouse, and it is difficult to resist the invasion of severe climate. This stability characteristic determines the conditions for its storage and use, and it needs to be properly cared for in order to maintain its inherent characteristics and efficacy.
In summary, the many physical properties of 4-ethyl-3-methyl-5-oxo-N-phenethyl-2H-pyrrole-1-formamide are related to each other, and together build its unique material characteristics, paving the way for its application in many fields, and also providing important clues and basis for researchers to deeply explore its mysteries.
What are 4-Ethyl-3-methyl-5-oxo-N-phenethyl-2H-pyrrole-1-carboxamide application fields?
4-Ethyl-3-methyl-5-oxo-N-phenethyl-2H-pyrrole-1-formamide, this is an organic compound. Its application field is quite extensive, in the field of medicine, or has potential medicinal value. Doctors have been exploring various medicinal stones since ancient times to treat diseases. This compound may be further studied and used to create new drugs, or can act on specific disease targets, bringing good news to patients.
In the field of materials science, or can be used to prepare materials with special properties. In ancient times, skilled craftsmen created various utensils with unique skills, and today's materials science also pursues excellence. This compound may be used as a key component in the construction of special structural and functional materials, making the material have unique electrical, optical or mechanical properties, and is used in electronic equipment, optical instruments, etc.
In the field of agriculture, or has a positive effect on plant growth and pest control. The ancient people cultivated, focusing on the right time and location and crop conservation. This compound may have been developed to become a plant growth regulator, help crops thrive, or can be used as a new pesticide ingredient to resist pest attacks and ensure crop harvests.
In the field of scientific research, or as an important research tool and model compound. Scholars often study various substances to explore their properties and reaction mechanisms. This compound's unique structure may provide new ideas for multidisciplinary research in chemistry, biology, etc., and help researchers expand their cognitive boundaries, contributing to scientific development.
What is 4-Ethyl-3-methyl-5-oxo-N-phenethyl-2H-pyrrole-1-carboxamide synthesis method?
To prepare 4-ethyl-3-methyl-5-oxo-N-phenethyl-2H-pyrrole-1-formamide, the following ancient method can be used.
First take appropriate starting materials, such as compounds containing pyrrole structure, whose structure may already have some of the desired groups for the target molecule. Pyrrole derivatives with suitable substituents can be selected. If the substituents are related to the 4-ethyl, 3-methyl, and 5-oxo groups of the target product, some steps can be omitted. For example, if there is a pyrrole derivative with a group that can be converted into ethyl and methyl at the corresponding position, and a functional group that can be oxidized to carbonyl, it can be used.
For the introduction of 4-ethyl, a suitable halogenated ethane reagent can be found, and under the action of appropriate basic conditions and catalysts, it can be introduced by nucleophilic substitution reaction. The alkaline environment can help the leaving group of halogenated ethane to leave, and the nucleophilic reagent attacks the specific position on the pyrrole ring to complete the introduction of ethyl. The base used can be selected from potassium carbonate, potassium tert-butanol, etc., depending on the reaction conditions and substrate activity. The catalyst can also be selected as a phase transfer catalyst, such as tetrabutylammonium bromide, to promote the reaction.
As for the introduction of 3-methyl, the method of imitating the introduction of ethyl can be completed by using a halogenated methane reagent in a similar basic catalytic environment. However, this step needs to pay attention to the reaction selectivity to avoid methylation at other check points.
5-oxo group, if the starting material does not have a suitable oxidizable group, consider oxidizing the corresponding alcohol or aldehyde group to carbonyl with an oxidizing agent. For example, oxidizing the alcohol to carbonyl with Jones reagent (chromic acid-sulfuric acid solution), or oxidizing the aldehyde to carbonyl with a mild oxidizing agent such as Dice-Martin, and has little effect on other sensitive groups.
N-phenethyl moiety, phenethylamine can be used to react with pyrrole-1-formyl halide containing suitable leaving groups. Formalyl halide can be prepared by reacting the corresponding pyrrole-1-carboxylic acid with halogenating reagents such as thionyl chloride. The amino group of phenethylamine attacks the carbonyl carbon of the formyl halide, and the halogen ions leave to form an amide bond, thereby introducing N-phenethyl.
After each step of the reaction, it needs to be separated and purified by methods such as column chromatography, recrystallization, etc., to obtain pure 4-ethyl-3-methyl-5-oxo-N-phenethyl-2H-pyrrole-1-formamide products. The whole synthesis process needs to carefully control the reaction conditions, pay attention to the selectivity and yield of each step, and then it can be obtained smoothly.
How safe is 4-Ethyl-3-methyl-5-oxo-N-phenethyl-2H-pyrrole-1-carboxamide?
4-Ethyl-3-methyl-5-oxo-N-phenethyl-2H-pyrrole-1-formamide, this is an organic compound. In terms of its safety, it needs to be carefully examined from multiple aspects.
First physical and chemical properties. The state, melting point, boiling point, solubility, etc. of this substance are all related to the safety of use. If it is a solid, it needs to be prevented from the risk of inhalation caused by dust; if it is dissolved in a specific solvent, the flammable and volatile properties of the solvent also need to be considered. For example, if it is easily soluble in flammable organic solvents, it will be at risk of fire when used in an open flame or hot topic.
Re-examine stability. Under normal storage and use conditions, this compound should have good stability. In case of light, heat, moisture or specific chemicals, it may decompose and polymerize. If some compounds decompose toxic gases when heated, it will not only endanger the human body, but also pollute the environment.
Toxicological data are also critical. In terms of acute toxicity, if the value of the oral, percutaneous or inhaled half lethal dose (LD50 or LC50) is low, it indicates strong toxicity, and a small amount of exposure can cause serious injury or even death. Long-term chronic toxicity cannot be ignored. Long-term low-dose exposure may cause organ damage, carcinogenesis, teratogenesis and other consequences. For example, long-term exposure to some compounds can cause liver and kidney damage, or increase the risk of cancer.
Environmental impact is also a key point. How degradable is it in the environment? If it is difficult to degrade, it is easy to accumulate in the environment and harm the ecology. And its toxicity to aquatic organisms and terrestrial organisms is related to ecological balance. If it is highly toxic to aquatic organisms such as fish and algae, it will destroy aquatic ecosystems.
To fully understand the safety of 4-ethyl-3-methyl-5-oxo-N-phenethyl-2H-pyrrole-1-formamide, it is necessary to study the above aspects in detail, and strictly follow safety operating procedures and regulatory requirements to ensure safety during use and storage, and minimize risks.