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What is the main application field of 4- (9H-fluorene-9-methoxycarbonylamino) -1-methyl-1H-pyrrole-2-carboxylic acid
4- (9H-xanthene-9-methoxycarbonyloxycarbonyl) -1-methyl-1H-indazole-2-carboxylic acid, this compound has important applications in the field of medicinal chemistry.
In drug development, it is often used as a key intermediate. Due to its unique chemical structure, it can participate in a variety of organic synthesis reactions and help build complex molecular structures with specific pharmacological activities. For example, in the creation process of some new anti-tumor drugs, it can form compounds with the ability to target specific targets of tumor cells by condensation and substitution with other active groups. By modifying and modifying its structure, it can adjust the properties of lipid solubility, water solubility and affinity with targets of drugs, thereby improving the efficacy of drugs and reducing toxic and side effects.
In the field of materials science, the compound also shows certain application potential. Because some groups in its structure may have special optical and electrical properties, it can be used to develop new organic optoelectronic materials. For example, in the exploration of organic Light Emitting Diode (OLED) materials, introducing it into the material structure may improve the properties of materials such as luminous efficiency and stability, providing a new way to prepare high-performance display devices. At the same time, in terms of sensor materials, based on its possible selective recognition and response characteristics to certain specific substances, it is expected to develop highly sensitive and highly selective chemical sensors for the detection of environmental pollutants, biomarkers, and so on.
What are the physicochemical properties of 4- (9H-fluorene-9-methoxycarbonylamino) -1-methyl-1H-pyrrole-2-carboxylic acids
4- (9H-carboxylaminocarbamido) -1-methyl-1H-pyrazole-2-carboxylic acid is a complex organic compound. Its physicochemical properties are very important for its application in various fields.
Looking at its physical properties, under normal circumstances, this compound may be in a solid state with a specific melting point and boiling point. The melting point is the temperature at which a substance changes from solid to liquid state, and the boiling point is the temperature at which it changes from liquid to gas state. The two are determined by the intermolecular force. The strong intermolecular force makes the melting point and boiling point high. The molecular structure of the compound makes the intermolecular force unique, which in turn determines its melting boiling point. < Br >
Solubility is also a key physical property. In different solvents, its solubility varies. In polar solvents, such as ethanol and water, if the molecule has polar groups and forms hydrogen bonds or other interactions with the solvent molecules, the solubility is good; in non-polar solvents, such as benzene and carbon tetrachloride, if the molecule has strong non-polarity, the solubility is poor.
On its chemical properties, this compound contains a variety of functional groups, such as pyrazole rings, carboxyl groups, aminocarbamide groups, etc. The carboxyl group is acidic and can neutralize with bases to form corresponding carboxylate and water. The nitrogen atom in carbamoyl urea group has a lone pair of electrons, which can be used as a nucleophilic reagent to participate in nucleophilic substitution reactions and react with electrophilic reagents such as halogenated hydrocarbons to form new carbon-nitrogen bonds or other chemical bonds. The pyrazole ring also has certain chemical activity and can participate in the substitution reaction on the ring. Under suitable conditions, the hydrogen atom on the ring can be replaced by other groups.
The physical and chemical properties of this compound are closely related to its structure, laying the foundation for its application in organic synthesis, drug research and development, etc. In organic synthesis, more complex compounds can be prepared by virtue of its chemical activity; in drug research and development, physical properties such as solubility are related to drug absorption, and chemical properties can participate in specific physiological and chemical reactions and play pharmacological roles.
What is the synthesis method of 4- (9H-fluorene-9-ylmethoxycarbonylamino) -1-methyl-1H-pyrrole-2-carboxylic acid?
To prepare 4- (9H-xanthoxy-9-oxycarbonylamino) - 1-methyl-1H-pyrazole-2-carboxylic acid, please refer to the method of "Tiangong Kaiwu", which is detailed in the ancient method as follows:
The choice of starting material is very important. When a compound with a specific structure is used as a base, the target product can be obtained after multiple steps of delicate transformation.
The first step is to select a suitable compound containing xanthoxy-ton structure. This compound needs to have a reactive active group at a specific check point. With the action of a reagent, under the reaction conditions of delicate regulation, such as precise temperature control and solvent selection, the substitution reaction occurs. In this process, the active group is cleverly combined with the reagent to introduce the required oxycarbonyl amino group to form the key intermediate.
Then, the compound containing methyl and pyrazole structures is taken to meet the above intermediates. After condensation reaction, the connection between the pyrazole ring and the xanthene structure is constructed. In this step of the reaction, attention should be paid to the acid-base balance of the reaction environment, because it has a profound impact on the reaction process and the purity of the product. Through careful adjustment, the reaction is promoted to proceed smoothly and another important intermediate is formed.
At the end of the final step, a specific carboxylation reaction is applied to the obtained intermediate. Select the appropriate carboxylation reagent and introduce the carboxyl group at the target check point under suitable reaction conditions, resulting in 4- (9H-xanthon-9-yloxycarbonyl amino) -1-methyl-1H-pyrazole-2-carboxylic acid. The purity and yield of this product are related to the precise control of each step of the reaction. From the balance of material ratio to the determination of reaction time, it is necessary to be careful in order to achieve the desired synthetic effect.
What is the price range of 4- (9H-fluorene-9-ylmethoxycarbonylamino) -1-methyl-1H-pyrrole-2-carboxylic acid in the market?
I haven't heard the exact price of "4- (9H-Ka-9-ylcarbamoyl carbamoyl) -1-methyl-1H-pyrazole-2-carboxylic acid" on the market. However, if you want to know the price range of this product on the market, you should follow various channels.
First, ask the chemical raw material trading platform. In today's world, many chemical products are traded on the online platform. The prices of the general products listed above may have the price of "4- (9H-Ka-9-ylcarbamoyl carbamoyl) -1-methyl-1H-pyrazole-2-carboxylic acid". You can compare the quotations of multiple suppliers to clarify their approximate price range.
Second, visit the chemical raw material supplier. You can find a well-known supplier in the industry, call or interview, and inquire about the price of this product. Different suppliers may have different prices due to different raw material costs, production processes, and production scales. Ask a few more to get a more accurate price range.
Third, refer to the price of congeneric products. If you can't find the exact price of this product, you can test the price of products similar to its structure and use to infer its price range. However, this is only a rough guess, or there is a difference with the actual price.
In summary, to know the price range of "4- (9H-ka-9-ylaminoformyl) -1-methyl-1H-pyrazole-2-carboxylic acid" in the market, it is necessary to search for information widely and comprehensively consider various factors to obtain a more accurate number.
What are the storage conditions for 4- (9H-fluorene-9-ylmethoxycarbonylamino) -1-methyl-1H-pyrrole-2-carboxylic acid?
4- (9H-Tie-9-methoxycarbonyl-oxy-carbonyl) -1-methyl-1H-pyrrole-2-carboxylic acid is an organic compound, and its storage conditions are not directly recorded in Tiangong Kaiwu, but it can be deduced from the wisdom of the ancients on the preservation of similar substances and modern chemical knowledge.
Ancient collection, heavy dry, cool, and protected from light. For these things, a dry environment is essential. Because it contains many groups that are easy to react with water, if the environment is humid, water molecules are easy to attack, causing structural changes and property changes. Such as ancient medicine, often placed in a lime tank to absorb moisture, this thing may be similar, choose a sealed container, put desiccant inside, to prevent moisture dissolution.
In a cool place, avoid high temperature. High temperature can increase molecular activity, promote the decomposition of this compound or cause side reactions. There is a method of hiding ice in ancient times, and it is difficult to reduce room temperature in summer. Although it is difficult to use this thing for large-scale storage, it can be used. Choose a cool warehouse and control the room temperature within an appropriate range.
Avoid light and do not ignore it. Light is energy, which can cause photochemical reactions, which can break chemical bonds and change the structure of this compound. Ancient people used cloth to cover windows and protect them from light. This thing may be stored in dark containers such as brown bottles to reduce the effect of light. < Br >
In addition, anti-oxidation is also crucial. There are oxidizable parts in its structure, which should be stored in oxygen isolation. The ancient oil sealing method used oil to isolate the air, but now it can be protected by inert gas. Nitrogen and other gases are filled in the storage container to prevent it from connecting with oxygen, ensuring its chemical properties are stable and achieving good storage effect.