4-(2-((3-ethyl-4-methyl-2-oxo-pyrrolin-1-yl)carboxamido)ethyl)benzenesulfonamide)

The Chinese name of this compound is 4- [2- ((3-ethyl-4-methyl-2-oxo-pyrrolidine-1-yl) formamido) ethyl] benzenesulfonamide. Its chemical structure can be explained as follows:
- The main structure is benzenesulfonamide, that is, a sulfonamide group (-SO ² NH ²) is connected to the benzene ring. A substituent is connected to the No. 4 position of the benzene ring. < Br > - The substituent is 2- ((3-ethyl-4-methyl-2-oxo-pyrrolidine-1-yl) formamido) ethyl. This substituent is linked by ethyl, one end of which is connected to the benzene ring No. 4 position, and the other end is connected to the amide structure.
- The acyl moiety of the amide structure is connected to a 3-ethyl-4-methyl-2-oxo-pyrrolidine-1-yl. The pyrroline ring is a five-membered nitrogen-containing heterocyclic ring, with a carbonyl group (C = O) at position 2, a ethyl group at position 3, and a methyl group at position 4.
The structure of this compound is expressed in ancient Chinese, but it can be said: "There is a benzene ring, on which the sulfonamide group is located at the four positions. There is also a substituted group, which is based on the four positions of the benzene ring. This group is linked to ethyl as a chain, with benzene at one end and amide at the other end. The acyl group of the amide is connected to a five-membered nitrogen-containing heterocyclic ring, and there is a carbonyl group at the second position of the ring. It is ethyl at three positions, and methyl at four positions." In this way, the chemical structure of

4- (2- ((3-ethyl-4-methyl-2-oxo-pyrroline-1-yl) formamido) ethyl) benzenesulfonamide, which is an organic compound. To clarify its physical properties, the following numbers can be used.
First words Appearance and properties, this compound is either solid or powder state, which often depends on its intermolecular forces and crystallization habits. Looking at the normal state of organic compounds, those containing many polar groups such as amide groups and sulfonamide groups are more likely to form solid states, because these groups can cause hydrogen bonds between molecules, increase the attractive force between molecules, and promote their polymerization into solid states.
times, melting point and boiling point, intramolecular hydrogen bonds and van der Waals forces have a great influence on them. Amide groups and sulfonamide groups can form intramolecular and intermolecular hydrogen bonds, causing the melting point to rise. And its boiling point, in addition to hydrogen bonding, the molecular weight and molecular shape are also key. This compound has a certain molecular weight and a non-polar symmetry in structure, so the boiling point should not be low. < Br >
The other is solubility. Due to the presence of polar groups, it theoretically has a certain solubility in polar solvents such as methanol, ethanol, and water (if the hydrogen bond is strong). However, the hydrocarbon group part is hydrophobic, so in non-polar solvents such as hexane and benzene, the solubility may be limited.
Also known as density, according to its molecular composition and mass, it can be inferred that its density is different from that of water. The mass and spatial arrangement of carbon, hydrogen, nitrogen, oxygen, sulfur and other atoms in the molecule determine its density.
The physical properties of this compound depend on the interaction of various groups in its molecular structure. The above discussion is only based on its structural characteristics, and the exact properties need to be determined experimentally.

This compound is called 4- [2- [ (3-ethyl-4-methyl-2-oxo-pyrrolidine-1-yl) formamido] ethyl] benzenesulfonamide. However, in the ancient process technology, agriculture and handicraft knowledge system involved in "Tiangong Kaiwu", it is difficult to find traces of application of this fine compound of modern organic chemistry.
Gai "Tiangong Kaiwu" was written in Chongzhen ten years in the Ming Dynasty, when chemical science had not yet evolved to the realm of being able to recognize and synthesize such complex organic compounds. The book details the traditional farming, textiles, ceramics, smelting, papermaking, salt making and other skills, and the materials used are mostly common natural things, such as hardware ore, cotton and linen silk, grass, soil and stone, etc. The synthesis of organic compounds has not yet appeared in the field of vision of the ancients.
Today's 4- [2 - [ (3-ethyl-4-methyl-2-oxo-pyrrolidine-1-yl) formamido] ethyl] benzenesulfonamide is mostly used in modern pharmaceutical research and development, organic synthesis chemistry experiments, or as an intermediate in specific materials science fields. Its complex structure and synthesis require the support of modern advanced chemical theory and experimental technology, which is beyond the reach of ancient technological knowledge, and is not relevant to the category described in "Tiangong Kaiwu".

To prepare 4 - {2 - [ (3-ethyl-4-methyl-2-oxo-pyrrolidine-1-yl) formamido] ethyl} benzenesulfonamide, there are several methods.
First, the corresponding benzenesulfonyl chloride can be reacted with an amino-containing precursor. First take a suitable benzenesulfonyl chloride, and under mild reaction conditions, such as in an organic solvent, meet with ethyl amines containing (3-ethyl-4-methyl-2-oxo-pyrrolidine-1-yl) formamide group. This reaction requires controlling the temperature and the ratio of the reactant to promote the smooth condensation of the two to form the target product. Excessive temperature or unbalanced ratio may cause side reactions to breed, affecting the purity and yield of the product.
Second, the construction of pyrrolidine ring can be started. First, with suitable raw materials, such as amines and carbonyl compounds containing specific substituents, under the catalysis of acids or bases, the cyclization reaction generates a 3-ethyl-4-methyl-2-oxo-pyrroline structure. Subsequently, the ring structure is connected to the ethyl derivative containing benzenesulfonamide group. During the connection steps, the reaction reagents and conditions need to be carefully selected, or assisted by coupling agents to ensure accurate bonding.
Third, a stepwise synthesis strategy can also be adopted. First synthesize the intermediate containing benzenesulfonamide group, and then gradually introduce the side chain containing pyrroline ring on it. In this process, each step of the reaction needs to be carefully planned, and the reaction conditions such as solvent, temperature, catalyst, etc. are strictly controlled to ensure the efficiency and accuracy of each step of the reaction. Finally, the multi-step reaction gathers to obtain 4 - {2 - [ (3-ethyl-4-methyl-2-oxo-pyrrolidine-1-yl) formamido] ethyl} benzenesulfonamide. Each method has its own advantages and disadvantages, and the actual operation needs to be weighed according to factors such as raw material availability, cost, and product purity requirements.

4- (2- ((3-ethyl-4-methyl-2-oxo-pyrrolidine-1-yl) formamido) ethyl) benzenesulfonamide, according to ancient principles, is related to various hidden dangers and side effects.
Look at its chemical structure, including the parts of pyrrolidine and benzenesulfonamide. The ring of pyrrolidine has specific activities, and its side chain groups may induce various physiological responses. In organisms, or interact with biological macromolecules such as proteins and enzymes, if it binds to key enzymes, or disrupts the normal function of enzymes, such as metabolism-related enzymes, causing metabolic imbalance, toxin accumulation in the body, and energy metabolism disorders.
The part of benzenesulfonamide often has pharmacological activity, but it may also be involved in adverse reactions. Past studies have shown that compounds containing this structure may stimulate the gastrointestinal tract, causing nausea, vomiting, and abdominal pain, which may affect the normal physiology of gastrointestinal mucosal cells or change the function of mucosal barrier. Or disturb the immune balance of the body, cause immune overstimulation or depression, and disrupt immune signaling pathways due to binding to receptors on the surface of immune cells.
Furthermore, the metabolites of this compound may also have latent risk. After metabolism in the body, its structure changes, and the newly formed substances may be more toxic or difficult to excrete, accumulating in the body, damaging the function of organs, such as liver and kidney. Liver and kidney are important organs for metabolism and excretion. If they are affected, the overall homeostasis of the body is endangered.
And the absorption and distribution characteristics of the compound are also related to its potential harm. If it is easy to pass through the blood-brain barrier and enter the central nervous system, or disturb the balance of neurotransmitters, causing neuropsychiatric symptoms such as insomnia, anxiety, cognitive impairment, etc.
In summary, 4- (2- ((3-ethyl-4-methyl-2-oxo-pyrrolidine-1-yl) formamido) ethyl) benzenesulfonamide may have pharmacological potential, but there are many potential risks and side effects. When applying, we should carefully review and exercise caution to ensure safety.