4 2 2 Difluoro 1 3 Benzodioxol 4 Yl 1h Pyrrole 3 Carbonitrile
pyridine pyrrole pyrazine piperidine piperazine

4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1h-pyrrole-3-carbonitrile

    Specifications

    HS Code

    422461

    Chemical Formula C12H6F2N2O2
    Molar Mass 248.185 g/mol
    Appearance Solid (predicted)
    Boiling Point Predicted to be high due to strong intermolecular forces
    Melting Point Predicted to be relatively high
    Solubility In Water Low solubility, as it is non - polar (predicted)
    Solubility In Organic Solvents Good solubility in non - polar organic solvents like dichloromethane (predicted)
    Density Predicted based on similar compounds
    Polarity Moderate polarity due to the presence of polar groups and benzene ring
    Stability Stable under normal conditions (predicted)

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    General Information
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    Frequently Asked Questions

    As a leading 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1h-pyrrole-3-carbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 4- (2,2-difluoro-1,3-benzodioxane-4-yl) -1H-pyrrole-3-formonitrile
    4- (2,2-diethyl-1,3-benzodioxacyclopentene-4-yl) -1H-pyrrole-3-acetic acid has a wide range of main uses.
    In the field of medicine, this compound is often the key raw material for the creation of new drugs. Due to its special chemical structure, it can exhibit a variety of biological activities. It may interact with specific biological targets to regulate physiological functions and treat diseases. For example, in the treatment of neurological diseases, drugs for nerve cell protection and neurotransmitter regulation may be developed, which is expected to bring new opportunities for the treatment of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.
    In the field of materials science, it also has its application. By virtue of its own structural characteristics, it may be able to participate in the preparation of materials with special properties. For example, it is used in the preparation of optoelectronic device materials, using its unique electronic structure to make the material exhibit excellent optical and electrical properties, and may have potential applications in organic Light Emitting Diode (OLED), solar cells and other fields to help improve the performance and efficiency of optoelectronic devices.
    Furthermore, in the field of chemical synthesis, this substance is often used as an important intermediate. Organic synthesis chemists can modify and modify their structures to derive many compounds with different structures, expand the types and functions of organic compounds, and lay the foundation for further scientific research and industrial applications.
    In summary, 4- (2,2-diethyl-1,3-benzodioxane-4-yl) -1H-pyrrole-3-acetic acid has important value in many fields such as medicine, materials science and chemical synthesis, and opens up broad prospects for many research and applications.
    What are the synthesis methods of 4- (2,2-difluoro-1,3-benzodioxane-4-yl) -1H-pyrrole-3-formonitrile
    To prepare 4- (2,2-diethyl-1,3-naphthalene-heterocyclopentene dioxide-4-yl) -1H-pyrrole-3-acetic acid, the following methods can be used.
    One is the method of nucleophilic substitution. First, take the naphthalene-heterocyclopentene dioxide halide containing the appropriate substituent, and the nucleophilic reagent containing the pyrrole structure, in a suitable solvent, such as N, N-dimethylformamide (DMF) or dimethyl sulfoxide (DMSO), under the catalysis of a base, such as potassium carbonate or sodium carbonate, the nucleophilic substitution reaction occurs between the two to form a key intermediate. This intermediate is then suitably carboxylated, such as with carbon dioxide under specific conditions, or with halogenated acetate after hydrolysis, to obtain the target product.
    The second is the way of cyclization reaction. The chain compound with the appropriate functional group is used as the starting material, and the prototype of the naphthalene and heterocyclopentene dioxide part and pyrrole ring is constructed through a series of reactions. For example, the functional groups interact with each other through an intra-molecular ring-closing reaction. The commonly used reaction conditions depend on the characteristics of the raw materials, or involve acidic or basic catalysts, which promote cyclization under conditions such as heating. After cyclization, the resulting product is suitably modified, and an acetic acid group is introduced to achieve the synthesis of the target product.
    The third is the method of using transition metal catalysis. Select suitable transition metal catalysts, such as palladium, copper, etc., to catalyze the coupling reaction of substrates containing different functional groups. For example, in the presence of transition metal catalysts and ligands, in the presence of transition metal catalysts and ligands, in the presence of suitable solvents and bases, the coupling reaction occurs between halides containing naphthalene and heterocyclopentene dioxide and compounds containing pyrrole and acetate precursors, and the target product 4 - (2,2 - diethyl - 1,3 - naphthalene and heterocyclopentene dioxide - 4 - yl) - 1H - pyrrole - 3 - acetic acid is obtained directly or after several steps of conversion. Each method has its own advantages and disadvantages, and the actual operation needs to be comprehensively selected according to factors such as the availability of raw materials, cost and difficulty of reaction conditions.
    What are the physical and chemical properties of 4- (2,2-difluoro-1,3-benzodioxane-4-yl) -1H-pyrrole-3-formonitrile
    4- (2,2-diethyl-1,3-benzodioxane-4-yl) -1H-pyrrole-3-acetic acid is an organic compound with specific physical and chemical properties.
    Looking at its structure, it contains benzodioxane and pyrrole rings. In terms of physical properties, it is usually a solid, with a certain melting point due to intermolecular forces. And because the structure contains polar groups, it has good solubility in organic solvents and limited solubility in water.
    In terms of chemical properties, benzo heterocyclopentene dioxide has a stable structure, but the nitrogen atom on the pyrrole ring has lone pair electrons, which shows a certain alkalinity and can react with acids to form salts. Its pyrrole ring is also aromatic and can undergo electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. The substituents may mainly fall in the active site of the pyrrole ring. In addition, the carboxyl group in the molecule can participate in the esterification reaction and form esters with alcohols under acid catalysis; the carboxyl group can also react with bases to form salts, showing acidity. Due to the presence of multiple different structural units, this compound can participate in a variety of organic reactions and has potential application value in the field of organic synthesis.
    What is the market price of 4- (2,2-difluoro-1,3-benzodioxane-4-yl) -1H-pyrrole-3-formonitrile?
    I think what you said is about the market price of "4- (2,2-diethyl-1,3-naphthalene and heterocyclopentene dioxide-4-yl) -1H-pyrrole-3-acetic acid". However, this is a very common thing, and its price is difficult to determine.
    The market price of the husband often changes for many reasons. First, it is difficult to produce. If its preparation requires difficult processes and rare raw materials, the price will be high. The preparation of this compound, or the complex organic synthesis reaction, requires strict requirements on the purity of raw materials and reaction conditions, which can lead to a significant increase in costs and a rise in prices. < Br >
    Second, the amount of demand. If in a certain field, many industry players or researchers have strong demand for this product, and the supply is in short supply, the price will also increase. However, if this product is not a widely used chemical, the demand may be limited, and the price should be relatively stable.
    Third, the quality is different. Produced by different manufacturers, due to differences in process and quality control, the quality is poor and the price is also different. High quality, the price is higher.
    In summary, although it is difficult to determine the market price of "4- (2,2-diethyl-1,3-naphthalene-heterocyclopentene-dioxide-4-yl) -1H-pyrrole-3-acetic acid", it is largely influenced by factors such as production, demand, and quality. To know the exact price, you can consult chemical reagent suppliers, chemical product trading platforms, etc., to obtain more accurate price information.
    What are the safety and toxicity of 4- (2,2-difluoro-1,3-benzodioxane-4-yl) -1H-pyrrole-3-formonitrile?
    4- (2,2-diethyl-1,3-naphthaleno-heterocyclopentene dioxide-4-yl) -1H-pyrrole-3-acetic acid is an organic compound. To know its safety and toxicity, it is necessary to explore it through multiple channels.
    First look at its chemical structure. This compound contains specific functional groups and structural units, and some structures may be related to known toxic groups. However, it is difficult to determine its toxicity based on the structure alone, and only the latent risk can be preliminarily inferred.
    Animal experiments were re-examined. Taking suitable animals as the object, different doses of this compound were administered by different routes (such as oral administration, injection, etc.) to observe the animal reaction. If high doses cause significant abnormalities in animals, such as weight loss, behavioral changes, organ damage, etc., it indicates high toxicity; if low doses also cause adverse effects for a long time, such as carcinogenesis, teratogenesis, etc., there is also a latent risk.
    Human studies are also critical. Although it is not possible to directly test toxicity in humans, it is possible to study the health status of exposed populations. If the prevalence of long-term exposure to this compound increases, or specific health problems occur, it can be supported by its toxicity.
    In addition, it is also helpful to refer to data on similar compounds. If structural analogs have been shown to be toxic, this compound may also have similar toxicity.
    After many studies and analyses, the safety and toxicity of 4- (2,2-diethyl-1,3-naphthalene-heterocyclopentene-4-yl) -1H-pyrrole-3-acetic acid can be accurately recognized, which provides a basis for its rational use and risk prevention and control.