As a leading (3R,5R)-tert-Butyl 7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of (3R, 5R) -tert-Butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylcarbamoyl) -1H-pyrrol-1-yl] -3, 5-dihydroxyheptanoate?
" (3R, 5R) -tert-Butyl" indicates a specific stereoconfiguration (R configuration) at specific positions (3 and 5 positions) of the molecule, and is connected with tert-butyl. " 7 - [2 - (4 - fluorophenyl) -5 - isopropyl - 3 - phenyl - 4 - (phenylcarbamoyl) -1H - pyrrol - 1 - yl] "This section reveals that position 7 is connected to a complex pyrrole ring derivative. The pyrrole ring has 4-fluorophenyl at position 2, isopropyl at position 5, phenyl at position 3, and benzoyl at position 4." 3,5 - dihydroxyheptanoate "indicates that the main chain is heptanoate, with one hydroxyl group at positions 3 and 5.
In summary, the chemical structure of this compound is based on heptanoate containing a specific stereoconfiguration as the main chain, complex pyrrole ring derivatives at the 7th position, and hydroxyl groups at the 3rd and 5th positions, respectively. This is a summary of the chemical structure inferred by the name.
(3R, 5R) -tert-Butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylcarbamoyl) -1H-pyrrol-1-yl] -3, What are the physical properties of 5-dihydroxyheptanoate?
The physical properties of (3R, 5R) -tert-butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylcarbamoyl) -1H-pyrrole-1-yl] -3,5-dihydroxyheptanoate are particularly important for its performance in various applications.
When it comes to appearance, it is usually white to off-white crystalline powder, which is intuitively observable. Its melting point is in a specific range, roughly within the [specific melting point range], which is a key indicator for identification and purity determination. The determination of melting point can be achieved by thermal analysis technology, and the accuracy is related to the purity and structural integrity of the substance. < Br >
Solubility is also an important property. In organic solvents, such as methanol, ethanol, dichloromethane, etc., it exhibits a certain solubility, which is conducive to its operation in synthesis, separation and preparation. In water, the solubility is relatively limited, and this difference is closely related to the polarity and structure of the molecule.
In terms of density, [specific density value] reflects the mass of a substance per unit volume, which is of great significance in storage, transportation and preparation process considerations. Its density affects material handling, packaging design and other aspects.
Stability is stable under conventional conditions. However, in the case of high temperature, high humidity or strong light environment, degradation or chemical changes may occur. If at high temperature, the vibration of intramolecular chemical bonds intensifies, which may cause the pyrrole ring or ester bond to break, affecting the quality and activity of the substance.
In summary, (3R, 5R) -tert-butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylcarbamoyl) -1H-pyrrole-1-yl] -3,5-dihydroxyheptanoate The physical properties of the substance cover appearance, melting point, solubility, density and stability, etc. The properties are related to each other and jointly determine the application and treatment methods of the substance in scientific research, production and other fields.
(3R, 5R) -tert-Butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylcarbamoyl) -1H-pyrrol-1-yl] -3, What are the synthesis methods of 5-dihydroxyheptanoate?
The synthesis of (3R, 5R) -tert-butyl 7- [2 - (4 - fluorophenyl) - 5 - isopropyl - 3 - phenyl - 4 - (phenylcarbamoyl) - 1H - pyrrole - 1 - yl] - 3,5 - dihydroxyheptanoate is the key to organic synthesis chemistry. The synthesis of this compound is very complex and needs to follow specific steps and strategies.
In the initial stage, the pyrrole ring structure of the core can be constructed. Using suitable fluorobenzene derivatives, isopropyl substituents, and phenyl compounds as raw materials, pyrrole rings with specific substituents are formed through a series of reactions such as condensation and cyclization. This process requires careful regulation of reaction conditions, such as temperature, pH, catalyst type and dosage, etc., to ensure that the reaction progresses in the expected direction and a pyrrole ring intermediate with high yield and purity is obtained.
Furthermore, for the construction of heptanoate moiety, it can be obtained by selecting suitable starting materials and gradually converting functional groups. For example, starting with a specific carboxylic acid derivative, tert-butyl groups are introduced through esterification and then hydroxylated to precisely form 3,5-dihydroxyl structures.
Finally, the constructed pyrrole ring structure is connected to the heptanoate fragment. This step may be achieved by means of a coupling reaction. Efficient coupling reagents and catalysts are selected to optimize the reaction conditions, so that the two can be effectively combined to form the target product (3R, 5R) -tert-butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylaminoformyl) -1H-pyrrole-1-yl] -3,5-dihydroxyheptanoate. However, the road to synthesis is fraught with difficulties, and each step of the reaction needs to be carefully controlled. The product also needs to be strictly separated and purified in order to obtain a high-quality final product, which lays a solid foundation for subsequent research and application.
(3R, 5R) -tert-Butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylcarbamoyl) -1H-pyrrol-1-yl] -3, 5-dihydroxyheptanoate in what fields?
(3R, 5R) -tert-butyl 7- [2 - (4 - fluorophenyl) - 5 - isopropyl - 3 - phenyl - 4 - (phenylcarbamoyl) - 1H - pyrrole - 1 - yl] - 3,5 - dihydroxyheptanoate This substance is used in the field of medicine and may have the effect of lowering lipids. Guanfstatin drugs have the ability to regulate blood lipids, and the structure of this compound is similar to it, or it can affect the key link of cholesterol synthesis, such as inhibiting hydroxymethylglutaryl-CoA reductase, thereby reducing the generation of endogenous cholesterol, for the prevention and treatment of hyperlipidemia.
In the field of organic synthesis, its complex structure can provide challenges and opportunities for synthetic chemists. Synthesis of this compound requires delicate design of reaction routes, selection of appropriate reaction conditions and reagents to construct unique carbon frameworks and functional groups. This process can promote the development of organic synthesis methodologies and accumulate experience for the creation of new complex structure compounds.
In the context of drug development, this compound can be used as a precursor, and through structural modification and optimization, drugs with better activity and higher safety may be obtained. The study of its structure-activity relationship can understand the relationship between structural changes and biological activity, and guide the direction of new drug design to promote the innovation of cardiovascular disease treatment drugs.
(3R, 5R) -tert-Butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylcarbamoyl) -1H-pyrrol-1-yl] -3, What is the market outlook for 5-dihydroxyheptanoate?
Today there is a product called% 283R% 2C5R% 29 - tert - Butyl 7 -% 5B2 -% 284 - fluorophenyl% 29 - 5 - isopropyl - 3 - phenyl - 4 - %28phenylcarbamoyl%29 - 1H - pyrrol - 1 - yl% 5D - 3% 2C5 - dihydroxyheptanoate. To see its market prospects, it needs to be explored more.
This product may be used in pharmaceutical research and development, but the rules of medicine are strict. New drugs have to go through a long road, from laboratory research to human trials, and then get regulatory approval, and it is difficult step by step. If it has significant advantages over existing drugs in the treatment of specific diseases, such as better curative effect and fewer side effects, it is expected to be favored by the market. However, the competition for new drugs is fierce, and many pharmaceutical companies are following this path. It is not easy for new material desires to stand out.
If you are involved in the chemical industry, chemical production focuses on safety and environmental protection. The production process of this product needs to consider the difficulty of obtaining raw materials, the cost, and the production process may affect its quality and output. If it can conform to the green and efficient development trend of the chemical industry and find stable demand, it may be able to occupy a place in the chemical market.
Furthermore, marketing activities are also critical. It is necessary to accurately locate the target customers, whether it is the procurement of pharmaceutical companies or the needs of chemical companies, to let them know the characteristics and advantages of this product. However, the promotion method is costly and laborious, and the market is changing rapidly, and the promotion strategy must also change in a timely manner.
Overall,% 283R% 2C5R% 29 - tert - Butyl 7 -% 5B2 -% 284 - fluorophenyl% 29 - 5 - isopropyl - 3 - phenyl - 4 - %28phenylcarbamoyl%29 - 1H - pyrrol - 1 - yl% 5D - 3% 2C5 - dihydroxyheptanoate market prospects, opportunities and challenges coexist, need to be properly weighed in R & D, production and promotion in order to seek development.
