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3-Amino-2-ethoxycarbonylpyrrole chemical structure of hydrochloride
3-Amino-2-ethoxycarbonyl pyrrole hydrochloride, this is an organic compound. In its structure, the pyrrole ring is a key part, and the pyrrole ring is a five-membered heterocyclic ring composed of four carbon atoms and one nitrogen atom, which is aromatic. At position 2 of the pyrrole ring, there is an ethoxycarbonyl group, which is formed by connecting the ethyl group to the carbonyl group and the oxygen atom, that is, -COOCH -2 CH. The presence of the carbonyl group makes it chemically active and can participate in many reactions. At position 3, there is an amino group, that is, -NH -2. The amino group also has active chemical properties and can undergo various reactions such as nucleophilic substitution. Due to the formation of hydrochloride, it means that the amino group binds to the hydrogen ion in hydrochloric acid and exists in the form of -NH < unk > < unk > Cl, which enhances the physical properties of the compound in specific solvents. The structural characteristics of this compound determine that it can be used as a key intermediate in the field of organic synthesis and participates in the construction of various complex organic compounds.
What are the main uses of 3-Amino-2-ethoxycarbonylpyrrole hydrochloride?
3-Amino-2-ethoxycarbonyl pyrrole hydrochloride has a wide range of uses and is often a key synthetic building block in the field of medicinal chemistry. Due to its unique chemical structure, it can participate in the construction of many drug molecules and help develop new therapeutic drugs. Taking the synthesis of an antidepressant as an example, this compound is used as a starting material. After a series of chemical reactions, it ingeniously constructs the core skeleton of the drug, laying the foundation for the pharmacological activity of the drug.
In the field of materials science, it also has important uses. Or it can be used to prepare functional organic materials, which give the material specific optoelectronic properties by virtue of their structural properties. For example, after specific treatment, the material can respond to specific wavelengths of light, showing potential applications in optoelectronic devices such as Light Emitting Diodes and light sensors.
In organic synthetic chemistry, it is an important intermediate. Pyrrole derivatives with rich structures can be derived through various reactions, such as condensation reactions with aldose, ketone and other compounds, providing a powerful tool for organic synthesis chemists to explore the structure and properties of novel compounds. In short, 3-amino-2-ethoxycarbonyl pyrrole hydrochloride plays an indispensable role in many scientific fields and plays a significant role in promoting the development of related fields.
What are the synthetic methods of 3-Amino-2-ethoxycarbonylpyrrole hydrochloride?
The synthesis of 3-amino-2-ethoxycarbonyl pyrrole hydrochloride is an important topic in the field of organic synthesis. In the past, many sages have worked hard on this and have obtained several feasible methods.
First, the compound containing the pyrrole ring is used as the starting material. First, the specific pyrrole derivative is esterified with the reagent containing the ethoxycarbonyl group to construct the ethoxycarbonyl based on the second position of the pyrrole ring. In this process, the reaction conditions, such as temperature and catalyst, need to be carefully selected. Usually, at mild temperatures, with a suitable acid or base as the catalyst, the reaction can proceed smoothly. < Br >
After the ethoxycarbonyl is introduced, the amination reaction is carried out. In this step, an ammonia source, such as ammonia gas or an amine compound, is often used to interact with the above-mentioned products under specific conditions to introduce the amino group at the third position of the pyrrole ring. However, this reaction may face the challenge of regioselectivity, so the reaction conditions need to be precisely regulated to ensure that the amino group can be accurately introduced into the target position.
Another way is to start from a simple starting material and gradually construct the target molecule through a multi-step reaction. First, the basic skeleton of the pyrrole ring is constructed by a suitable organic synthesis method, and then the ethoxycarbonyl group and the amino group are introduced in sequence. For example, small molecules with suitable substituents can be cyclized to form pyrrole rings, and then the desired functional groups can be introduced in sequence. In this process, each step of the reaction requires strict control of the reaction conditions to ensure the yield and selectivity of the reaction.
When synthesizing 3-amino-2-ethoxycarbonyl pyrrole hydrochloride, a subsequent salt-forming reaction is required. With hydrochloric acid interacting with it, the target hydrochloride product can be obtained. This salt-forming reaction is relatively simple. Only by controlling the amount of hydrochloric acid and reaction conditions can a pure 3-amino-2-ethoxycarbonyl pyrrole hydrochloride be obtained. In short, the synthesis of this compound requires comprehensive consideration of the conditions and selectivity of each step of the reaction in order to achieve efficient and high-quality synthesis.
3-Amino-2-ethoxycarbonylpyrrole the physical and chemical properties of hydrochloride
3-Amino-2-ethoxycarbonyl pyrrole hydrochloride, its physical and chemical properties are quite important. Looking at its properties, it is mostly white to light yellow crystalline powder under normal conditions, which is a significant feature in appearance.
When it comes to solubility, it has a certain solubility in water, which is caused by the interaction between polar groups contained in the molecular structure and water molecules. It also has good solubility in polar organic solvents such as methanol and ethanol, but it is not good in non-polar organic solvents such as n-hexane.
The measurement of the melting point is about a certain temperature range, which can be used as an important indicator to identify the substance. Because the melting point of a substance is affected by many factors such as intermolecular forces and lattice structure, the melting point of this compound is a specific value, which reflects the stability and order of its molecular structure.
In terms of acidity and alkalinity, because it is a hydrochloride salt, hydrogen ions can be ionized in aqueous solution, showing acidity. This acidic property plays a key role in many chemical reactions and applications, and can participate in reactions such as acid-base neutralization.
In terms of stability, it is relatively stable in a normal temperature, dry and dark environment. However, in case of high temperature, high humidity or strong light irradiation, decomposition reactions may occur, causing changes in its structure and properties. This stability feature requires corresponding storage and transportation conditions. The physicochemical properties of 3-amino-2-ethoxycarbonyl pyrrole hydrochloride, such as appearance, solubility, melting point, acidity and stability, are of great significance for its application in chemical synthesis, drug development and other fields. Researchers need to consider in detail to make good use of its characteristics.
3-Amino-2-ethoxycarbonylpyrrole hydrochloride in storage and transportation
3-Amino-2-ethoxycarbonyl pyrrole hydrochloride, when storing and transporting, many matters need to be paid attention to.
Its properties may have potential effects on the environment and human body, so when storing, it should be placed in a cool, dry and well-ventilated place. These conditions can avoid the risk of moisture and heat-induced deterioration. If it is damp, or triggers a chemical reaction, causing the composition to change; excessive heating, or decomposition and volatilization, damaging its quality.
Furthermore, it needs to be placed separately from oxidants, acids, bases and other substances. Due to its chemical properties, contact with the above substances is prone to violent reactions or dangerous. In case of strong oxidants, or risk of combustion or explosion.
Storage containers also need to be careful, and those that are resistant to corrosion and well sealed should be selected. If the glass container has poor texture or is corroded by it; if the seal is poor, it is easy to react with air components, and the volatile gas may also be harmful.
When transporting, the packaging must be firm. Make sure that the container is not damaged and leaked during bumps and collisions. The transportation vehicle should also be clean and free of other chemical substances to avoid mixed reactions. And the transportation personnel should have professional knowledge and be familiar with the characteristics of this material and emergency response methods. In the event of leakage, etc., they can quickly take correct measures to avoid the expansion of hazards. Therefore, Fangbao 3-amino-2-ethoxycarbonyl pyrrole hydrochloride is safe during storage and transportation.