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What is the chemical structure of 3,6-diphenyl-2,5-dihydropyrrole [3,4-c] pyrrole-1,4-dione?
This is an extremely complex organic compound with a long name and contains many specific functional groups and structural information. To clarify its chemical structure, it is necessary to analyze it step by step according to the rules of organic chemistry.
"3,6-dibenzyl-2,5-dihydropyrrole [3,4-c] pyrrole-1,4-dione", "pyrrole [3,4-c] pyrrole" determines the basic parent nucleus structure, which is formed by the fusing of two pyrrole rings in a specific way. At the 3rd and 6th positions, there is a benzyl group connected to each other, that is, the -CH ² -phenyl structure; the 2nd and 5th positions are in a dihydrogen state, which means that the carbon atoms at these two places are connected to the hydrogen atom and are not completely unsaturated; the 1st and 4th positions each have a carbonyl group (C = O), forming a diketone structure.
Describe its structure in words, just like two pyrrole rings fused to each other, like a conjoined pavilion. Positions 3 and 6 resemble the branches protruding from the side of a pavilion, each connected with a specific group of benzyl; positions 2 and 5 resemble the part where the pavilion is not fully built, leaving hydrogen atoms; positions 1 and 4 resemble the specific decoration of a pavilion, each with a carbonyl modification. In this way, the chemical structure of this compound can be analyzed in this way, and its approximate appearance can be constructed in mind.
What are the physical properties of 3,6-diphenyl-2,5-dihydropyrrole [3,4-c] pyrrole-1,4-dione?
3% 2C6-dibenzyl-2% 2C5-dihydropyrrolido [3% 2C4-c] pyrrole-1% 2C4-dione, this is an organic compound. Its physical properties are important for its application in many fields.
The appearance of this substance is often specific, or it is a crystalline solid with a specific color, perhaps white to light yellow. This color is related to the crystalline morphology, and is related to the atomic arrangement and electron cloud distribution in the molecular structure. The structure of benzyl, pyrrole ring and dione in the molecule affects the absorption and scattering of light, resulting in its corresponding appearance.
Melting point is also a key physical property. Due to the intermolecular force, when a certain temperature is reached, the molecule obtains enough energy to overcome the force, the lattice structure disintegrates, and the solid state converts to a liquid state. The melting point temperature depends on the intermolecular force, including hydrogen bonds, van der Waals forces, etc.
Solubility is equally important. In organic solvents such as dichloromethane and chloroform, due to the principle of similar miscibility, molecules and solvent molecules can form a favorable interaction, so they are soluble. In water, due to the large difference between molecular polarity and water, it is difficult to form an effective interaction and poor solubility.
In addition, its density is also one of the characteristics, reflecting the mass per unit volume, which is related to the degree of close accumulation of molecules. The physical properties of this compound are of great significance in the fields of organic synthesis, medicinal chemistry, etc., which help separation and purification during synthesis. Pharmacokinetic properties such as absorption and distribution are involved in drug development.
What are the main uses of 3,6-diphenyl-2,5-dihydropyrrole [3,4-c] pyrrole-1,4-dione?
3,6-Dibenzyl-2,5-dihydropyrrolido [3,4-c] pyrrole-1,4-dione, this is an organic compound. Its main uses are quite extensive, and it is often used as a key intermediate in the field of organic synthesis.
Because of its special structure, it contains the core structure of pyrrolidone, and the benzyl group is attached to a specific position, giving the compound unique reactivity and spatial structure. With this property, chemists can modify and transform it through various chemical reactions to synthesize a series of organic molecules with complex structures and specific functions, such as new drugs, functional materials, etc.
In the field of drug development, this compound may exhibit potential biological activity due to the compatibility of its structure with the biological activity check point. Researchers can search for lead compounds with better pharmacological activity and lower toxicity by optimizing and modifying its structure, laying the foundation for new drug creation.
In the field of materials science, due to the electronic effect of intra-molecular conjugate structure and benzyl group, the compound may exhibit unique optical and electrical properties. It can be used to prepare organic optoelectronic materials, such as organic Light Emitting Diode (OLED), organic solar cells, etc., providing the possibility for the development of high-efficiency and low-cost new materials. < Br >
With its unique structure and properties, this compound has important application value and research significance in many fields such as organic synthesis, drug development, and materials science.
What are the synthesis methods of 3,6-diphenyl-2,5-dihydropyrrole [3,4-c] pyrrole-1,4-dione?
To prepare 3,6-dibenzyl-2,5-dihydropyrrolido [3,4-c] pyrrole-1,4-dione, there are many methods. Ancient chemists often use exquisite methods to transform ordinary things as magic.
One, or take a derivative of pyrrole, and use benzyl halide with it, with the help of alkali, to carry out nucleophilic substitution. Alkali, such as potassium carbonate, sodium hydroxide, etc., can provide a suitable environment for the reaction. During the reaction, the control of temperature and time is the key. If the temperature is too high, it may cause side reactions; if it is too low, the reaction will be slow. Here, when the appropriate temperature is found, the reaction is slow, and the benzyl group is successfully attached to the pyrrole, and then the subsequent steps such as oxidation are carried out to form the structure of diketones.
Second, there are also those prepared by cyclization reaction. First, a chain compound with suitable functional groups is prepared, and it is ingeniously designed to undergo intramolecular cyclization under specific conditions. For example, a chain containing an amino group and a carbonyl group is catalyzed by an acid or a base. Here, the choice of catalyst and the proportion of reactants need to be carefully considered. Improper ratio, the effect of cyclization is not good; the catalyst is not suitable, and the reaction is difficult. After cyclization, the benzyl group is modified to obtain the target.
Third, the method of transition metal catalysis can still be used. Select suitable transition metals, such as palladium, copper, etc., use them as the catalytic core, and cooperate with specific ligands to cause coupling reactions between the reactants. In this process, the combination of metals and ligands and the properties of the reaction solvent have a great impact on the reaction. Selecting the right solvent can increase the solubility of the reactants and promote the reaction; suitable ligands can improve the activity and selectivity of metal catalysis. After a series of steps such as coupling and cyclization, 3,6-dibenzyl-2,5-dihydropyrrole [3,4-c] pyrrole-1,4-dione is finally obtained.
All kinds of production methods have advantages and disadvantages. Fang family needs to weigh and choose according to their own raw materials and conditions in order to obtain this compound in the best way.
What are the precautions for using 3,6-diphenyl-2,5-dihydropyrrole [3,4-c] pyrrole-1,4-dione?
3% 2C6-dibenzyl-2% 2C5-dihydropyrrole [3% 2C4-c] pyrrole-1% 2C4-diketone During use, there are many key matters to be paid attention to.
First, safety protection must be in place. This substance may have certain toxicity and irritation. During operation, it should be fully armed and wear protective gloves, protective glasses and masks to avoid direct contact with the skin and eyes, and prevent inhalation of its dust or volatile gases, otherwise it is very likely to cause damage to the body.
Second, accurately control the reaction conditions. Temperature, pH, reaction time and other factors have a profound impact on the reaction process and product purity. For example, if the temperature is too high, side reactions may occur frequently, and if it is too low, the reaction rate will be slowed down. Therefore, the reaction conditions must be precisely adjusted according to the specific reaction requirements, with the help of thermometers, pH test strips and other tools.
Third, the storage environment should be suitable. It should be stored in a cool, dry and well-ventilated place, away from fire sources and oxidants. Because the substance may be flammable or react violently with oxidants, improper storage can easily lead to safety accidents.
Fourth, strictly implement the operating specifications. Whether it is weighing, dissolving, or mixing operations, it must be carried out in accordance with established standard procedures. For example, when weighing, use an accurate balance to ensure that the dosage is accurate; when dissolving, use a suitable solvent and stir well to promote dissolution.
Fifth, do a good job of waste disposal. After use, the remaining substances and the generated waste must not be discarded at will. It needs to be sorted, collected and properly disposed of in accordance with relevant regulations to prevent pollution to the environment.