2-phenyl-4H-furo[3,2-b]pyrrole-5-carboxylic acid

This is the chemical structure analysis of 2-phenyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid. This compound contains the core structure of furanopyrrole, which is formed by fusing a furan ring with a pyrrole ring. This fused structure is common in many biologically active natural products and synthetic drugs. "4H" indicates that in this furanopyrrole ring system, the hydrogen atom at the 4 position is one part of the ring structure. The 2-position connecting phenyl group, the phenyl group is a group formed by removing a hydrogen atom from the phenyl ring. The phenyl ring is highly conjugated and often affects the physical, chemical and biological activities of the compound. 5-Position linked carboxyl group, the carboxyl group is formed by linking the carbonyl group to the hydroxyl group, which gives the compound acidic properties and can participate in a variety of chemical reactions, such as salt formation reactions, esterification reactions, etc. The interaction of various parts in this chemical structure determines the overall properties and reactivity of the compound. It is crucial to understand its properties and potential applications in pharmaceutical chemistry, organic synthetic chemistry and other fields.

2-Phenyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid is an organic compound. It has various important physical properties and is related to many applications in chemistry and related fields.
Looking at its properties, it is mostly in a solid state at room temperature and pressure. The color state of this compound may vary depending on the purity and crystal form, but it is usually a white to off-white powder with a fine texture. The size of its particle size will also vary depending on the preparation process, but it is generally within a considerable range, and this characteristic is very critical when studying and using powders.
When it comes to melting point, this compound has a specific melting point value, which is an important indicator for identification and purity judgment. Its melting point is often in a certain temperature range, due to factors such as impurities, or the melting point is slightly offset. Accurate determination of melting point requires precise instruments and standard operating procedures in order to obtain accurate data.
Solubility is also an important physical property. In common organic solvents, its solubility varies. In some organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., it has a certain solubility and can form a uniform solution. This characteristic provides a basis for the selection of reaction solvents in organic synthesis reactions, and is related to the smooth progress of the reaction and the separation and purification of the product. In water, its solubility is negligible, which is related to the presence of hydrophobic groups in the molecular structure.
Density is also a physical property that cannot be ignored. Although its density data is specific, it is of great significance in considering the relationship between mass and volume of substances, as well as in some studies involving hydrodynamics or mixed systems. Knowing its density can help to rationally design experimental equipment and processes to ensure the accuracy and safety of related operations.
In summary, the physical properties of 2-phenyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid, such as color state, melting point, solubility and density, are the key to in-depth understanding of this compound, providing an important foundation for research and application in various fields such as organic chemistry, medicinal chemistry and materials science.

The common synthesis methods of 2-phenyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid can be roughly explored from the following ways.
First, it can be obtained by the cyclization reaction of furan and pyrrole derivatives. First, find a suitable furan derivative with an active group that can be cyclized with pyrrole derivatives in its side chain. For example, using a halogenated alkyl furan derivative and an active amino-containing pyrrole derivative as starting materials, under the action of a suitable base and catalyst, the amino group is nucleophilized to the halogenated alkyl group, and then the intracolecular cyclization is performed to construct the parent nuclear structure of furanopyrrole. Under appropriate conditions, a carboxyl group is introduced into the 5-position of the parent nucleus, which can be reacted with carboxyl-containing precursors, such as the reaction of halogenated compounds with cyanide to form a nitrile group, which is then converted into a carboxyl group by hydrolysis.
Second, the furan-pyrrole structure is gradually established by starting with the benzene ring. Functional groups that can be related to the construction of furan and pyrrole are introduced on the benzene ring first, such as halogen atoms or alkenyl groups. With halogenated benzene as the group, through a metal-catalyzed coupling reaction, it is first connected to the furan derivative fragment, and then connected to the pyrrole fragment and cyclized through a series of reactions, such as nucleophilic addition and elimination. The subsequent steps are also as above to complete the introduction of the 5-position carbox In this process, the choice of metal catalysts is crucial. Metal catalysts such as palladium and copper can often promote key coupling and cyclization reactions at different stages.
Third, there are also synthesizers achieved by multi-step series reactions. The starting material is reacted continuously in multiple steps without the separation of intermediates, and the target molecule is directly constructed. This requires precise control of the reaction conditions of each step, so that each reaction occurs in sequence and proceeds efficiently. For example, starting compounds containing multiple active check points first initiate the construction of furan rings, and then the formation of pyrrole rings and subsequent carboxylation modification reactions are triggered by changes in conditions in the system. Although this approach is complicated, it can improve the synthesis efficiency and reduce the loss of intermediate products.

2-Phenyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid, this compound has extraordinary uses in many fields such as medicine and materials science.
In the field of medicine, it may be used as a potential drug lead compound. Because the compound has a unique chemical structure, it may interact with specific targets in organisms. If modified by research, it may act precisely on certain disease-related proteins to achieve the effect of treating diseases. Modern medical research often explores such compounds with special structures, hoping to find innovative drugs, 2-phenyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid or in the development of anti-cancer, anti-inflammatory and other drugs.
In the field of materials science, it also has potential application value. Due to its structural properties, it may be used to prepare special functional materials. For example, it may be able to participate in the synthesis of materials with unique optical and electrical properties. In the field of organic optoelectronic materials, such compounds can be rationally designed and assembled, and may improve the photoelectric conversion efficiency of materials. They are used in organic Light Emitting Diodes, solar cells and other devices, contributing to the development of energy and display technologies.
In addition, in the field of chemical synthesis, 2-phenyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid can be used as a key intermediate. Chemists can use its unique structure to carry out various chemical reactions, construct more complex and specific functional compounds, expand the chemical boundaries of organic synthesis, and provide rich possibilities for the creation of new compounds.

2-Phenyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid is a unique organic compound. Looking at its market prospects, it can be said to have great potential, but it also faces several challenges.
From the perspective of the pharmaceutical field, many studies have focused on compounds containing furano-pyrrole structures, which often exhibit diverse biological activities, such as anti-cancer, anti-inflammatory and antibacterial properties. 2-Phenyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid may be structurally modified to develop new drugs. Nowadays, there is a great demand for the treatment of major diseases such as cancer. If this compound can make achievements in the development of anti-cancer drugs, its market space will be extremely broad. However, the road to drug development is long, and it requires rigorous clinical trials, which requires huge investment of manpower, material resources and time. This is a major challenge.
In the field of materials science, organic compounds are often used to synthesize functional materials. 2-phenyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid or because of its unique molecular structure, gives materials special photoelectric properties. For example, it can be used to prepare organic Light Emitting Diode (OLED) materials. With the vigorous development of display technology, the market demand for OLED continues to grow. If this compound can be applied here, the prospect is promising. However, material applications need to solve problems such as stability and cost. The stability of materials in different environments is crucial, and cost reduction can achieve large-scale production and application.
Furthermore, the research field of scientific research is very enthusiastic about the research of novel organic compounds. 2-Phenyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid may become a hot object of scientific research, providing many opportunities for academic research, and then promoting the theoretical development of related fields. However, the transformation of scientific research results is not easy, and a good industry-university-research cooperation platform needs to be established in order to effectively transform scientific research results into actual productivity.
Overall, the market for 2-phenyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid has a bright future. However, in terms of drug research and development, material application and transformation of scientific research results, many difficulties still need to be overcome. If it can be properly dealt with, it will be able to occupy a place in the market.