2 Methyl 4h Furo 3 2 B Pyrrole 5 Carboxylic Acid Ethyl Ester
pyridine pyrrole pyrazine piperidine piperazine

2-Methyl-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester

    Specifications

    HS Code

    914187

    Name 2-Methyl-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester
    Chemical Formula C10H11NO3
    Molar Mass 193.2 g/mol
    Appearance Solid (usually)
    Melting Point Data needed
    Boiling Point Data needed
    Solubility In Water Low solubility (usually)
    Solubility In Organic Solvents Soluble in some organic solvents
    Density Data needed
    Flash Point Data needed
    Pka Data needed

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    What are the chemical properties of 2-Methyl-4H-furo [3,2-b] pyrrole-5-carboxylic acid ethyl ester
    2-Methyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid ethyl ester, this is an organic compound. Looking at its structure, furan and pyrrole are combined to form a unique heterocyclic ring, and the ring is connected with methyl, ethyl ester and carboxyl groups.
    In terms of physical properties, its properties are mostly solid or oily liquids, which vary depending on the specific preparation and purity. Melting point, boiling point and other melting point parameters are subject to intermolecular forces, such as van der Waals force, hydrogen bonds, etc. Its solubility is closely related to molecular polarity. This compound has both polar groups and non-polar hydrocarbon moieties, so it has a certain solubility in organic solvents such as dichloromethane and ethanol, but poor solubility in water.
    When it comes to chemical properties, ethyl ester groups have ester properties and can undergo hydrolysis reactions catalyzed by acids or bases. When exposed to acid, it is protonated, and water molecules attack carbonyl carbons and gradually hydrolyze into carboxylic acids and ethanol; when exposed to alkali, hydroxide ions attack carbonyl carbons to form carboxylic salts and ethanol, and hydrolysis is more thorough.
    Furthermore, pyrrole rings have electron-rich properties and are prone to electrophilic substitution reactions. Because of the conjugation of lone pairs of nitrogen atoms, the electron cloud density on the ring increases. Common electrophilic reagents such as halogenated reagents can undergo halogenation reactions at the appropriate position of the pyrrole ring; acylation reactions can occur with acylating reagents.
    In addition, the acidic hydrogen atoms contained in the compound, such as carboxyl hydrogen, can be deprotonated under the action of appropriate bases to generate corresponding salts, which affects its existence form and reactivity in solution. Its unique structure imparts a variety of chemical reactivity and can be used as a key intermediate in the field of organic synthesis to construct more complex compounds.
    What are the synthesis methods of 2-Methyl-4H-furo [3,2-b] pyrrole-5-carboxylic acid ethyl ester
    The method of preparing 2-methyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid ethyl ester is the gist of organic synthesis. One method can be started with furan and pyrrole derivatives with corresponding substituents. First, take a suitable furan compound and make it condensate with pyrrole substances under specific conditions. This condensation reaction requires the selection of a suitable catalyst, such as some Lewis acids, to promote the combination of the two to construct the basic structure of furanopyrrole.
    When the reaction is carried out, the choice of temperature and solvent is very critical. Aprotic solvents, such as dichloromethane, N, N-dimethylformamide, etc. are often used to create a reaction environment. The temperature is finely regulated according to the activity of the reactants and the reaction process, or varies from room temperature to moderate heating. After the initial formation of the
    structure, a carboxyl ethyl ester group is to be introduced. It can be used by suitable acylating agents, such as halogenated ethyl acetate, in the presence of bases, to interact with the previous products. The strength and dosage of bases need to be carefully considered to avoid overreaction or side reactions. Common bases include potassium carbonate, potassium tert-butanol, etc. < Br >
    After this series of reactions, 2-methyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid ethyl ester can be obtained. However, after the reaction, the product or impurities need to be purified by column chromatography, recrystallization and other means to obtain a high-purity target product for subsequent research or application.
    In which fields is 2-Methyl-4H-furo [3,2-b] pyrrole-5-carboxylic acid ethyl ester used?
    2-Methyl-4H-furano [3,2-b] pyrrole-5-carboxylic acid ethyl ester, this is an organic compound that has applications in various fields.
    In the field of pharmaceutical research and development, organic compounds are often the key starting materials for the creation of new drugs. This compound has a unique chemical structure or gives it specific biological activity. Through structural modification and pharmacological research, lead compounds with therapeutic effects can be found, and then new drugs for specific diseases can be developed. For example, it may act on specific biological targets, affect cellular physiological processes, and bring opportunities to overcome difficult diseases. < Br >
    In the field of materials science, organic compounds can be specially treated to make materials with special properties. Ethyl 2-methyl-4H-furano [3,2-b] pyrrole-5-carboxylate or due to its own structural characteristics, it has optical and electrical properties. After rational design and processing, it may be applied to optoelectronic devices, such as organic Light Emitting Diodes, solar cells, etc., to improve device performance and efficiency.
    Furthermore, in the field of fine chemicals, it can be used as an intermediate for the synthesis of fine chemicals. Fine chemicals are widely used in coatings, fragrances, additives and other products. Starting from this compound, through a series of chemical reactions, fine chemicals with specific functions and uses can be synthesized to meet different industrial and living needs, and to improve product quality and added value.
    2-Methyl-4H-furo [3,2-b] pyrrole-5-carboxylic acid ethyl ester
    2-Methyl-4H-furano [3,2-b] pyrrole-5-carboxylate ethyl ester, this product has considerable market prospects in the current market. It has unique value in the field of organic synthesis. Guanfu Pharmaceutical's research and development, the synthesis path of many innovative drugs, often rely on this compound as a key intermediate. Due to its special chemical structure, it can give unique activity and function to drug molecules, and help the creation of new drugs. It may make significant contributions to the treatment of difficult diseases. It is in the pharmaceutical industry that demand is expected to grow.
    In the field of materials science, it is also emerging. It can be integrated into the structure of new materials through specific chemical reactions, so that the materials have special photoelectric or mechanical properties, opening up new paths for the development of electronic devices, optical materials, etc. And with the advance of science and technology, the exploration and application of such compounds with special structures are in the ascendant.
    However, although the market prospect is beautiful, there are also challenges. First, the optimization of the synthesis process is crucial. To expand the production scale and meet the growing demand, the synthesis process must be more efficient, environmentally friendly and cost-controllable. Second, the competitive situation should not be underestimated. As its potential value is recognized, the competition in the industry may become more intense, and enterprises need to find a balance between technological innovation, quality control and cost advantage.
    Overall, the market prospect of 2-methyl-4H-furano [3,2-b] pyrrole-5-carboxylate ethyl ester is promising, but practitioners need to carefully plan between opportunities and challenges in order to enjoy its benefits and promote the vigorous development of related industries.
    What are the precautions in the preparation of 2-Methyl-4H-furo [3,2-b] pyrrole-5-carboxylic acid ethyl ester
    In the process of preparing 2-methyl-4H-furano [3,2-b] pyrrole-5-carboxylate, many things need to be paid attention to. The quality and purity of the first raw material are related to whether the reaction can be smooth and the purity of the product. If there are too many impurities in the raw material, it may cause side reactions and reduce the yield of the product.
    Furthermore, precise control of the reaction conditions is the key. The temperature can affect the reaction rate and direction, and it is not a good strategy to go too high or too low. For example, if the temperature is too high, the reaction may be too violent, causing unnecessary side reactions; if the temperature is too low, the reaction will be slow and time-consuming. The reaction time also needs to be strictly controlled. If it is not enough, the reaction will not be fully functional, and if it is too long, it will cause the product to decompose.
    The choice of solvent should not be underestimated. Different solvents affect the solubility and reactivity of the reactants. The appropriate solvent should be selected according to the reaction mechanism and the characteristics of the reactants to create a good reaction environment.
    During the reaction process, the intensity and uniformity of stirring are also related to the reaction effect. Full stirring can promote full contact of the reactants, make the reaction more uniform and improve the reaction efficiency.
    In addition, the post-treatment steps also need to be treated with caution. The separation and purification of the product will affect the purity and quality of the final product. Commonly used separation methods such as extraction, distillation, recrystallization, etc., each have their own scope of application and operation points, and need to be reasonably selected according to the characteristics of the product.
    The entire preparation process is like a finely crafted skill, and every link needs to be treated carefully. A slight error may affect the quality and yield of the product. Only through thorough consideration and careful operation can the ideal preparation effect be achieved.