2-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID ETHYL ESTER

2-Methyl-1H-pyrrole-3-carboxylic acid ethyl ester, this is an organic compound, which has specific chemical properties.
Its physical properties, at room temperature or in a liquid state, have a certain volatility, with a special smell. The melting point and boiling point are determined by the atomic connection and interaction in the molecular structure. It contains an ester group and a pyrrole ring, which makes the intermolecular force characteristic, and the melting boiling point is in the corresponding range.
In terms of chemical properties, the ester group is active. Under acidic conditions, hydrolysis can occur to form 2-methyl-1H-pyrrole-3-carboxylic acid and ethanol; under alkaline conditions, hydrolysis is easier to proceed to form carboxylate and ethanol, which can neutralize the generated acid due to the alkali, so that the reaction equilibrium shifts to the right.
Because of its pyrrole ring, aromatic, electrophilic substitution reaction can occur, the electron cloud density distribution on the pyrrole ring is uneven, and specific positions are more susceptible to electrophilic attack, such as halogenation, nitrification and other substitution reactions. The substitution position is affected by the substituent group such as methyl on the ring. Methyl is the power supply sub-group, which affects the electron cloud distribution and determines the electrophilic substitution reaction check point.
At the same time, the compound may participate in reduction reactions, such as ester groups can be reduced to alcohols under specific conditions, and can also undergo condensation reactions with compounds containing active hydrogen. It is widely used in the field of organic synthesis and can be used as an intermediate to prepare more complex organic compounds for use in drug synthesis, material chemistry, and many other fields.

2-Methyl-1H-pyrrole-3-carboxylic acid ethyl ester, which has a wide range of uses. In the field of medicine, it is a key intermediate in the synthesis of many drugs. The structure of Geinpyrrole plays an important role in many drug molecules. With 2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester, different functional groups can be added through various chemical reactions, and then drug molecules with specific pharmacological activities can be constructed. For example, in the preparation of some antibacterial drugs and anti-tumor drugs, it is often used as a starting material and chemically modified to obtain new drugs with good curative effect.
In the field of materials science, it also has good performance. It can be used to synthesize polymer materials with special properties. Due to its pyrrole ring, the material is endowed with unique electronic structure and physicochemical properties. After specific polymerization reactions, polymer materials with good electrical conductivity, optical activity or thermal stability can be prepared, which are very useful in electronic devices, optical sensors, etc. For example, in the synthesis of organic Light Emitting Diode (OLED) materials, the introduction of this compound structure can optimize the luminescent properties of the material, improve the luminous efficiency and stability of the device.
Furthermore, in the field of organic synthetic chemistry, it is an extremely important synthetic building block. Organic chemists often use it to participate in the construction of complex organic molecules. Its unique structure and reactivity can participate in various reactions such as nucleophilic substitution, electrophilic substitution, and cyclization, providing an effective path for the synthesis of organic compounds with complex structures and specific functions. In the total synthesis of many natural products, 2-methyl-1H-pyrrole-3-carboxylate ethyl ester is a key intermediate, which helps to achieve the precise construction of complex molecular frameworks and promotes the development of organic synthesis chemistry.

To prepare 2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester, there are many methods, and there are several common ones mentioned above.
First, it can be obtained by esterification of 2-methyl-1H-pyrrole-3-carboxylic acid and ethanol under acid catalysis. Concentrated sulfuric acid, p-toluenesulfonic acid, etc. are often used as catalysts. In the reaction system, carboxylic acid and ethanol are mixed in appropriate proportions, an appropriate amount of catalyst is added, and reflux is heated. After the reaction is completed, the product is purified through neutralization, washing with water, separation, drying, and distillation. In this process, the amount of catalyst, reaction temperature and time need to be precisely controlled. Excessive dosage may cause an increase in side reactions; if the temperature is too high and the time is too long, it will also cause unnecessary side reactions, which will affect the purity and yield of the product.
Second, halogenates can be used to react with compounds containing pyrrole structures. First, 2-methyl-3-halogenated pyrrole is prepared, then it reacts with sodium ethanol and carbon dioxide, and then acidifies and esterifies to obtain the target product. This path step is slightly complicated, but the reaction conditions can be flexibly adjusted to achieve better results. During the halogenation reaction, the choice of halogenating agent, reaction solvent and other factors have a great impact on the selectivity and yield of the product. Subsequent reactions with sodium ethanol and carbon dioxide should pay attention to the anhydrous and oxygen-free conditions of the reaction system, otherwise it is easy to cause the reaction to fail or form impurities.
Third, pyrrole derivatives are used as starting materials and transformed through a series of functional groups. For example, the pyrrole ring is modified first, and suitable substituents are introduced, followed by hydrolysis and esterification. This method requires in-depth understanding of the chemical properties of pyrrole, and the reaction conditions of each step need to be carefully optimized. When modifying the pyrrole ring, the activity of the reagents used and the selectivity of the reaction check point need to be considered, otherwise it is difficult to obtain the expected product.
In short, the synthesis of 2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester, different methods have advantages and disadvantages, according to actual needs, such as raw material availability, cost, product purity requirements, etc., choose the appropriate method, and optimize the reaction conditions in detail, in order to efficiently prepare the target product.

I look at your question, and I am inquiring about the market price of 2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester. However, the price of this chemical often varies due to various factors, making it difficult to determine.
First, the price of raw materials has a great impact. If the price of the raw materials required for the preparation of this ester fluctuates, the price of the finished product will also fluctuate. If the raw materials are not easy to obtain, or the price fluctuates due to origin, season, supply and demand, the price of this ester is also affected.
Second, the method of preparation is related to cost and price. If the process is simple, the cost may be low, and the price may be close to the people; if the process is complicated, special equipment, reagents are required, or energy consumption is quite large, the cost will increase and the market price will also be high.
Third, market supply and demand are the key factors. If there are many buyers, and the output is limited, the supply is in short supply, and the price will rise; if the market is saturated and the supply is excessive, the price will fall.
Fourth, the difference between manufacturers also leads to price differences. Large factories have good reputation, high quality products, and the price may be slightly higher; small factories compete for the market, and the price may be lower. And transportation, storage and other costs also affect the final selling price.
In summary, in order to know the exact market price of 2-methyl-1H-pyrrole-3-carboxylate, it is necessary to carefully investigate the raw materials, processes, supply and demand, and manufacturers, and inquire in real time in the chemical raw material market, suppliers, etc., to obtain a more accurate price.

2-Methyl-1H-pyrrole-3-carboxylic acid ethyl ester, this is an organic compound. Its storage conditions are quite important, and it is related to the stability and quality of the substance.
According to the method of "Tiangong Kaiwu", when it comes to the storage of things, it depends on their properties. This ethyl ester is sensitive to light, moisture, and heat. Therefore, when hiding, it should be protected from light for the first time. It should be placed in a dark place. If it is stored in a dark bottle, it can be protected from direct sunlight and prevent it from deteriorating due to photochemical reactions.
Second, it is moisture-proof. Moisture is easy to cause hydrolysis of compounds and other changes, so it should be stored in a dry place. A desiccant, such as silica gel, can be placed in the reservoir to absorb moisture and keep it dry.
Furthermore, the temperature should also be paid attention to. Overheating will greatly increase the molecular activity, or cause reaction to cause deterioration. It should be stored in a cool place, the temperature should not exceed 25 ° C, if it can be controlled between 15-20 ° C, it is more suitable.
And the storage place should be away from fire, heat sources and strong oxidants. Because it is an organic ester, it is flammable and dangerous to fire or hot topic. Mixing with oxidants can also easily cause violent reactions.
In short, 2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester needs to be protected from light, dry, cool, and protected from fire, heat and oxidants, so as to survive for a long time and maintain its quality.