2 Acetylpyrrole
pyridine pyrrole pyrazine piperidine piperazine

2-Acetylpyrrole

    Specifications

    HS Code

    690677

    Name 2-Acetylpyrrole
    Molecular Formula C6H7NO
    Molecular Weight 109.13 g/mol
    Appearance Yellow - brown liquid
    Odor Characteristic odor
    Boiling Point 212 - 214 °C
    Melting Point 21 - 23 °C
    Density 1.079 g/cm³ (at 20 °C)
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in ethanol, ether, etc.
    Flash Point 94 °C
    Pka 16.5 (estimated)

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    General Information
    Where to Buy 2-Acetylpyrrole in China?
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    Frequently Asked Questions

    As a leading 2-Acetylpyrrole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of Acetylpyrrole?
    2-Acetyl pyrrole is also an organic compound. It has a wide range of uses and has important applications in various fields.
    First and foremost in the field of medicine. 2-Acetyl pyrrole is a key intermediate in the synthesis of many drugs. Take some drugs with antibacterial and anti-inflammatory effects as an example. In its synthesis path, this compound is like the cornerstone of building a pavilion. After a series of delicate chemical reactions, it is ingeniously combined with other substances, and finally an effective drug ingredient is cast, which contributes to healing diseases and protecting health.
    Furthermore, in the field of materials science. 2-Acetyl pyrrole can participate in the creation of polymer materials. Due to its special chemical structure, it can endow materials with different properties. For example, to improve the stability and plasticity of materials, it plays an indispensable role in the preparation of many materials such as electronic devices and plastic products, and helps to optimize material properties to meet the needs of different scenarios.
    It can also be seen in the field of fragrances. 2-Acetylpyrrole can be used as a fragrance additive because it can emit a unique smell. After being prepared by a perfumer, it can be integrated into various flavors and fragrances, adding a unique aroma to perfumes, food fragrances, etc., and enriching the olfactory experience.
    In the field of organic synthesis chemistry, 2-Acetylpyrrole is often an important raw material for organic synthesis. Chemists use their active chemical properties to carry out various complex synthesis reactions, expand the variety of organic compounds, promote the research and development of organic chemistry, and open up paths for the creation of new substances.
    In short, 2-acetyl pyrrole plays a key role in many fields such as medicine, materials, flavors, and organic synthesis due to its unique chemical properties. It is indeed a valuable compound in the field of chemistry.
    What are the physical properties of Acetylpyrrole?
    2-Acetyl pyrrole is an organic compound. It has specific physical properties and is described below.
    Looking at its appearance, at room temperature, it is mostly white to light yellow crystalline powder, uniform and delicate, like a delicate frost powder, with a warm and soft color.
    As for its melting point, the melting point is about 82-84 ° C. When the temperature gradually rises at this time, the originally solid 2-acetyl pyrrole, like the ice and snow in spring when meeting the warm sun, slowly melts into a liquid state, changing from a regular solid state to a liquid state. Its boiling point is about 260 ° C, and at higher temperatures, it turns into a gaseous state to escape.
    In terms of solubility, 2-acetyl pyrrole exhibits a unique affinity in organic solvents. It is soluble in organic solvents such as ethanol, ether, and chloroform. In ethanol, it is like a wanderer returning home, rapidly dispersing and dissolving, and blending with ethanol to form a uniform solution system. However, in water, its solubility is very small, just like the incompatibility of oil and water, it can only be dispersed in a very small amount, and it is difficult to form a homogeneous phase.
    In addition, 2-acetyl pyrrole has a certain degree of volatility. In air, although it is slow, it can gradually evaporate. Its steam has a slightly special smell, not pungent and strong, but faintly exudes a unique organic smell, just like the subtle fragrance of medicine escaping from an ancient pharmacy, which attracts people to explore. These physical properties enable 2-acetyl pyrrole to display its capabilities in many fields such as organic synthesis and medical chemistry, adding a different color to the wonders of chemistry.
    What is the chemistry of 2-Acetylpyrrole?
    2-Acetyl pyrrole is one of the organic compounds. Its properties are unique and have unique chemical properties.
    In terms of its physical properties, 2-acetyl pyrrole is either a solid or a liquid at room temperature, depending on its purity and external conditions. Looking at its color, it is often colorless to light yellow, and has a certain volatility, with a specific odor.
    In terms of chemical properties, this compound contains pyrrole rings and acetyl groups. Pyrrole rings are aromatic, giving them a certain stability. However, because the nitrogen atom on the ring has lone pairs of electrons, it can participate in many reactions. Such as the electrophilic substitution reaction, the electron cloud density of the pyrrole ring is higher, and it is more susceptible to the attack of electrophilic reagents. And the electron cloud on the nitrogen atom can be dispersed on the ring, making the reaction more likely to occur at a specific location of the pyrrole ring.
    Furthermore, the presence of acetyl groups also affects its chemical behavior. Acetyl groups are electron-absorbing groups, which can change the electron cloud density of the pyrrole ring, which in turn affects the activity and selectivity of electrophilic substitution reactions. At the same time, acetyl groups can participate in many typical reactions of carbonyl groups, such as addition reactions with nucleophiles. It can undergo condensation reactions with alcohols under acidic or basic catalysis to generate corresponding acetals or hemiacetals. < Br >
    Because of its structure containing carbon-nitrogen bonds and carbon-carbon bonds, under specific conditions, such as high temperature and strong oxidant action, these chemical bonds can break, initiate oxidation, cracking and other reactions, resulting in different products. 2-Acetyl pyrrole has rich and diverse chemical properties and can be used as a key intermediate in the field of organic synthesis. It is used for the preparation of various complex organic compounds and is important for chemical research and industrial production.
    What are the synthesis methods of 2-Acetylpyrrole?
    The synthesis method of 2-acetyl pyrrole has been studied by many parties in ancient times, and today I will describe it in detail.
    First, pyrrole and acetic anhydride are used as raw materials. In a suitable reaction vessel, put an appropriate amount of pyrrole and slowly add acetic anhydride. This process needs to be carefully controlled and usually maintained in a mild temperature range. If the temperature is too high, side reactions will occur, and if it is too low, the reaction will be slow. At the same time, an appropriate amount of catalyst, such as some Lewis acids, can be added to promote the smooth progress of the reaction. The amount of catalyst needs to be precisely controlled, and too much or too little will affect the reaction effect. After the reaction is completed, through a series of separation and purification techniques, such as distillation, recrystallization, etc., pure 2-acetyl pyrrole can be obtained.
    Second, pyrrole and acetyl chloride can also be used as starting materials. First, pyrrole is dissolved in a suitable organic solvent, which must not interfere with the reaction system and can dissolve the reactants well. Then, under the condition of low temperature and stirring, acetyl chloride is added dropwise. The purpose of low temperature is to prevent the reaction from being too violent and causing the product to be impure. During the reaction process, pay close attention to the reaction phenomenon. When the reaction is over, separate and purify according to the previous method to remove impurities and obtain the target product.
    Third, pyrrole and ethyl acetate can also be synthesized as raw materials. This reaction often requires the assistance of a specific alkaline catalyst. Mix pyrrole, ethyl acetate and an alkaline catalyst in an appropriate proportion and react at a certain temperature and pressure. The alkaline catalyst can activate the reactants and promote the reaction to proceed in the direction of generating 2-acetyl pyrrole. After the reaction, the product is refined by means of extraction, distillation, etc., to obtain high-purity 2-acetyl pyrrole.
    These several synthesis methods have their own advantages and disadvantages. In practical application, when considering the availability of raw materials, cost, product purity requirements and many other factors, make a careful choice.
    What is the price range of Acetylpyrrole in the market?
    2-Acetyl pyrrole is in the market, and its price range is quite difficult to determine. The price of this product often varies for many reasons. The number of producers is small, and the supply and demand of the market can make the price different.
    If it has a wide range of origins, a large number of producers, and the market's demand is not very strong, the price may tend to be flat or low. However, if the product is scarce, and the market wants to cut it, the price must rise.
    In addition, the quality of its quality is also related to the price. Those with good quality, the price is always high; those with poor quality, the price may be low. Furthermore, the number of buyers also has an impact. If buyers gather and compete for this product, the price will rise; if there are few buyers, the price will not be high.
    According to normal circumstances, the price of 2-acetyl pyrrole is between a few yuan and a few tens of yuan per gram. However, this is only a rough estimate. In fact, it may vary greatly depending on time and place, and changes in the market. To know the exact price, you should carefully observe the market situation and consult all merchants.