2,5-Dioxo-3-pyrroline~1H-Pyrrole-2,5-dione

The chemical substance corresponding to 2%2C5+-+Dioxo+-+3+-+pyrroline%7E1H+-+Pyrrole+-+2%2C5+-+dione is 1H-pyrrole-2,5-dione, which is also known as maleimide. This substance consists of a five-membered nitrogen-containing heterocycle, with a carbonyl group attached to each of the 2 and 5 positions on the ring.
Looking at its structure, it is based on a pyrrole ring, which is an unsaturated five-membered heterocycle containing a nitrogen atom. Carbonyl groups at the 2 and 5 positions on the ring give the substance specific chemical activity. Carbonyl groups are polar and can participate in many chemical reactions, such as nucleophilic addition.
In its structure, the lone pair electron of the nitrogen atom makes the pyrrole ring have a certain alkalinity, but due to the influence of the ring conjugation system, the alkalinity is weak. This structural property makes 1H-pyrrole-2,5-dione widely used in the field of organic synthesis, often used as a diene-friendly body to participate in Diels-Alder reactions, etc., to construct complex organic molecular structures.

2%2C5+-+Dioxo+-+3+-+pyrroline%7E1H+-+Pyrrole+-+2%2C5+-+dione that is, 2,5-dioxo-3-pyrroline~ 1H-pyrrole-2,5-dione, also known as maleimide. Its main uses are as follows:
First, in the field of organic synthesis, it is often used as a key intermediate. It can be reacted with many nucleophiles, such as amines, alcohols, etc., to prepare a series of organic compounds with special structures and functions. This is because the carbonyl group and double bond in the molecule have high reactivity, and can participate in various types of chemical reactions, such as nucleophilic addition, cyclization, etc., providing an effective path for the synthesis of complex organic molecules.
Second, in the field of materials science, maleimide can be used to prepare high-performance polymer materials. By copolymerizing with other monomers, it can endow polymer materials with excellent properties, such as improving the thermal stability, mechanical properties and chemical stability of the material. The prepared polymer materials have a wide range of applications in aerospace, electronics and other fields. For example, in the aerospace field, the high temperature resistance and high strength of materials are strictly required, and polymer materials containing maleimide structure can meet such needs.
Third, in the field of biomedicine, maleimide can be used as a modified group for drug molecules due to its unique chemical structure. By linking maleimide to drug molecules, it can improve the pharmacokinetic properties of drugs, such as improving the solubility and stability of drugs, and achieving targeted delivery of drugs. In addition, in protein modification research, maleimide can specifically react with cysteine residues in proteins, thereby labeling and immobilizing proteins, which is helpful for biomedical research.

The substance corresponding to the 2%2C5+-+Dioxo+-+3+-+pyrroline%7E1H+-+Pyrrole+-+2%2C5+-+dione is 1H-pyrrole-2,5-dione, which has the following physical properties:
Its appearance is often white to light yellow crystalline powder, like fine powder, uniform texture. Under normal temperature and pressure, it exists stably in the solid state, which is due to the intermolecular force to have this physical state.
Smell, this substance has a weak smell, almost odorless, and it is difficult to detect obvious odor characteristics even if it is finely smelled.
The melting point is between 130-134 ° C. When heated to this temperature range, the molecules obtain enough energy, and the lattice structure begins to disintegrate, then the solid state gradually melts into a liquid state. < Br >
In terms of solubility, it is slightly soluble in water, and the interaction between water molecules and the substance molecules is weak, only some molecules can be dispersed in water; but it is easily soluble in common organic solvents, such as ethanol, acetone, etc. In organic solvents, by virtue of the interaction with solvent molecules, it can be uniformly dispersed to form a solution.
The density of this substance is about 1.52 g/cm ³, which reflects the mass contained in its unit volume and is slightly higher than that of common organic substances, suggesting that its molecular arrangement is relatively close. The physical properties of 1H-pyrrole-2,5-dione are closely related to its molecular structure and play a key role in many chemical and related applications, determining the way it participates in chemical reactions and its behavior in different systems.

2%2C5+-+Dioxo+-+3+-+pyrroline%7E1H+-+Pyrrole+-+2%2C5+-+dione is 1H-pyrrole-2,5-dione (also known as maleimide), the following is the preparation method described in detail by Ru:
First, maleic anhydride and ammonia are used as raw materials. Maleic anhydride is an important raw material for organic synthesis and has active chemical properties. Ammonia is also a common chemical reagent. Mix maleic anhydride and ammonia in an appropriate proportion, and under suitable temperature and pressure, the two can react. After addition, the nitrogen atom of ammonia is connected to the carbonyl carbon of maleic anhydride, and then dehydrated and cyclized, resulting in 1H-pyrrole-2,5-dione. This reaction condition is relatively mild, easy to control, and is a commonly used method in industrial production. The reaction process requires attention to the ratio of temperature and reactants. If the temperature is too high or too low, it may affect the reaction rate and product purity; if the ratio is not correct, the raw materials may be wasted or the product yield will be low.
Second, it can be prepared by the reaction of succinic acid with urea. succinic acid is a dicarboxylic acid, and urea is a nitrogen-containing compound. Place the two in a specific reaction system, add an appropriate catalyst, and heat the reaction. The condensation reaction between succinic acid and urea first occurs, and gradually forms a cyclic structure, eventually generating 1H-pyrrole-2,5-dione. This method is more common in raw materials and relatively low in cost. However, in the reaction process, the choice and dosage of catalysts are crucial. Appropriate catalysts can accelerate the reaction process and increase the yield. Improper dosage may lead to side reactions and affect the quality of the product. At the same time, the control of reaction temperature and time cannot be ignored, and it is necessary to accurately grasp in order to achieve the desired reaction effect.

2% 2C5 - Dioxo - 3 - pyrroline (1H - Pyrrole - 2% 2C5 - dione) is also a chemical substance. During use, please pay attention to the general situation.
First, this substance has chemical activity, or other substances can cause reaction. Therefore, when using it, you must check the compatibility of its surrounding objects. If its nature is unknown, do not mix unknown substances to prevent accidental reactions and dangerous reactions, such as explosion, release of toxic substances.
Second, the toxicity of this substance is also serious. Or inhalation, skin contact, food, etc., endangering human health. Therefore, when operating, you must take preventive measures. For example, in good working conditions, appropriate anti-dumping equipment, such as gas masks, gloves, eyes, etc., should be equipped to prevent it from invading people.
Third, the existence of this object is also investigated. It is also necessary to store oxidizing and original substances in different ways to prevent their properties from being changed or safety accidents.
Fourth, during use, the operation should be fine, and this object should not be released. If it is accidentally released, it should be cleaned according to the correct method. And after the operation is completed, it must be properly handled, and it should not be poured inadvertently, and it should be placed in the environment according to the phase. Therefore, when using this chemical substance, you must be careful to ensure safety.