2,5-Dimethyl-1-phenylpyrrole-3-carboxaldehyde

2% 2C5-dimethyl-1-phenylpyrrole-3-acetic acid, this compound is widely used in the fields of medicine and chemical industry.
In the process of pharmaceutical research and development, it plays the role of a key intermediate. Due to its unique chemical structure, new compounds with specific biological activities can be constructed by chemical modification. Many studies have shown that compounds containing such structures have potential therapeutic effects on specific diseases. For example, in the field of anti-tumor drug development, researchers have successfully obtained compounds with significant inhibitory activity on some tumor cells by optimizing and modifying its structure. This provides a new strategy and direction for overcoming cancer problems.
In the chemical industry, it is an important raw material for the preparation of special polymer materials. Due to its structural properties, it can give polymer materials special properties. For example, when adding it in the preparation of high-performance engineering plastics, it can enhance the thermal stability and mechanical properties of plastics, and broaden its application range in high temperature and high stress environments. Such high-performance materials are indispensable in fields such as aerospace and automobile manufacturing.
To sum up, 2% 2C5-dimethyl-1-phenylpyrrole-3-acetic acid plays an important role in the fields of medicine and chemical industry with its unique chemical structure, promoting technological innovation and product upgrading in related fields.

To prepare 2,5-dimethyl-1-phenylpyrrole-3-carboxylic acid, there are various methods.
First, the corresponding pyrrole derivative can be obtained through a specific substitution reaction. First, take a suitable pyrrole parent and make it meet with halogenated methyl reagents under specific conditions, such as halomethane, so that methyl groups are ingeniously introduced into the 2nd and 5th positions of the pyrrole ring. In this process, it is necessary to precisely control the temperature, solvent and catalyst of the reaction to make the reaction proceed in the expected direction and ensure the accuracy of the substitution position. After the 2,5-dimethyl pyrrole derivative is obtained, a phenyl group is introduced into the pyrrole ring at the 1st position. The phenyl group can be successfully connected to the first position by arylation reaction, using phenyl halide and pyrrole derivative as raw materials, with the help of appropriate metal catalysts and bases. Finally, for the 3 position of the pyrrole ring, with suitable carboxylation reagents, such as carbon dioxide or its equivalents, under specific reaction conditions, the carboxylation of the 3 position can be achieved to obtain the target product 2,5-dimethyl-1-phenylpyrrole-3-carboxylic acid.
Second, the pyrrole ring can be constructed by yourself. Select the raw materials containing suitable substituents, such as amino ketones and β-ketoic esters containing 2 methyl groups and 1 phenyl group, and make the two under the action of acidic or basic catalysts, through cyclization and condensation reaction, a pyrrole ring is constructed in one step, and at the same time, methyl is carried out at the 2,5 position of the pyrrole ring, and phenyl is carried out at the 1 position. After that, the obtained pyrrole product is transformed into a suitable functional group, and a suitable group is converted into a carboxyl group, and the target 2,5-dimethyl-1-phenylpyrrole-3-carboxylic acid can also be obtained. The key to this path lies in the optimization of the conditions of the cyclization condensation reaction and the selective control of the subsequent functional group conversion.
Third, a stepwise splicing strategy can also be used. The fragment containing part of the target structure is first synthesized, such as the fragment containing 2,5-dimethyl pyrrole and the fragment containing phenyl and potential carboxyl groups, respectively. Then, the two are connected through a coupling reaction to form a complete 2,5-dimethyl-1-phenylpyrrole-3-carboxylic acid structure. This strategy requires careful design of the synthetic route of the fragment to ensure the efficiency and selectivity of the coupling reaction in order to achieve the effective synthesis of the target product.

2% 2C5-dimethyl-1-phenylpentyne-3-ene is an organic compound, and its physical properties are described as follows:
1. ** State and color **: Under normal circumstances, this compound is mostly colorless to light yellow liquid form, clear texture. In the pure state, there is no significant color, but it may be slightly yellow due to the mixing of impurities or the influence of light, oxidation and other factors. This characteristic is quite common in many organic alkynes. Due to the existence of unsaturated bonds, it is relatively easy to be disturbed by external conditions.
2. ** Odor **: With a special aromatic smell, this smell is derived from the phenyl group in the molecular structure. The presence of phenyl groups gives the compound a unique smell, which is slightly similar to the smell of common aromatic hydrocarbons. However, due to the coexistence of alkynyl and alkenyl groups in the molecule, its smell is unique. Experienced chemical practitioners can use this to preliminarily identify.
3. ** Melting boiling point **: Due to the existence of a conjugated system and the unsaturated structure of alkynyl and alkenyl groups in the molecule, its boiling point is relatively high. Specifically, at standard atmospheric pressure, the boiling point is between 180 and 200 ° C. Because the conjugated system enhances the intermolecular force, more energy is required to overcome it, causing the molecule to break away from the liquid state and transform into a gaseous state. The melting point is relatively low, about -20 ° C to -10 ° C, indicating that the compound is a liquid at room temperature and solidifies at low temperatures.
4. ** Density **: The density is slightly higher than that of water, about 0.95 - 1.05 g/cm ³. This is due to the number and arrangement of carbon and hydrogen atoms in the molecule, which makes its unit volume mass larger than that of water. If mixed with water, it will sink to the bottom of the water. This property can be used as an important basis for the separation and identification of the compound.
5. ** Solubility **: This substance is insoluble in water because water is a polar molecule, and 2% 2C5-dimethyl-1-phenylpentyne-3-ene is a non-polar or weakly polar molecule. According to the principle of "similar miscibility", the two are difficult to miscible. However, it is soluble in many organic solvents, such as ethanol, ether, chloroform, etc. In ethanol, it can be miscible in any ratio, which provides a convenient dissolution and reaction environment for it in organic synthesis and related experimental operations.

2% 2C5-dimethyl-1-phenylpentyne-3-ene is an organic compound, which has the following chemical properties:
1. ** Addition reaction **: Due to the carbon-containing carbon double bond and the carbon-carbon triple bond, this compound can undergo an addition reaction. Under suitable conditions, the carbon-carbon double bond can be added with electrophilic reagents such as hydrogen, halogen, and hydrogen halide. For example, under the action of a catalyst such as nickel, it can be added with hydrogen to form a product of complete hydrogenation of the carbon-carbon double bond. If there is sufficient hydrogen, the carbon-carbon triple bond can also be further hydrogenated. The carbon-carbon triple bond can not only be added to the molecular reagent, but also can be added to the two-molecule reagent according to different conditions, such as addition to the two-molecule hydrogen halide.
2. ** Oxidation reaction **: The carbon-carbon double bond and the carbon-carbon triple bond in the molecule can be oxidized. In case of strong oxidants such as acidic potassium permanganate solution, the carbon-carbon double bond will be oxidized and broken. Depending on the groups connected to the double bond carbon atom, the product may be carboxylic acid, ketone, etc.; in case of acidic potassium permanganate solution, the carbon-carbon triple bond will also be oxidized, and the three bond will be broken to form an oxygenated compound. At the same time, although the benzene ring of this compound is relatively stable, it may also be oxidized under specific strong oxidation conditions, but the oxidation of benzene ring is relatively difficult
3. ** Polymerization reaction **: In view of its unsaturated bond, under suitable initiators and conditions, polymerization can occur. Carbon-carbon double bonds can form polymer compounds through addition polymerization. This polymerization reaction has potential application value in the field of material synthesis and can be used to prepare polymer materials with specific properties.
4. ** Substitution reaction **: The hydrogen atom on the benzene ring can undergo a substitution reaction. Because the benzene ring has aromatic properties, it can carry out electrophilic substitution reactions, such as halogenation reactions. Under the catalysis of iron or iron halide, it can be substituted with halogens, and halogen atoms replace the hydrogen on the benzene ring. Nitrification reactions can also occur. Under the action of concentrated sulfuric acid and concentrated nitric acid mixed acid, nitro groups are introduced into the benzene ring; sulfonation reactions can also be carried out.

I look at your words, but I am inquiring about the market price of 2,5-dimethyl-1-phenylpyrrole-3-acetonitrile. However, the price of this chemical product varies with quality, quantity, source and market conditions, and it is difficult to determine the value.
If you want to ask for the general idea, the fluctuation of the price of various chemical raw materials in the market depends on supply and demand, craftsmanship, transportation and storage. This 2,5-dimethyl-1-phenylpyrrole-3-acetonitrile, if it is of ordinary quality and quantity, is not huge. The price of chemicals purchased in the market may vary from a few gold to tens of gold per gram. < Br >
However, if you want high-purity products, or need to use them in large quantities, the price will increase. And in different places, due to differences in taxes and logistics, the price also varies. In the chemical market, the market changes from time to time, and today's price cannot be met tomorrow. To know the exact price, you should consult the chemical raw material supplier, or check it on the chemical trading platform, to get a near-real value.