2 4 Dimethyl 1h Pyrrole 3 Carboxylic Acid Ethyl Ester
pyridine pyrrole pyrazine piperidine piperazine

2,4-Dimethyl-1H-Pyrrole-3-carboxylic acid ethyl ester

    Specifications

    HS Code

    613779

    Chemical Formula C9H13NO2
    Molar Mass 167.205 g/mol
    Appearance Solid (usually)
    Physical State At Room Temp Solid
    Boiling Point Data may vary, specific value depends on purity etc.
    Melting Point Data may vary, specific value depends on purity etc.
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some common organic solvents like ethanol, dichloromethane
    Odor Typically has a characteristic organic odor
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
    Where to Buy 2,4-Dimethyl-1H-Pyrrole-3-carboxylic acid ethyl ester in China?
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    Frequently Asked Questions

    As a leading 2,4-Dimethyl-1H-Pyrrole-3-carboxylic acid ethyl ester supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of ethyl 2,4-dimethyl-1H-pyrrole-3-carboxylate?
    2% ethyl 2C4-dimethyl-1H-imidazole-3-carboxylate. This is an organic compound. Its chemical properties are quite important and have applications in many fields.
    Looking at its structure, it is endowed with unique chemical properties due to the specific functional groups such as imidazole ring and ester group. In terms of reactivity, the nitrogen atom of the imidazole ring has a lone pair of electrons, which is alkaline and can react with electrophilic reagents such as acids. For example, it can form salts with protonic acids, and this property can be used to improve drug solubility and stability in some drug synthesis.
    The ester group can undergo hydrolysis reaction under basic or acidic conditions. Under basic conditions, it will hydrolyze to form corresponding carboxylic salts and alcohols; under acidic conditions, it will hydrolyze to carboxylic acids and alcohols. This hydrolysis reaction is an important conversion step in organic synthesis, through which functional groups can be introduced or converted.
    Furthermore, the presence of methyl groups in this compound will affect the spatial structure and electron cloud distribution of the molecule. Methyl groups act as power supply groups, which can increase the electron cloud density of the imidazole ring, thereby affecting its reactivity and selectivity.
    At the same time, because of its specific chemical properties, it can be used as a potential pharmaceutical intermediate in the field of medicinal chemistry to construct molecular structures with specific biological activities; in materials science, it may be able to participate in the preparation of polymer materials with special properties. In conclusion, the chemical properties of 2% 2C4-dimethyl-1H-imidazole-3-ethyl carboxylate are rich and diverse, which lays the foundation for its application in different fields.
    What are the synthesis methods of 2,4-dimethyl-1H-pyrrole-3-carboxylate ethyl ester?
    To prepare 2,4-dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester, there are many methods, each has its advantages and disadvantages, and should be carefully selected.
    First, it can be obtained by esterification of the corresponding pyrrole derivative. First take 2,4-dimethyl-1H-pyrrole-3-carboxylic acid, place it in a reactor, add an appropriate amount of ethanol, use concentrated sulfuric acid as a catalyst, and heat it up to a suitable temperature, usually at 60-80 degrees Celsius, when refluxing and stirring for several times. During this period, pay close attention to the reaction process, which can be monitored by thin-layer chromatography. After the reaction is completed, cool, pour the reaction solution into ice water, neutralize it to neutral in sodium bicarbonate solution, extract it with an organic solvent, such as ethyl acetate, collect the organic phase, dry it with anhydrous sodium sulfate, and then steam to remove the solvent. The crude product can be obtained and purified by column chromatography to obtain a pure product of 2,4-dimethyl-1H-pyrrole-3-carboxylate. The raw materials of this method are relatively easy to obtain, the reaction conditions are relatively mild, but the concentrated sulfuric acid is highly corrosive and the post-treatment is cumbersome.
    Second, 2,4-dimethyl pyrrole and halogenated ethyl acetate are used as raw materials and react under alkali catalysis. In a reaction vessel, dissolve 2,4-dimethyl pyrrole in a suitable organic solvent, such as tetrahydrofuran, add an appropriate amount of alkali, such as potassium carbonate, stir well, slowly drop halogenated ethyl acetate, and react at room temperature or slightly higher temperature. After the reaction is completed, solid impurities are removed by filtration, the filtrate is concentrated, and separated and purified by silica gel column chromatography. The method has simple steps and acceptable yield. However, halogenated ethyl acetate is more toxic, so it needs to be handled with caution.
    Third, pyrrole rings can be constructed through multi-step reactions and ethyl ester groups can be introduced. First, suitable alters, ketones, amines, etc. are used as starting materials to form pyrrole rings through condensation, cyclization, etc., and then ethyl ester groups are introduced by esterification or other methods. Although this approach is complicated, the reaction route can be flexibly adjusted, which is suitable for situations where there are special requirements for the purity and structure of the product.
    All kinds of synthesis methods have their own applications. According to actual needs, consider the availability of raw materials, cost, yield, purity and other factors, weigh the advantages and disadvantages, and choose the best to prepare 2,4-dimethyl-1H-pyrrole-3-carboxylate.
    What is the main use of ethyl 2,4-dimethyl-1H-pyrrole-3-carboxylate?
    2% 2C4-dimethyl-1H-imidazole-3-carboxylate ethyl ester, this substance has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate. Due to its unique chemical activity and stability, this structure can participate in many complex organic synthesis reactions, assist pharmaceutical developers in creating new drug molecules, or optimize the chemical structure of existing drugs to improve efficacy and reduce toxic and side effects.
    In the field of materials science, it also has important applications. Due to its structural properties, it may endow materials with special properties. For example, when preparing some functional polymer materials, introducing them into the polymer structure can improve the thermal stability, mechanical properties or electrical properties of the material, and then expand the application of the material in different fields.
    Furthermore, in the field of organic synthetic chemistry, it is often used as a catalyst or ligand. With its own specific electronic effect and steric resistance, it can effectively promote the progress of specific chemical reactions, improve the selectivity and efficiency of the reaction, and is of great significance for the synthesis of high-purity, specific structure organic compounds. This is the main use of 2% 2C4-dimethyl-1H-imidazole-3-carboxylate ethyl ester.
    What is the market prospect of ethyl 2,4-dimethyl-1H-pyrrole-3-carboxylate?
    2% 2C4-dimethyl-1H-imidazole-3-carboxylate ethyl ester, this product has broad prospects in the field of pharmaceutical and chemical industry.
    Looking at the current market, in the field of pharmaceutical creation, it is a key intermediate. Many new antibacterial and antiviral drugs are developed based on it. In the case of antibacterial drugs, after clever chemical modification, new products that are effective against drug-resistant bacteria can be derived. Due to the increasing resistance of bacteria, the demand for such antimicrobials with novel structures is increasing, so 2% 2C4-dimethyl-1H-imidazole-3-carboxylate has great market potential in this field.
    In the field of chemical materials, it can participate in the synthesis of special polymers. The resulting polymer may have excellent heat resistance and chemical corrosion resistance, and is widely used in cutting-edge fields such as aerospace and high-end electronic equipment. Aerospace equipment needs to withstand extreme environments, and this polymer can just meet its strict requirements for high performance of materials. With the rapid development of related high-end industries, the demand for this chemical raw material is also rising.
    However, its market also has challenges. The synthesis process is complex and the cost remains high, limiting its large-scale application. And environmental regulations are stricter, and the production process must meet high standards. To expand the market, it is necessary to optimize the synthesis process, reduce costs and increase efficiency, and strictly abide by environmental protection guidelines.
    Overall, the 2% 2C4-dimethyl-1H-imidazole-3-carboxylate ethyl ester market has a bright future, but practitioners also need to work on both technology and environmental protection to enjoy its market dividends.
    What are the precautions for the storage and transportation of 2,4-dimethyl-1H-pyrrole-3-carboxylate ethyl ester?
    2% 2C4-dimethyl-1H-imidazole-3-carboxylate ethyl ester should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its certain chemical activity, if heated or caused by chemical reactions, it will damage the quality of the medicine. Just like the storage of ancient times, grain should also be placed in a dry and ventilated place to keep it intact.
    It needs to be stored separately from oxidants, acids, bases, etc., and must not be mixed. This is because different chemical substances react occasionally, just like the ancient art of war, things that are incompatible with water and fire must be separated.
    When handling, it must be handled lightly to prevent damage to the packaging and containers. If the packaging of this medicine is broken, the medicine will come into contact with the external environment or change. Just like porcelain, it will be easily broken if handled carelessly.
    During transportation, it should be ensured that the container does not leak, collapse, fall or damage. The means of transportation must be clean, dry, and free of other chemicals. Just like a river, the hull of the ship must be strong and the cabin clean to ensure the safety of the goods. And when transporting, it must follow the specified route, and do not stop in densely populated areas and residential areas, just in case of leakage and endangering everyone. < Br >
    Storage and transportation of 2% 2C4-dimethyl-1H-imidazole-3-carboxylate ethyl ester requires caution at every step to ensure drug quality and transportation safety.