(1S,3aR,6aS)-Octahydrocyclopenta[c]pyrrole-1-carboxylic acid ethyl ester

Ethyl (1S, 3aR, 6aS) -octahydrocyclopento [c] pyrrole-1-carboxylate has a unique chemical structure. This compound is derived from the cyclopento [c] pyrrole skeleton, which has been modified by octahydro and shows a saturated state.
Looking at its structure, at the first position of cyclopento [c] pyrrole, there is a group of ethyl monocarboxylate. In this group, the carboxyl group is connected to ethanol by esterification to form an ester bond. The existence of this ester bond imparts specific chemical activity and physical properties to the compound. < Br >
On the skeleton of cyclopento [c] pyrrole, the stereoconfigurations of the 1st, 3a and 6a positions are S, R and S, respectively. The differences in the stereoconfigurations have significant effects on the biological activity, chemical reactivity and physical properties of the compounds.
The chemical structure of (1S, 3aR, 6aS) -octahydro cyclopento [c] pyrrole-1-carboxylate ethyl ester is composed of cyclopento [c] pyrrole skeleton, octahydro modification and the ethyl carboxylate group at the 1st position, and the specific stereoconfiguration adds unique chemical properties to it.

(1S, 3aR, 6aS) -octahydrocyclopento [c] pyrrole-1-carboxylate ethyl ester, this is an organic compound with important uses in many fields.
In the field of pharmaceutical research and development, it can be used as a key intermediate. Due to the unique structure of this compound, it may endow drugs with specific biological activities, enabling scientists to create new drugs. For example, in the development of drugs for neurological diseases, the molecular structure based on this may effectively regulate neurotransmitter transmission, which is helpful for the treatment of epilepsy, Parkinson's disease and other diseases; in the exploration of anti-tumor drugs, or by modifying the structure of this compound, a drug that can precisely act on specific targets of tumor cells can be designed to inhibit tumor cell proliferation and metastasis.
In the field of materials science, it also has potential applications. Due to its special chemical properties, it may participate in material synthesis and endow materials with unique properties. For example, in the preparation of polymer materials, adding this compound may change the mechanical properties and thermal stability of the material. If it is introduced into fibrous materials, it may improve the flexibility and wear resistance of fibers, and broaden the application of fibrous materials in textiles, industrial filter materials, etc.
In the field of organic synthetic chemistry, (1S, 3aR, 6aS) -octacyclopento [c] pyrrole-1 -ethyl carboxylate is often used as a key starting material. Chemists can modify and derive from various organic reactions to synthesize organic compounds with more complex structures and unique functions, enrich the library of organic compounds, and provide more material basis for the development of other fields.

To prepare (1S, 3aR, 6aS) -octahydrocyclopento [c] pyrrole-1-carboxylic acid ethyl ester, there are various methods. First, take the appropriate cyclopentene derivative, and the nitrogen-containing reagent, according to the method of nucleophilic addition. For example, cyclopentene with specific substituents and amine compounds, under suitable temperature and suitable catalyst, promote their addition to form nitrogen-containing intermediates. After that, the technique of hydrogenation is applied to this intermediate, hydrogen is added, and the hydrogenation catalyst is selected to saturate the double bond and increase the degree of hydrogenation. Then by esterification method, ethyl ester group is introduced, and the intermediate product containing carboxyl group is taken, which is co-reacted with ethanol and condensation agent to form (1S, 3aR, 6aS) -octahydrocyclopento [c] pyrrole-1 -carboxylic acid ethyl ester.
Another method, using cyclopentadiene as the starting material, first reacts with the dienophile through Diels-Alder to form a fused ring compound. The fused ring is then converted in a series of transformations, and the substituent on the ring is first modified to introduce nitrogen atoms, or by halogenation, aminolysis, etc. Then, it is also hydrogenated, so that the double bond in the ring gradually becomes a single bond, and the hydrogenated intermediate is obtained. Finally, by esterification, the carboxyl group and ethanol are formed into esters, and the target product is obtained.
Complex other method, starting with the nitrogen-containing five-membered heterocyclic precursor, through ring opening and ring closing changes. First, the precursor is opened, and an appropriate chain segment is introduced to modify its structure. After the ring closing reaction, the skeleton of cyclopentopyrrole is constructed. After the ring closing, hydrogenation, esterification and other steps are taken to achieve the purpose of hydrogenation and ethyl ester introduction in sequence, and finally (1S, 3aR, 6aS) -octacyclopento [c] pyrrole-1 -carboxylic acid ethyl ester. All kinds of production methods have their own advantages and disadvantages, and they need to be selected according to the ease of availability of raw materials, the simplicity of steps, and the high or low yield.

Ethyl (1S, 3aR, 6aS) -octacyclopento [c] pyrrole-1-carboxylate, the physical and chemical properties of this substance are particularly important. Its appearance is often colorless to light yellow liquid or solid, and this morphology is closely related to the surrounding temperature, pressure and other factors.
When it comes to solubility, it has good solubility in common organic solvents such as ethanol and chloroform, because the molecular structure is in line with the intermolecular forces of organic solvents. However, in water, its solubility is relatively limited, due to the difference in molecular polarity and water.
Boiling point and melting point are also important properties. Its boiling point is mostly within a certain temperature range, at which the molecular kinetic energy is sufficient to overcome the intermolecular forces and change from liquid to gaseous state. The melting point is related to the transition between solid and liquid states, and the specific value is affected by the close arrangement of molecules and the interaction force.
In addition, the chemical stability of (1S, 3aR, 6aS) -occyclopento [c] pyrrole-1-carboxylate ethyl ester cannot be ignored. Under normal conditions, its chemical properties are relatively stable. In case of extreme conditions such as strong acid, strong base or high temperature, the molecular structure may change, triggering chemical reactions, or hydrolysis, or substitution and addition reactions with other substances. This is because the functional groups in its molecules, such as ester groups, have specific reactivity. In short, knowing its physical and chemical properties in detail is of great significance in its preparation, storage, and application.

I have not heard the market price of " (1S, 3aR, 6aS) -Octahydrocyclopenta [c] pyrrole-1-carboxylic acid ethyl ester". This is a fine chemical substance, and its price is determined for many reasons.
First, the difficulty of preparing this substance affects its price. If the preparation method is complicated, it requires multiple steps of reaction, special reagents and conditions are used, and the yield is low, the cost will be high, and the price will rise accordingly.
Second, the market demand is also the key. If the demand for this substance is strong in the fields of pharmaceutical research and development, chemical synthesis, etc., and the supply is limited, its price should rise; if the demand is weak and the supply exceeds the demand, the price may drop.
Third, the price of raw materials also affects it. Raw materials are rare or expensive, resulting in rising costs and rising prices.
Fourth, the scale of production also has an impact. Large-scale production can reduce costs through scale effects, and prices may be close to the people; small-scale production, costs are difficult to reduce, and prices must be high.
In summary, without knowing the specific preparation process, market supply and demand, raw material prices and production scale of this compound, it is difficult to determine its price in the market. To know its exact price, you can consult chemical raw material suppliers, chemical reagent sellers, or check it on the chemical product trading platform.