1H-Pyrrole-3-carboxamide, 5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-

This is an organic compound, and its naming is quite complicated. According to the naming rules of organic chemistry, the core structure of this compound is 1H-pyrrole-3-formamide. There is a 4-fluorophenyl group at position 5, a 1-methylethyl group at position 2, and a phenyl group at position 4 of the nitrogen atom (N), and a phenyl group at position 4, and a 2- (2R, 4R) -tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl) ethyl group at position 1.
Looking at this structure, it is like a carefully constructed chemical "pavilion". The pyrrole ring is like the cornerstone of the pavilion, and the substituents on it are like the cornice of the pavilion, each in its own place and performing its own duties. 4-Fluorophenyl group has the characteristics of adding fluorine, 1-methyl ethyl group confers certain steric hindrance and hydrophobicity, the existence of diphenyl group may have a significant impact on its electron cloud distribution and conjugation system, and 2 - (2R, 4R) -tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl) ethyl The introduction of the pyran ring structure may give the compound unique reactivity and biological activity. This structure is complex and delicate, and the interaction of various parts jointly determines the physical, chemical and biological properties of the compound.

1H-pyrrole-3-formamide, 5- (4-fluorophenyl) -2- (1-methylethyl) -N, 4-diphenyl-1- (2- (2R, 4R) -tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl) ethyl) This compound has the following physical properties:
It is usually in solid form, often in white or off-white powder shape, and has a fine texture. Due to the presence of many aromatic rings and polar groups in the molecular structure, it has a specific melting point, which is about [X] ° C. This melting point is of great significance to the purity and identification of the compound, and its purity can be preliminarily determined by melting point determination.
The compound has unique solubility and exhibits good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide. It can be successfully dissolved to form a uniform solution, but the solubility in water is very small. This difference in solubility has a significant impact on the separation, purification and preparation development of compounds. Good solubility in organic solvents provides convenience for chemical synthesis and reaction operations, while the slightly soluble water characteristics suggest that the preparation process requires special means to improve its bioavailability.
In terms of density, it is about [X] g/cm ³. Although the density is not directly related to its chemical activity, it is of great significance in practical applications such as material handling, storage and preparation molding, which affects the quantity, mixing and preparation specifications of materials.
Its stability is also concerned, and it can exist stably under normal temperature, dry and dark environment. However, in case of strong acid, strong base or high temperature conditions, amide bonds, ester bonds, etc. in the molecular structure may be hydrolyzed or other chemical reactions may occur, resulting in structural changes and loss of activity. Therefore, when storing and using, it is necessary to strictly control the environmental conditions to ensure its stability.

This chemical substance is named 5- (4-fluorophenyl) -2 - (1-methylethyl) -N, 4-diphenyl-1 - (2 - ((2R, 4R) -tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl) ethyl) -1H-pyrrole-3-formamide, but it has not been seen in "Tiangong Kaiwu". "Tiangong Kaiwu" is a masterpiece of science and technology written by Ying Xing in the Song Dynasty of the Ming Dynasty. It details the production technologies of agriculture and handicraft industry. It is detailed in the achievements of material culture in ancient China. However, it focuses on common practical technologies at that time, mostly involving grain cultivation, textiles, ceramics, smelting and other fields, and the synthesis, properties and uses of this complex organic compound are beyond the reach of chemical cognition and technology in the era of Tiangong Kaiwu. This compound may be derived from modern organic chemistry research and may have potential applications in medicine, materials science and other fields. For example, in the field of medicine, or designed and synthesized to achieve specific pharmacological activities, as a lead compound for drug research and development; in materials science, or because of its unique chemical structure, endowing materials with special properties.

To prepare 1H - Pyrrole - 3 - carboxamide, 5 - (4 - fluorophenyl) - 2 - (1 - methylethyl) - N, 4 - diphenyl - 1 - (2 - (2R, 4R) - tetrahydro - 4 - hydroxy - 6 - oxo - 2H - pyran - 2 - yl) ethyl), the method is as follows.
First take appropriate starting materials, such as fluorophenyl derivatives, isopropyl substituents and tetrahydropyran ketones with specific chirality. According to the ancient concept of organic synthesis, when the raw materials interact under suitable reaction conditions.
In the reaction vessel, select a suitable solvent, such as a non-protonic organic solvent, to assist in the dissolution of the raw materials and the reaction. Adjust to the appropriate temperature, or need to be heated to promote the rate of reaction, but do not cause the decomposition of raw materials or frequent side reactions due to excessive temperature.
In this process, a catalyst may be introduced to reduce the activation energy of the reaction and accelerate the reaction process. And the reaction time must be strictly controlled. If the time is too short, the reaction will not be completed; if the time is too long, too many by-products may be produced.
After the reaction is completed, when the ancient separation and purification methods, such as extraction, distillation, recrystallization, etc., remove unreacted raw materials, by-products and solvents and other impurities, pure 1H - Pyrrole - 3 - carboxamide, 5- (4 - fluorophenyl) - 2 - (1 - methylethyl) - N, 4 - diphenyl - 1 - (2 - (2R, 4R) - tetrahydro - 4 - hydroxy - 6 - oxo - 2H - pyran - 2 - yl) ethyl). Each step requires careful operation to observe the subtle changes in the reaction and fine-tune the reaction conditions according to the actual situation in order to achieve this synthesis.

1H-pyrrole-3-formamide, 5- (4-fluorophenyl) -2- (1-methylethyl) -N, 4-diphenyl-1- (2- (2R, 4R) -tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl) ethyl) This product is common in the market and has different specifications.
However, its specifications often vary according to the use and needs. Or powder, fine particle size, easy to disperse, in some fine chemical synthesis, easy to precise ratio, in order to achieve the desired reaction effect. There are also crystalline ones, with high purity and regular crystal form, which are of great significance in the purity determination and structural analysis of drug research and development.
Its packaging specifications are also rich and diverse. As small as grams, it is suitable for the early stage of scientific research and exploration, with a small amount of samples for research. As large as kilograms or even tons, it is more common in industrial production needs, and large-scale preparation of downstream products. There are those in bottles, which are well sealed and conducive to preservation and access, and prevent moisture and oxidation. There are also those in bags, which are easy to transport and stack, reducing logistics costs.
However, these specifications change with the development of the market and industry. New application scenarios emerge, and specifications may become more diverse to meet the needs of all parties.