1H-Pyrrole-2-carboxylic acid, 4-amino-1-methyl-, methyl ester

This is an investigation into the chemical structure of 1H-pyrrole-2-carboxylic acid, 4-amino-1-methyl-, methyl ester. Its structure can be analyzed by name, "1H-pyrrole-2-carboxylic acid" indicates that it is based on a pyrrole ring, and the carboxyl group is attached to the pyrrole ring at position 2. "4-amino-1-methyl-" shows that there is an amino group at position 4 and a methyl group at position 1. "Methyl ester" epicarboxyl group forms an ester with methanol.
With a pyrrole ring as the core, it has a five-membered heterocycle, contains two double bonds and a nitrogen atom. The nitrogen atom is on the ring, and the pyrrole ring is endowed with special electronic properties and reactivity. The carboxyl group at position 2 (-COOH) is acidic and can form salts, esters and other reactions. The amino group at position 4 (-NH ²) is alkaline and can participate in nucleophilic reactions. The methyl group at position 1 (-CH 🥰) is an alkyl group, which affects the molecular physical and chemical properties.
The methyl ester part, the hydroxyl group in the carboxyl group is replaced by the methoxy group (-OCH 🥰), which is obtained by the esterification reaction of the carboxyl group with methanol. This structure increases the lipophilicity of the molecule and affects the solubility and biological activity.
In summary, the chemical structure of 1H-pyrrole-2-carboxylic acid, 4-amino-1-methyl-, methyl ester is composed of pyrrole ring, amino group, methyl group, and carboxymethyl esterified parts. Each part interacts to give the molecule unique physical and chemical properties and reactivity.

1H-pyrrole-2-carboxylic acid, 4-amino-1-methyl-, methyl ester, this substance has a wide range of uses. In the field of medicine, it may be a key raw material for the creation of new drugs. Due to its unique chemical structure or specific biological activity, it can be combined with specific targets in organisms, and it is expected to develop therapeutic drugs for specific diseases, such as certain intractable diseases, to solve patients' pain.
In the field of materials science, it also has its own uses. With its own chemical properties, it may participate in material synthesis reactions, endowing materials with unique properties, such as improving material stability and enhancing their mechanical properties, so as to promote the birth of new functional materials and promote the development of this field.
In the field of organic synthetic chemistry, this compound is often used as an important intermediate. Due to its structural characteristics, it can react with a variety of reagents through various organic reactions to achieve the construction of complex organic molecules, laying the foundation for the synthesis of more novel and specific functional organic compounds, and expanding the boundaries of organic synthesis.
In addition, in scientific research and exploration, it is used as a research object to help scientists deeply explore basic scientific issues such as relevant chemical reaction mechanisms and molecular interactions, and to enhance human understanding of the chemical world. It provides theoretical support for the long-term development of chemistry.

To prepare 1H-pyrrole-2-carboxylic acid, 4-amino-1-methyl-, methyl ester, you can follow the following ancient method.
First take appropriate starting materials, such as pyrrole derivatives with corresponding substituents. In ancient theory, it is often necessary to choose the reagents and conditions of the reaction carefully. A suitable protecting group can be used to protect a specific position on the pyrrole ring to prevent unnecessary changes in subsequent reactions.
In an appropriate reaction vessel, add this derivative, and add an appropriate amount of solvent, such as alcohol or ether solvent, to create a suitable reaction environment. < Br >
Then, introduce a reagent that can introduce amino groups at 4 positions. This reagent needs to have high reactivity and good selectivity. When reacting, pay close attention to temperature, reaction time and other conditions. If the temperature is too high, it may cause more side reactions; if the time is too short, the reaction will be incomplete.
After the successful introduction of amino groups at 4 positions, proceed with the step of methylation at 1 position. Select an appropriate methylation reagent, and under alkaline environment or specific catalytic conditions, the methyl group can be successfully connected to 1 position.
Finally, the methylation reaction of carboxyl groups is carried out. Methanol and appropriate catalysts, such as concentrated sulfuric acid or p-toluenesulfonic acid, can be selected for heating and refluxing to esterify the carboxyl group with methanol to generate the target product 1H-pyrrole-2-carboxylic acid, 4-amino-1-methyl-methyl-methyl-ester. After the reaction is completed, impurities are removed through separation and purification to obtain a pure product. During the whole process, each step requires fine operation to achieve a good synthesis effect.

4-Amino-1-methyl-1H-pyrrole-2-carboxylic acid methyl ester, which is white to light yellow crystalline powder and is quite stable at room temperature and pressure. Its melting point is about 125-128 ° C, which makes it undergo phase transition in this temperature range when heated.
In terms of solubility, it is slightly soluble in water, but easily soluble in common organic solvents such as methanol, ethanol, and dichloromethane. This difference in solubility is due to the fact that its molecular structure contains both polar groups such as amino and carboxymethyl esters, as well as non-polar parts such as pyrrole rings and methyl groups. Polar groups can form certain interactions with water molecules. However, due to the large proportion of non-polar parts, the whole is only slightly soluble in water; while the molecules of organic solvents are adapted to the forces between the molecules of the substance, so they are more soluble.
Its density is about 1.25 g/cm ³, reflecting the mass distribution of its molecules in unit volume. From the perspective of chemical activity, amino groups have certain alkalinity and can react with acids; carboxyl methyl esters can undergo a series of typical ester reactions such as hydrolysis and alcoholysis, and hydrogen atoms on pyrrole rings can also participate in some substitution reactions. These physicochemical properties are of key significance in the fields of organic synthesis, medicinal chemistry, etc., and are helpful for the preparation and modification of various compounds using them as raw materials.

I don't know the exact price of "1H - Pyrrole - 2 - carboxylic acid, 4 - amino - 1 - methyl -, methyl ester" in the market. This is a fine chemical, and its price often varies depending on quality, purity, supply and demand, purchase quantity and merchant differences.
If you want this product, you can go to the chemical raw material trading platform, such as Gade Chemical Network, Mobell, etc., to check the quotations of different suppliers to know the approximate price range. Or consult chemical reagent companies, such as Sinopharm Group Chemical Reagent Co., Ltd., search banner reagent company, etc. They often give specific quotations according to customer needs and purchase quantity.
In addition, the preparation of this compound may involve special technologies and conditions. If it is used for scientific research, you can first consider whether the existing conditions in the laboratory can meet the requirements for its use, and the procurement should comply with relevant regulations and safety procedures to ensure experimental safety and compliance.
However, due to the lack of exact market data, it is difficult to determine its specific price range. Only through the above channels can relatively accurate price information be obtained.