1h Pyrrole 2 Acetic Acid 1 Methyl 5 4 Methylbenzoyl
pyridine pyrrole pyrazine piperidine piperazine

1H-pyrrole-2-acetic acid, 1-methyl-5-(4-methylbenzoyl)-

    Specifications

    HS Code

    834098

    Chemical Formula C16H15NO3
    Molecular Weight 269.295 g/mol
    Iupac Name 2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetic acid
    Appearance Solid (predicted)
    Boiling Point 533.5°C at 760 mmHg (predicted)
    Melting Point 146 - 148°C
    Density 1.204 g/cm³ (predicted)
    Logp 3.32 (predicted)
    Pka 4.35±0.10 (predicted)
    Solubility Soluble in organic solvents like DMSO, DMF

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    General Information
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    Frequently Asked Questions

    As a leading 1H-pyrrole-2-acetic acid, 1-methyl-5-(4-methylbenzoyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 1H-pyrrole-2-acetic acid, 1-methyl-5- (4-methylbenzoyl) -
    1H-pyrrole-2-acetic acid, 1-methyl-5- (4-methylbenzyl) This substance is an organic compound and the like. Its physical properties are quite complicated, let me tell you one by one.
    Looking at its shape, under normal circumstances, it is mostly in a solid state, or in a crystalline state, delicate and regular, which is due to the orderly arrangement of intermolecular interactions. As for the color, it is often white or off-white, pure and simple, just like unpolished jade.
    Talking about the melting point, it has been determined by many Fangjia experiments that it is about a specific temperature range. This temperature limit is actually the critical point for molecules to break free from the lattice and turn from solid to liquid. The melting point is closely related to the molecular structure, and the strength of the intermolecular forces and the density of the arrangement are all key factors.
    In terms of solubility, it shows different performance in common organic solvents. In some polar organic solvents, such as ethanol and acetone, it has a certain solubility. This is because polar solvents and the molecules of the compound can form interactions such as hydrogen bonds, which help them disperse in the solvent. However, in non-polar solvents, such as n-hexane, the solubility is poor, because the intermolecular forces between the two are difficult to match, like a square chisel, which is incompatible.
    Then talking about density, its density value is also related to the molecular composition and packing mode. Although there is no exact uniform value, it is speculated according to the laws of related similar structural compounds that it is within a certain range. The size of the density depends on its physical behavior such as fluctuation and distribution in a specific environment.
    In addition, the volatility of this substance is weak. Because of its relatively strong intermolecular force, molecules need to overcome a large resistance to break free from the liquid phase and enter the gas phase, so it is not easy to volatilize and can maintain a relatively stable state at room temperature and pressure.
    In summary, the physical properties of 1H-pyrrole-2-acetic acid, 1-methyl-5 - (4-methylbenzyl), are determined by their unique molecular structures, and each property is interrelated to shape its properties in the physical world.
    What are the chemical properties of 1H-pyrrole-2-acetic acid, 1-methyl-5- (4-methylbenzoyl) -
    The chemical properties of 1H-pyrrole-2-acetic acid, 1-methyl-5- (4-methylbenzyl) are as follows:
    This compound is acidic, because it contains a carboxyl group, the hydrogen in the carboxyl group can be partially ionized, and it can neutralize with the base in water to form the corresponding carboxylate and water. For example, in case of sodium hydroxide, the corresponding sodium carboxylate salt and water will be formed.
    It also has nucleophilic substitution reaction activity, because the structure contains nitrogen atoms and aromatic rings. The nitrogen atom has lone pair electrons, which can participate in the reaction as a nucleophilic reagent; the electron cloud density of the aromatic ring is high, and the electrophilic substitution reaction can occur. Under suitable conditions, the hydrogen on the aromatic ring can be replaced by other groups.
    In addition, the compound may participate in the redox reaction. Some groups in its structure will undergo corresponding oxidation or reduction changes under the action of an oxidizing agent or a reducing agent. For example, the benzyl moiety may be oxidized to a carboxyl group or other oxygen-containing group under the action of a specific oxidizing agent.
    At the same time, due to the presence of alkyl groups such as methyl, the compound has a certain hydrophobicity, and its solubility in organic solvents may The pyrrole ring partially has certain stability due to the conjugate structure, but under certain conditions, such as strong acid-base or high temperature, reactions such as ring opening may also occur.
    What is the main use of 1H-pyrrole-2-acetic acid, 1-methyl-5- (4-methylbenzoyl) -?
    1H-pyrrole-2-acetic acid, 1-methyl-5- (4-methylbenzyl) This product is not directly recorded in Tiangong Kaiwu, but its use can be deduced from the perspective of ancient craftsmanship and medicinal knowledge.
    Ancient pharmaceuticals, mostly natural products, were processed and compatible to treat diseases. 1H-pyrrole-2-acetic acid, 1-methyl-5- (4-methylbenzyl) compounds, or exist in some natural herbs. Ancient healers tasted herbs to distinguish their medicinal properties, or occasionally obtained herbs containing this compound, and found that it has certain effects on human diseases. For example, it can regulate qi and blood, and help the human meridians to be unobstructed. In trauma, it can stop bleeding and build muscles, and promote wound healing; in internal diseases, it can reconcile the viscera, relieve diseases such as spleen and stomach discord, qi and blood stasis.
    Furthermore, the ancient printing and dyeing technology is developed. Many plant and mineral raw materials have been extracted and processed to add color to fabrics. The structural characteristics of this compound may make it capable of dyeing or mordant dyeing. Or it can be used as a dye to dye the fabric with a unique color; or it can be used as a mordant to help the dye combine with the fabric more firmly, making the dyeing lasting and bright, uniform in color, and playing a role in the decoration and beautification of the fabric.
    Ancient alchemy was also popular, and alchemists pursued longevity and refined alchemy with goldstone medicine. 1H-pyrrole-2-acetic acid, 1-methyl-5- (4-methyl benzyl) or one of the raw materials for alchemy, although it did not achieve the effect of longevity, the exploration of material properties changes in the alchemy process laid the foundation for the development of later chemistry.
    What is the synthesis method of 1H-pyrrole-2-acetic acid, 1-methyl-5- (4-methylbenzoyl) -
    To prepare 1H-pyrrole-2-acetic acid, 1-methyl-5- (4-methylbenzyl), the method is as follows:
    First take an appropriate amount of starting materials, through clever reaction steps to construct the basic structure. Specific organic reagents can be used to make the raw material molecules react according to the established chemical laws, such as nucleophilic substitution, addition, etc., to initially form the prototype of pyrrole rings.
    In the reaction system, the reaction conditions, such as temperature, pH, reaction time, etc., are precisely regulated. The temperature should be maintained in a moderate range. If it overheats, it may cause side reactions and lead to impure products; if it is too cold, the reaction rate will be slow and take a long time. The pH is also a key factor, and it needs to be adjusted according to the reaction process in a timely manner to facilitate the reaction to advance in the expected direction.
    After the initial construction of the pyrrole ring, the substituents of 2-acetic acid and 1-methyl-5- (4-methylbenzyl) are introduced. The acetic acid group and specific benzyl group can be successfully connected to the target position by a suitable halogenated hydrocarbon under the catalysis of a base.
    During the reaction process, the reaction process needs to be closely monitored, and modern analytical methods, such as thin-layer chromatography, nuclear magnetic resonance, etc., are used to determine whether the reaction has reached the desired stage. After the reaction is completed, the product needs to be separated and purified to obtain high-purity 1H-pyrrole-2-acetic acid, 1-methyl-5- (4-methylbenzyl). Column chromatography, recrystallization and other methods can be used to remove impurities and make the product meet the requirements. In this way, the desired compound can be successfully prepared.
    1H-pyrrole-2-acetic acid, 1-methyl-5- (4-methylbenzoyl) - What is the price range in the market?
    The product you are inquiring about is 1H-pyrrole-2-acetic acid, 1-methyl-5 - (4-methylbenzyl). It is difficult to determine the price of this product in the market. Its price often varies due to many factors, such as the abundance of raw materials, the difficulty of preparation, and the situation of supply and demand.
    If the raw materials are abundant and the preparation method is simple, the price may be slightly lower; on the contrary, if the raw materials are scarce and the preparation is cumbersome, the price will be high. And the state of supply and demand in the market also affects its price. If there are many seekers and there are few suppliers, the price will rise; if the supply exceeds the demand, the price will be depressed.
    As far as I know, this compound is used in the fields of fine chemicals and pharmaceutical research and development. It is used in pharmaceutical research and development, or is a key intermediate, so the demand also fluctuates.
    According to the current market situation, the price of this 1H-pyrrole-2-acetic acid, 1-methyl-5 - (4-methylbenzyl) per gram, or between tens of yuan and hundreds of yuan. However, this is only a rough estimate, not an exact number. The market situation is unpredictable, and if you want to know its exact price, you can only get it by asking chemical raw material suppliers or by looking into recent market transaction data.