1-Benzyl-1H-pyrrole-2,5-dione

1-Benzyl-1H-pyrrole-2,5-dione, an organic compound, has important uses in many fields.
In the field of organic synthesis, it is often used as a key intermediate. Because its structure contains active functional groups, it can undergo a variety of chemical reactions to prepare other types of complex organic molecules. For example, it can use nucleophilic substitution reactions to interact with various nucleophilic reagents to replace hydrogen atoms on benzyl or pyrrole rings, and then form new carbon-carbon bonds or carbon-heteroatomic bonds, which is of great significance in drug synthesis, materials science, etc., and helps to create novel active compounds or functional materials.
In the field of pharmaceutical research and development, the compound may have potential biological activity. Some compounds containing pyrrolidone structure have been studied to show antibacterial, anti-inflammatory, anti-tumor and other pharmacological activities. 1-Benzyl-1H-pyrrole-2,5-dione may be used as a lead compound to develop new drugs with better efficacy and less side effects through structural modification and optimization.
In the field of materials science, it may be used to prepare special polymer materials. By introducing it into the polymer chain, specific properties of the material can be endowed, such as improving the solubility, thermal stability, mechanical properties, etc., so as to meet the requirements of different application scenarios for material properties. With its unique structure and reactivity, 1-benzyl-1H-pyrrole-2,5-dione plays an indispensable role in many fields such as organic synthesis, pharmaceutical research and development, and materials science, and promotes the sustainable development and innovation in various fields.

1-Benzyl-1H-pyrrole-2,5-dione, also known as N-benzylmaleimide. Its physical properties are as follows:
Viewed at room temperature, it is white to light yellow crystalline powder with fine texture.
Smell it, it has a slight special smell, but it is not pungent and unpleasant.
Its melting point is about 81-83 ° C. When heated to this temperature range, it gradually melts from a solid state to a liquid state. This property is crucial in many chemical operations, and can be used to control the reaction process and product morphology.
Its solubility is also an important physical property. In organic solvents, such as ethanol, acetone, chloroform, etc., all have good dissolution performance, which can be evenly dispersed to form a uniform solution; however, in water, the solubility is very small, because of its molecular structure characteristics, the interaction between water molecules is weak, so it is difficult to dissolve in water. This difference in solubility has important applications in the process of separation, purification and preparation, etc., which can be used to select suitable solvents for related operations.
In addition, its density also has a certain value. Although the exact value will vary slightly due to measurement conditions, it is generally within a specific range, which is important for metering and mixing operations in chemical production. It is related to the accuracy of material ratio and reaction effect.

1-Benzyl-1H-pyrrole-2,5-dione, the properties of this substance, according to common sense, should have considerable stability. The reason is that from the perspective of its molecular structure, benzyl and pyrrolidinone structures are connected to each other. In benzyl, the benzene ring has a conjugated system, which can disperse the electron cloud, so that the molecular energy is reduced and stabilized. The cyclic structure of the pyrrolidinone part also gives the molecule a certain rigidity and stability.
Furthermore, from the perspective of chemical health, the chemical bond energy in the molecule is relatively high, and it takes a lot of energy to destroy this structure. Under normal conditions, such as normal temperature and pressure, no special chemical reagents or extreme environmental influences, this compound is not prone to chemical reactions and remains stable in structure.
However, nothing in the world is absolute. If placed under special conditions, such as high temperature environment, the thermal movement of molecules intensifies, and the energy is sufficient to overcome the bond energy of some chemical bonds, or in case of specific strong oxidizing and strong reducing reagents, it can react with some groups in its structure, thereby changing its stability. However, in common experiments and application scenarios, without special treatment, the chemical properties of 1-benzyl-1H-pyrrole-2,5-dione are stable.

Although there is no direct corresponding method for the synthesis of 1-benzyl-1H-pyrrole-2,5-dione in ancient books, it can be deduced according to the principles of related organic synthesis.
The organic synthesis of the past depends on experience and repeated attempts. If you want to synthesize this compound now, you can start from its structure. 1-Benzyl-1H-pyrrole-2,5-dione contains benzyl and pyrrolidinone structures.
First, pyrrole-2,5-dione can be prepared first, and the analogue of pyrrole-2,5-dione can be obtained by reacting maleic anhydride with ammonia or amine compounds. Then, the resulting product is reacted with a benzylating agent, such as benzyl halide, under the catalysis of an appropriate base. The base can help the substrate to form a nucleophilic species, and the nucleophilic attacks the benzyl carbon of the benzyl halide, thereby introducing the benzyl group to obtain 1-benzyl-1H-pyrrole-2,5-dione.
Second, a route can also be designed to introduce the benzyl group into a suitable substrate before constructing the pyrrolidinone structure. For example, the reaction of benzyl-substituted amines with diacid anhydride reagents, through cyclization and other processes, may lead to the formation of its target product. When reacting, it is necessary to pay attention to the control of the reaction conditions, and the temperature, solvent and catalyst are If the temperature is too high, side reactions may increase; the polarity and solubility of the solvent affect the reaction rate and product purity; the choice of catalyst can speed up the reaction process and improve the yield. In this way, with reasonable design and fine operation, 1-benzyl-1H-pyrrole-2,5-dione can be obtained.

1-Benzyl-1H-pyrrole-2,5-dione, in the range of market prices, it is difficult to say for sure. This is due to the complex market conditions, and the change in price is subject to many reasons.
First, the price of raw materials is one of the keys. If the raw materials required for its preparation are easy and affordable, the price of this compound may also become stable and cheap. However, if the raw materials are scarce, the price must be high, resulting in a rise in the price of finished products.
Second, the difficulty of preparation also affects its price. If the synthesis method is cumbersome, requires high-precision techniques and expensive tools, and the yield is not high, the cost will increase greatly and the price will be high. If there is a simple and efficient method, the cost will decrease and the price will also decrease.
Third, the supply and demand of the market is the guidance of the price. If the market is very demanding, but the production is insufficient, the price will rise. On the contrary, if the supply exceeds the demand, the business will be sales, or price reduction promotion.
Fourth, the current situation also has an impact. For example, trade policies and tax regulations can cause price fluctuations.
In the current market, the exact market situation is not known, and it can only be speculated. Or due to the difficulty of preparation and the cost of raw materials, the price fluctuates between tens and hundreds of yuan per gram. However, this is only an idea, and the truth should be subject to real-time inquiry and quotations from various suppliers. To know the exact price, you can visit the platform of the chemical manufacturer and consult the merchants in the industry to get the exact number.