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What is the main use of 1- (4-hydroxyphenyl) -1H-pyrrole-2,5-dione?
1- (4-hydroxyphenyl) -1H-pyrrole-2,5-dione, this substance has a wide range of uses. In the field of medicine, it can be used as a key raw material for the creation of new drugs. Due to its special chemical structure, it can interact delicately with many biomolecules in the body, or can regulate specific physiological processes, helping to fight diseases. For example, when developing drugs targeting specific inflammatory or tumor-related targets, it may play an important role, participating in the combination of drugs and targets through precise molecular docking, and exerting therapeutic effects.
In the field of materials, it also has unique functions. It can be used to prepare functional materials with excellent performance, such as polymer materials with special optical and electrical properties. Introducing it into the structure of polymer can effectively improve the properties of materials, such as enhancing the stability of materials and giving them unique response characteristics. For example, in the creation of smart materials, 1- (4-hydroxyphenyl) -1H-pyrrole-2,5-dione can be used as a responsive group to make the material respond sensitively to specific external stimuli, such as changes in temperature, pH, etc., and then show rich application prospects, such as in sensors, smart coatings, etc.
Furthermore, in the field of organic synthesis chemistry, it is an important intermediate. With its own active functional groups, it can participate in the construction of many complex organic compounds. Chemists can gradually build organic molecules with novel structures and diverse functions through ingenious reaction design, which will contribute to the development of organic synthetic chemistry, promote the field to continuously explore new compound spaces, and expand the boundaries of organic synthesis.
What are the physical properties of 1- (4-hydroxyphenyl) -1H-pyrrole-2,5-dione?
1- (4-hydroxyphenyl) -1H-pyrrole-2,5-dione, this substance has unique physical properties. It is a solid, at room temperature, stable, or powdery in appearance, white and delicate in color, uniform in quality.
When it comes to the melting point, it is about a specific temperature range. This temperature value is the inherent characteristic of the substance, which is very beneficial for identification and purification. When heated to the melting point, it gradually melts from a solid state to a liquid state, and the change of the physical state follows the laws of physics.
Its solubility also has characteristics. In some organic solvents, such as ethanol and acetone, it can exhibit certain solubility properties, which vary depending on the properties of the solvent and temperature differences. In water, the degree of solubility is limited, due to the interaction between molecular structure and water molecules.
In addition, the density of the substance is also a specific value, which is of great significance in the fields of material application, and is related to the distribution and behavior of the substance in the system. Its physical properties such as appearance, melting point, solubility and density together outline the physical appearance of 1- (4-hydroxyphenyl) -1H-pyrrole-2,5-dione, which lays an important foundation for its research and application in many fields such as chemistry and materials.
What is the chemical synthesis method of 1- (4-hydroxyphenyl) -1H-pyrrole-2,5-dione?
To prepare 1- (4-hydroxyphenyl) -1H-pyrrole-2,5-dione, the method is as follows:
Usually 4-hydroxybenzaldehyde and maleic anhydride are used as starting materials. First, 4-hydroxybenzaldehyde and maleic anhydride are mixed in an appropriate solvent, such as pyridine, and catalyzed by an appropriate catalyst, such as a catalytic system composed of acetic anhydride and sodium acetate, heated for azeotropic reflux. During this period, the aldehyde group of 4-hydroxybenzaldehyde undergoes a condensation reaction with maleic anhydride. The anhydride bond of maleic anhydride is opened, and the pyrrole ring is gradually constructed with 4-hydroxybenzaldehyde through a series of processes such as nucleophilic addition After the reaction is completed, the solid precipitates after cooling, and the crude product is filtered.
Compound with a suitable solvent for recrystallization, such as ethanol-water mixed solvent, control the appropriate ratio, heat to dissolve the crude product, and then slowly cool to allow the crystals to precipitate, filter and dry to obtain a relatively pure 1- (4-hydroxyphenyl) -1H-pyrrole-2,5-dione. When operating, pay attention to the control of reaction temperature and time, the choice and dosage of solvent, and the proportion of catalyst are also related to the effect of the reaction. When carefully weighed, the yield and purity can be better.
What is the price range of 1- (4-hydroxyphenyl) -1H-pyrrole-2,5-dione in the market?
I have not heard the exact price of "1- (4 -hydroxyphenyl) -1H - pyrrole - 2,5 - dione" in the market. However, if you want to know the price of this product, you can explore it from various ways.
First, you can visit the cities where chemical raw materials are traded. In this case, there may be a business specializing in such chemicals. Merchants are familiar with the market, and if you ask, you can get an approximate price of the current price. However, the market price often changes from time to time, and the abundance of raw materials and the state of supply and demand can make it move.
Second, ask about the online chemical product trading platform. In today's world, the Internet is convenient, and many platforms list the prices of various chemicals. Search for this item on the platform, or you can get the price marked by different merchants. However, it should be noted that the price of the platform may be different from the actual transaction, and different merchants have different prices due to different quality and quantity.
Third, ask the chemical reagent supplier. They often supply all kinds of chemical reagents, and they may have some preparations for this item. The price may vary depending on the purity and packaging of the reagent. The price of high purity is high or high, and there may be discounts for large packagings.
If you look for the price, you should also know that the price changes constantly. To get an accurate price, you should consult the relevant merchant or platform in person in the near future to know the exact price range in the market.
What are the relevant safety precautions for 1- (4-hydroxyphenyl) -1H-pyrrole-2,5-dione?
1 - (4-hydroxyphenyl) -1H-pyrrole-2,5-dione, this substance involves many safety precautions and needs to be treated with caution.
It is chemically active and should be protected first during operation. When added with appropriate protective equipment, such as chemical-resistant gloves, it can prevent it from making contact with the skin and prevent skin from being invaded and causing allergies and burns; protective glasses are also indispensable, which can prevent it from splashing into the eyes and protect the safety of the eyes. And the operation is suitable for a well-ventilated place. If it is in a closed place, its volatile gas will gather and not disperse, and it will be harmful to health if it enters the body.
Furthermore, its storage is also exquisite. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Due to its active chemical nature, it is dangerous to burn or even explode in case of heat or open flame. At the same time, it should be placed separately from oxidizing agents, reducing agents and other substances to avoid accidents caused by their interaction.
In terms of waste disposal, it must not be discarded at will. It must be properly collected and disposed of in accordance with relevant regulations and standards. Because it may contain harmful ingredients, if it is discarded in nature, seeps into water and soil, pollutes the environment and is harmful to the ecology.
And because of its potential toxicity, it is necessary to strictly control the dose and contact time during experimental research. Researchers should be aware of its nature and hazards, operate according to norms, and record the process and results in detail after the experiment, so as to trace and evaluate the risk. In this way, it can be used to ensure safety.