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What is the chemical structure of 1- [3- [[ (2,5-dioxypyrrolidone) oxy] carbonyl] phenyl] -1H-pyrrole-2,5-dione?
1 - [3- [ (2,5-pyridyl dioxide) oxy] carbonyl] benzyl] -1H-pyridine-2,5-dicarboxylic acid, the structure of this compound is more complex. Its core structure is a pyridine ring, which is connected with carboxyl groups at the 2nd and 5th positions of the pyridine ring, respectively, to form a 2,5-dicarboxylic acid structure.
1 position on the pyridine ring is connected to a structural fragment containing benzyl groups. The benzene ring on the benzyl group is connected to another structure through a carbonyl group. This structure is composed of (2,5-pyridyl dioxide) oxygen groups. The 3rd position of the overall structure is occupied by this complex substituent.
As a whole, it is a multi-substituted pyridine derivative. The introduction of these substituents endows the compound with unique physical and chemical properties. There may be interactions of electronic and spatial effects between different substituents, which affect the stability, reactivity and behavior of the compound in different environments. Various groups in its structure may participate in specific chemical reactions, providing diverse possibilities for research in fields such as organic synthesis and medicinal chemistry.
What are the main uses of 1- [3- [[ (2,5-dioxypyrrolidone) oxy] carbonyl] phenyl] -1H-pyrrole-2,5-dione?
1 - [3 - [[ (2,5 - pyridyl dioxide) oxy] benzyl] pyridyl] -1H - pyridyl - 2,5 - dicarboxylic acid, which has a wide range of uses. In the field of medicine, it can be used as an intermediate in organic synthesis to create a variety of drugs. Some compounds with specific biological activities can be used as starting materials through a series of organic reactions to construct drug molecules with specific structures and functions, which can be used in the treatment and prevention of diseases. In the field of materials science, it can participate in the preparation of functional materials. For example, by complexing with specific metal ions, metal-organic framework materials (MOFs) with unique optical and electrical properties are formed, which are excellent in gas adsorption and separation, catalysis, etc. In the field of catalysis, they may act as ligands, combining with metal catalysts to change the electron cloud density and spatial structure of catalysts, improve the activity, selectivity and stability of catalysts, and thus promote the efficient progress of various chemical reactions, such as carbon-carbon bond formation reactions and oxidation reactions. In addition, in the field of agricultural chemistry, some compounds developed on this basis may have positive effects on crop growth regulation and pest control, contributing to the sustainable development of agriculture.
What is the synthesis method of 1- [3- [[ (2,5-dioxypyrrolidinyl) oxy] carbonyl] phenyl] -1H-pyrrole-2,5-dione?
The synthesis of 1 - [3 - [ (2,5 -pyridyl dioxide) oxy] aldehyde] benzyl] -1H -pyridine-2,5 -dicarboxylic acid is a key topic in the field of organic synthetic chemistry. Although the specific synthesis method is not described in Tiangong Kaizi, according to the conventional ideas and traditional chemical wisdom of today's organic synthesis, it may be discussed according to the following ancient ideas.
To synthesize this substance, the selection of starting materials is crucial. Or pyridine derivatives can be selected as the basic raw materials, because their structure is partially compatible with the target product pyridine ring. First, the 2,5-position of the pyridine ring is modified. Pyridine can be introduced into the halogen atom at the 2,5-position by a halogenation reaction, such as bromine with a suitable catalyst, such as iron powder, and pyridine under heating conditions to bromide at the 2,5-position to obtain 2,5-dibromopyridine.
Subsequently, 2,5-dibromopyridine is reacted with an oxygen-containing reagent. For example, by reacting with a sodium alcohol reagent, nucleophilic substitution, the oxygen group is introduced at the 2,5-position to obtain a 2,5-pyridine dioxide derivative. On the basis of this derivative, the aldehyde group is attached to the pyridine ring. The derivatives can be treated by a Vilsmeier-Haack reaction with a mixture of N, N-dimethylformamide (DMF) and phosphorus oxychloride (POCl
As for the introduction of the benzyl part, the aldehyde-containing pyridine derivative can be reacted with benzyl halide, such as benzyl bromide, under basic conditions by Williamson ether synthesis. The base can be selected from potassium carbonate, etc., heated and refluxed in a suitable organic solvent such as acetone, so that the two are connected to obtain a benzyl-containing pyridine derivative.
Finally, the carboxylation reaction is carried out for the 2,5-position of the pyridine ring. The above derivatives can be reacted with carbon dioxide at low temperature in anhydrous ether and other solvents through Grignard reagent intermediates, and finally carboxylated to produce the target product 1 - [3- [ (2,5-pyridyl dioxide) oxy] aldehyde] benzyl] -1H-pyridine-2,5-dicarboxylic acid. Each step of the reaction requires precise control of the reaction conditions, including temperature, time, reagent dosage, etc., to achieve the ideal yield and purity.
What are the physical properties of 1- [3- [[ (2,5-dioxypyrrolidone) oxy] carbonyl] phenyl] -1H-pyrrole-2,5-dione?
1 - [3 - [[ (2,5 -pyridyl dioxide) oxy] carbonyl] benzyl] -1H -pyridine-2,5 -dione, which is an organic compound. Its physical properties are as follows:
Looking at its properties, it is mostly solid under normal conditions, but the specific form may vary depending on the purity and preparation conditions.
When it comes to melting point, there is no exact universal value. Due to differences in different literature reports or experimental conditions, the melting point data will fluctuate. But generally speaking, within a certain temperature range, when heated to this temperature range, the substance gradually melts from a solid state to a liquid state. The boiling point of
also varies depending on the experimental measurement conditions. However, usually at higher temperatures, it will change from liquid to gaseous state, and the temperature required for this process is the boiling point.
In terms of solubility, in organic solvents, such as common ethanol and dichloromethane, it has a certain solubility. This characteristic is due to the specific interaction between its molecular structure and the molecules of the organic solvent, so that the molecules can be uniformly dispersed in the solvent. However, in water, the solubility is poor, because the polarity of the molecule and the polarity of the water molecule are not well matched, and it is difficult for the water molecule to effectively disperse and surround the substance molecules. < Br >
In terms of density, although the exact value needs to be determined by specific experimental instruments, it can be inferred that it is similar to the density of common organic compounds, which is closely related to the type, number and spatial arrangement of atoms constituting the substance.
The physical properties of this substance are of great significance in chemical synthesis, separation and purification, and related chemical reactions, providing a key reference for many studies and applications in the field of organic chemistry.
What is the market outlook for 1- [3- [[ (2,5-dioxypyrrolidone) oxy] carbonyl] phenyl] -1H-pyrrole-2,5-dione?
1 - [3 - [[ (2,5 -pyridyl dioxide) oxy] benzyl] pyridyl] -1H -pyridine-2,5 -dione, which is an organic compound with a specific structure. As for its market prospects, it can be viewed from the following numbers:
First, in the field of pharmaceutical research and development, such compounds containing nitrogen heterocycles and special substituents may exhibit unique biological activities. Pyridine rings are key structural units in many drug molecules and can participate in the interaction with biological macromolecules. If this compound can be confirmed by research to have affinity and inhibitory or activating effects on specific disease targets, such as inhibition of specific protein kinases in some tumor cells, or regulation of neurotransmitter receptors, it will arouse strong interest from pharmaceutical companies and scientific research institutions, and the market prospect is broad.
Second, in the field of materials science, compounds containing pyridine structures may be used to prepare functional materials. For example, they may be used as ligands to coordinate with metal ions to construct metal-organic framework materials (MOFs) with specific optical and electrical properties for gas adsorption, separation or luminescent materials. If high-performance materials based on this compound can be developed, new market applications will be opened up.
Third, in agricultural chemistry, pyridine compounds often have bactericidal and insecticidal activities. If this 1- [3- [[ (2,5-pyridyl dioxide) oxy] benzyl] pyridyl] -1H-pyridine-2,5-dione has been tested to have a good control effect on common crop diseases and insect pests, and is environmentally friendly and low toxicity, it is expected to become a new type of pesticide active ingredient and occupy a certain market share of agricultural chemicals.
However, its market prospects are also restricted by many factors. If the cost of synthesis is too high, it will limit its large-scale production and application; furthermore, if the biosafety and environmental impact are poorly assessed, it will be difficult to gain market acceptance. Therefore, if the above potential problems can be effectively solved, the market prospect of this compound is promising.