1-(2-Furfuryl)pyrrole

(1 - (2 - amino) pyridine is mainly used as an intermediate for the synthesis of organic compounds such as pharmaceuticals, pesticides and dyes. In the field of medicine, it is a key starting material for the synthesis of many drugs, such as some antibacterial and anti-inflammatory drugs with specific biological activities. By modifying and derivatizing the structure of (1 - (2 - amino) pyridine, molecular structures with precise pharmacological effects can be constructed, providing effective means for disease treatment. In the field of pesticides, it can be used as an important intermediate for the synthesis of high-efficiency and low-toxicity pesticides. With the special electronic structure and amino reaction activity of the pyridine ring, pesticide products targeting specific pests or diseases can be created, contributing to the control of pests and diseases in agricultural production. In the field of dyes, (1 - (2 - amino) pyridine can participate in the construction of dye molecules, endowing dyes with excellent photostability, color brightness and other properties, and is widely used in textile, printing and dyeing industries to meet people's demand for rich and lasting colors.)

The physical properties of (1- (2-amino) pyridine are various. It is an organic compound with specific physical and chemical properties.
In terms of physical properties, 2-aminopyridine is a white to light yellow crystalline powder under normal conditions, stable at room temperature. Its melting point is between 58 and 62 degrees Celsius, which makes it have a phase transition in a specific temperature range. The boiling point is about 272-273 degrees Celsius, indicating that it boils and gasifies at a higher temperature. It has a certain solubility in water and can be soluble in organic solvents such as ethanol and ether. This solubility is conducive to its participation in reactions or separation and purification operations in different solvent systems.
From the perspective of chemical properties, 2-aminopyridine has a certain alkalinity due to the existence of amino groups. There are lone pairs of electrons on the nitrogen atom of the amino group, which can react with acids to form corresponding salts. At the same time, the conjugate structure of the pyridine ring endows it with certain stability, and the electron cloud distribution characteristics on the ring determine that it can undergo electrophilic substitution reactions. Under appropriate conditions, amino groups can be further modified, such as acylation and alkylation, resulting in the derivation of a variety of compounds. These reaction characteristics make it widely used in the field of organic synthesis and can be used to prepare intermediates for many fine chemicals such as medicine, pesticides, and dyes.)

(Is the chemical property of 1- (2-amino) pyridine stable?)
(To know this question, its structural characteristics should be known. 1 - (2-amino) pyridine, its amino group is connected to the pyridine ring. Pyridine ring is aromatic, and the electron cloud distribution has its own characteristics. Amino is a power supply group, which can affect the electron cloud density and reactivity of the pyridine ring.)
(From the perspective of electrophilic substitution reaction, the electron cloud density of the adjacent and para-position of the pyridine ring can be relatively increased by the electron supply effect of the amino group, and the electrophilic substitution in the adjacent and para-position is more likely to occur. However, the electron cloud density of the pyridine ring itself is lower than that of the benzene ring, and the electrophilic substitution activity is weaker than that of the benzene ring. This structural property makes 1- (2-amino) pyridine have its unique reaction check point and activity during the electrophilic substitution reaction.)
(In terms of stability, from the perspective of bond energy, the carbon-carbon bond, carbon-nitrogen bond of the pyridine ring and the bond between the amino group and the pyridine ring all have certain bonds to maintain the structure. Under normal conditions, if there are no extreme conditions such as strong oxidizing agents, strong acids and strong bases, the molecular structure can be maintained relatively stable.) < Br >
(However, in some special environments, such as high temperature, strong acid-base, and strong redox systems, the chemical properties of 1- (2-amino) pyridine may change. Strong oxidizing agents may cause amino oxidation, or open the pyridine ring; strong acids and bases may protonate or react with amino groups or other acids and bases, affecting the stability of their chemical properties.)
(In general, under normal mild conditions, the chemical properties of 1- (2-amino) pyridine are relatively stable; however, in extreme special environments, its stability may be destroyed.)

To prepare 1 - (2 - amino) pyridine, there are many ways to synthesize it. The common ones are as follows:
First, pyridine is used as the starting material, nitropyridine is obtained by nitrification, and then the nitro group is reduced to an amino group. This process can be achieved through several steps of reaction with the help of suitable reducing agents, such as iron and hydrochloric acid systems. The general steps of the reaction are: first, pyridine is reacted with nitrifying reagents under specific conditions to introduce nitro; then, the nitro group is converted into an amino group by reduction means to obtain the target product 1 - (2 - amino) pyridine. The raw material pyridine is relatively easy to obtain in this way, but the reaction steps are slightly more, and the reaction conditions of each step need to be carefully controlled to improve the yield and purity.
Second, a nitrogen-containing heterocyclic compound is reacted with a suitable amination reagent. For example, a specific nitrogen-containing heterocyclic ring is selected and reacted with an amination reagent under appropriate catalyst and reaction conditions, and 1- (2-amino) pyridine is generated through cyclization, rearrangement and other processes. This method requires precise selection of nitrogen-containing heterocyclic raw materials and amination reagents, which requires strict reaction conditions, but if the conditions are suitable, the target product can be obtained efficiently.
Third, coupling reaction catalyzed by transition metals. Appropriate halogenated pyridine derivatives and amine compounds are selected to realize the coupling of carbon-nitrogen bonds under the action of transition metal catalysts such as palladium catalysts, and then 1- (2-amino) pyridine is synthesized. This method has high reactivity and good selectivity, but the cost of transition metal catalysts is higher, and the post-reaction treatment may require fine operation to remove catalyst residues, so as not to affect the quality of the product.
Each synthesis method has its advantages and disadvantages. In practical application, it is necessary to comprehensively consider many factors such as raw material availability, cost, yield and product quality requirements, and carefully select the optimal synthesis path to efficiently prepare 1- (2-amino) pyridine.

In today's market, the price of (2-amino) pyridine has changed due to various reasons. The amount of its production, the amount of demand, and the ups and downs of various materials, labor costs, and the market can all affect its price.
Basically speaking, its pure quality is high and the quantity is widely available in the market, and the price per gram may be between a few yuan and a few tens of yuan. If it is a crude product, the impurities are slightly more, and the price is slightly cheaper, or a few corners per gram to a few yuan. However, this large number is actually in the market, and the price often varies from time to place.
And sold by various merchants in the market, the price varies depending on the brand, purity, and packaging. There are merchants who are of high quality, and the products they sell are pure and fine. Although the price is high, there are many people who seek it. There are also merchants who win by quantity, and the price is slightly flat, which is suitable for those who do not have the extreme requirements for purity.
Therefore, if you want to know the exact price, you should consult the merchants in the cities in person, or on the e-commerce platform, carefully check the price marked by each store, and compare it. Only then can you get a summary of the price of (2-amino) pyridine in the market.