1 2 Chlorophenyl 1h Pyrrole 2 Carbaldehyde
pyridine pyrrole pyrazine piperidine piperazine

1-(2-chlorophenyl)-1H-pyrrole-2-carbaldehyde

    Specifications

    HS Code

    933440

    Chemical Formula C11H8ClNO
    Molar Mass 205.64 g/mol
    Appearance Solid (usually a powder or crystalline solid)
    Physical State At Room Temperature Solid
    Odor Typically has a characteristic organic odor
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Melting Point Varies, but typically in a certain temperature range
    Boiling Point Relatively high boiling point due to molecular structure
    Density Specific density value based on experimental determination
    Flash Point Indicative of flammability risk in presence of ignition source

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    General Information
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    Frequently Asked Questions

    As a leading 1-(2-chlorophenyl)-1H-pyrrole-2-carbaldehyde supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 1- (2-chlorophenyl) -1H-pyrrole-2-formaldehyde?
    1 - (2 - cyanoethyl) - 1H - imidazole - 2 - ethyl acetate, this substance is colorless to pale yellow transparent liquid. Looking at its shape, it flows like water, and it can be seen that it is clear and bright under light. Its boiling point is quite high, about a certain temperature range, at this temperature, it liquefies into gas, rises and dissipates. The melting point is also fixed, and at a certain low temperature limit, the liquid gradually condenses into a solid state. Its density is moderate, placed in a container, and compared with the common substance of the same volume, it is light and heavy.
    Solubility is one of its important characteristics. It can be soluble in some organic solvents, such as alcohols and ethers. It is like salt dissolving in water and dispersing evenly to form a uniform and stable state; but it is difficult to dissolve in water. The two meet, like oil and water, distinct and living in one place.
    1- (2-cyanoethyl) -1H-imidazole-2-ethyl acetate has good stability. It can maintain its own structure and properties for a long time at room temperature and pressure, and does not easily change with surrounding substances. When encountering specific conditions, such as high temperature, strong acid and alkali environment, structure or change, chemical reactions are induced. This feature requires careful consideration when storing and using it, and a suitable environment should be selected to ensure its quality.
    What are the chemical synthesis methods of 1- (2-chlorophenyl) -1H-pyrrole-2-formaldehyde?
    The chemical synthesis method of 1- (2-cyanobenzyl) -1H-pyrrole-2-acetic acid is related to the field of organic synthesis, which is the key to the preparation of such compounds. The following detailed synthesis paths:
    First, pyrrole is used as the starting material. Pyrrole has a unique electronic structure and can undergo nucleophilic substitution reaction with halogenated hydrocarbons containing cyanobenzyl groups under appropriate conditions. Under the catalytic action of a base, the lone pair electron of the pyrrole nitrogen atom attacks the carbon atom of the halogenated hydrocarbon, and the halogen ion leaves, resulting in 1- (2-cyanobenzyl) -1H-pyrrole. Subsequently, after hydrolysis, the cyanyl group is converted into a carboxyl group to obtain the target product 1- (2-cyanobenzyl) -1H-pyrrole-2-acetic acid. This pathway step is clear, but the nucleophilic substitution reaction needs to select the appropriate base and reaction conditions to ensure the smooth progress of the reaction, and the control of the hydrolysis reaction is also crucial to prevent overreaction or side reactions.
    Second, the pyrrole ring can also be constructed first. For example, pyrrole derivatives are synthesized by cyclization with appropriate nitrogen-containing and carbon-containing compounds, and cyanobenzyl groups are introduced at specific positions in the pyrrole ring. This purpose can be achieved by reactions such as condensation reaction and cyclization addition. Subsequent to the conversion of functional groups, the related groups are converted into carboxyl groups to obtain the target product. This path is highly flexible, but the reaction steps may be complicated, and the reaction route needs to be carefully designed to improve the yield and purity of the target product.
    Third, the coupling reaction catalyzed by transition metals. Using pyrrole derivatives containing halogen atoms and cyanobenzylboronic acid or its ester compounds as raw materials, under the action of transition metal catalysts such as palladium catalysts, a coupling reaction occurs to form a carbon-carbon bond to construct a 1- (2-cyanobenzyl) -1H-pyrrole structure. Then carboxylation reactions introduce carboxyl groups. This method has high selectivity and can effectively construct specific structures, but the cost of transition metal catalysts is high, and the reaction conditions are relatively harsh, requiring strict anhydrous and anaerobic operation of the reaction system.
    What fields are 1- (2-chlorophenyl) -1H-pyrrole-2-formaldehyde used in?
    1- (2-Cyanobenzyl) -1H-pyrrole-2-acetic acid, which is used in the fields of medicine, pesticides, and materials. The details are as follows:
    ###Pharmaceutical field
    1. ** Anti-tumor drug development **: Its unique structure can be used as a key intermediate to participate in the synthesis of a variety of anti-tumor active substances. For example, some new targeted anti-cancer drugs, through reasonable modification of the compound structure, can enhance the affinity and inhibitory activity of specific targets of tumor cells, and inhibit tumor growth by interfering with tumor cell proliferation and metastasis-related signaling pathways.
    2. ** Neurological drugs **: Potential interactions with neurotransmitter receptors. By modifying its chemical structure, drugs can be developed for the treatment of neurological diseases, such as Parkinson's disease, Alzheimer's disease, etc. By modulating neurotransmitter transmission, improve the function of the nervous system.
    ###Pesticide field
    1. ** Insecticide **: It has certain insecticidal activity, and can improve the toxic effect on specific pests by modifying its structure, while reducing the toxicity to non-target organisms. The mechanism of action may interfere with the normal physiological function of the nervous system and respiratory system of pests, causing pest death.
    2. ** Fungicide **: It can inhibit the growth and reproduction of certain plant pathogens to protect crops from disease attacks. Or achieve sterilization by destroying the cell wall and cell membrane synthesis of pathogenic bacteria and interfering with its metabolic process.
    ###Material Field
    1. ** Organic Synthetic Materials **: As an organic synthetic block, it can participate in the construction of polymer materials with special properties. By polymerizing with other monomers, the material is endowed with unique electrical, optical and thermal properties, which are used in the manufacture of electronic devices and optical materials.
    2. ** Functional Coating Materials **: After appropriate chemical modification, it can be used to prepare functional coatings. The coating may have good anti-corrosion, wear resistance and self-cleaning properties, and is widely used in surface protection of metal materials and building materials.
    What are the market prospects for 1- (2-chlorophenyl) -1H-pyrrole-2-formaldehyde?
    Methyl 1- (2-cyanobenzyl) -1H-indole-2-acetate is an organic compound in the field of pharmaceutical and chemical industry. Looking at its market prospects, there are the following numbers:
    In the field of pharmaceutical research and development, it has high potential value. Many studies have shown that compounds containing indole structures often exhibit various biological activities, such as anti-tumor, anti-inflammatory, and antibacterial. Methyl 1- (2-cyanobenzyl) -1H-indole-2-acetate may be modified by indole ring to obtain lead compounds with specific pharmacological activities, which have been further developed into new drugs. At present, the demand for the treatment of major diseases such as cancer is urgent, and the market for anti-tumor drugs continues to expand. If new drugs are developed based on this compound, it is expected to gain a share of the market.
    In the field of chemical synthesis, it can be used as a key intermediate. Organic synthesis often requires a variety of intermediates to construct complex molecular structures. Its unique structure contains indole ring, cyanobenzyl, methyl acetate and other functional groups, which can react with other compounds through various chemical reactions, such as nucleophilic substitution, addition, etc., to prepare more complex and specific organic materials or fine chemicals. With the upgrading of the chemical industry, the demand for high value-added fine chemicals is increasing. As an intermediate, this compound may welcome a broad application space.
    However, its market also has challenges. The synthesis of this compound may require specific reaction conditions and raw materials, and the complexity and cost of the synthesis process may limit large-scale production and application. And new compounds require long R & D cycles and high costs in marketing activities, and must pass strict safety and efficacy evaluations. But in general, with the advancement of science and technology and in-depth research, if the synthesis problem can be overcome and the cost can be reduced, 1- (2-cyanobenzyl) -1H-indole-2-acetate methyl ester may bloom in the fields of medicine and chemical industry, the market prospect is promising.
    What are the safety and toxicity of 1- (2-chlorophenyl) -1H-pyrrole-2-formaldehyde?
    1 - (2 - cyanobenzyl) - 1H - pyrrole - 2 - ethyl acetate, this substance is related to safety and toxicity, and should not be ignored.
    Its safety is quite complex, under specific environments and conditions, it may show a certain stability, but in case of high temperature, open flame, strong oxidant, etc., it will be like an abyss, which is very likely to cause danger. High temperature can cause its chemical bonds to be turbulent, or cause substances to decompose, generating irritating or even toxic gases, such as irritating and even toxic gases. In a confined space, it is more likely to cause the risk of explosion, just as dry wood is ready to explode when exposed to fire.
    When it comes to toxicity, after many studies and practice observations, it may be potentially harmful to organisms. If accidentally exposed to the skin, some people may experience allergic symptoms, skin itching, redness and swelling, as if a delicate flower has been eaten by insects. If ingested orally, or launched a violent attack on the digestive system, it can cause nausea, vomiting, abdominal pain and other symptoms, just like an internal storm raging. Long-term or large-scale exposure can even involve key organs such as the nervous system, liver, and kidneys, and interfere with normal physiological functions, such as damage to precision clock parts and malfunction.
    In addition, for the ecological environment, if it flows into nature, or accumulates in water bodies and soil, it will be toxic to aquatic organisms, soil microorganisms and other ecological chain bottom links, and then affect the balance and stability of the entire ecosystem like dominoes. Therefore, in all aspects related to the production, transportation, storage and use of this object, it is necessary to strictly follow safety regulations and take comprehensive protective measures, such as wearing armor, to protect people and maintain ecological integrity.