tert-Butyl2-amino-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

This is the name of an organic compound, and its chemical structure is very complex. According to the naming rules of organic chemistry, "tert-Butyl", tert-butyl is also a branched alkyl group containing four carbon atoms, connected to the main structure by tert-carbon atoms. "2-amino-6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylate" part, revealing that the main structure is composed of thiazolo-pyridine rings.
"2-amino" shows that the amino group is attached to the second position of the ring; "6,7-dihydro" shows the double bond hydrogenation of the 6,7 positions; "5 (4H) " refers to the 5-position carbon in the 4H configuration; "carboxylate" shows the carboxylate group. Overall, the structure of this compound is that tert-butyl is attached to the carboxylate group of 2-amino-6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylic acid ester to form a complete organic molecular structure. In this structure, the thiazolopyridine ring system is the core, and the amino group, dihydrogen structure and ester group give it unique chemical properties and reactivity.

Tert-butyl 2-amino-6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylic acid ester, this is an organic compound. Its main physical properties are as follows:
Looking at its appearance, it may be white to off-white crystalline powder under normal circumstances, with fine texture, like snow falling in the early winter, pure and delicate, placed in light, or shimmering with a faint luster, like a fine star hidden among the powders.
Talking about the melting point, due to the specific stability of the compound structure, its melting point is in a relatively high range, about 150-160 ° C. When the temperature gradually rises near the melting point, the compound seems to wake up from a slumber, the lattice structure gradually disintegrates, and slowly melts from the solid state to the liquid state, just like ice and snow meet the warm sun, quietly melting.
In terms of solubility, it exhibits good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide, such as water, which can be evenly dispersed to form a clear and transparent solution. However, in water, the solubility is not good, because the hydrophobic groups in the molecular structure account for a large proportion, and water molecules are difficult to associate with it. It is like the incompatibility of oil and water, so it mostly exists in the form of suspension or precipitation in water.
The density of this compound is about 1.3 to 1.4 g/cm ³. Compared with common organic solvents, the density is slightly higher. If it is placed in a suitable container and co-placed with other liquids of different densities, it can be seen that it is stratified according to the density difference, just like different classes in the world.
In addition, the compound may have certain hygroscopicity. In a high humidity environment, it is like a sponge absorbing water, slowly absorbing moisture in the air, causing its own weight to increase, and its appearance may also change. The dry powder gradually becomes moist. Therefore, it is necessary to pay attention to moisture-proof when storing, such as in a dryer, to ensure its stable quality.

Tert-butyl 2-amino-6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylate is commonly used in many reactions in organic synthesis.
It can be used as a key building block in the reaction of constructing nitrogen-containing heterocycles. The structure of Gainthiazolopyridine is rich in nitrogen atoms and sulfur atoms, and has unique electronic properties and spatial structures, which is of great significance in the field of heterocyclic synthesis. For example, in the nucleophilic substitution reaction, the amino and carboxyl groups of tert-butyl 2-amino-6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylic acid esters can be used as nucleophilic check points to react with electrophilic reagents such as halogenated hydrocarbons and acyl halides, thereby expanding the molecular skeleton and laying the foundation for the construction of more complex nitrogen-containing heterocyclic compounds.
In the lead compound optimization process of pharmaceutical chemistry, this compound is also a commonly used intermediate. Because of its heterocyclic structure, it can form a variety of non-covalent interactions with biological targets, such as hydrogen bonds 、π - π stacking, etc., thereby imparting biological activity to the compound. Chemists often modify the substituents of tert-butyl 2-amino-6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylic acid esters to adjust the physicochemical properties and biological activities of compounds, and then search for highly active and highly selective lead compounds.
In some condensation reactions, the carboxyl group of the compound can be condensed with alcohols, amines, etc., to form ester or amide bonds, introduce different functional groups, and change molecular polarity and spatial conformation, which is essential for the design and synthesis of compounds with specific biological activities or physical properties. In conclusion, tert-butyl 2-amino-6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylic acid esters are widely used and play a key role in the field of organic synthesis and drug discovery.

The method of biosynthesis of tert-Butyl 2-amino-6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylate covers several ends.
First, it can be started from a suitable pyridine derivative. First, a sulfur-containing group is introduced at a specific position on the pyridine ring, or through a nucleophilic substitution reaction, a sulfur-containing nucleophilic reagent interacts with a pyridine halogen. This halogen needs to have a good leaving group at a specific position. Then, the sulfur atom is cyclized with the adjacent carbon atom to construct a thiazole ring, or the intramolecular cyclization reaction occurs by heating and adding a specific catalyst.
Second, it can also be started from thiazole derivatives. If the thiazole ring already has a partial structure, the pyridine ring can be constructed. For example, through a suitable carbon-nitrogen bond formation reaction, the nitrogen-containing fragment is connected to the thiazole ring to build the pyridine part. In this process, a metal-catalyzed coupling reaction, such as a palladium-catalyzed amination reaction, may be used to precisely form the required carbon-nitrogen bond.
Furthermore, the selection of starting materials and the optimization of reaction conditions are crucial. The reaction solvent needs to be selected according to the characteristics of each step of the reaction, and the polar or non-polar solvent has an impact on the reaction process and yield. Temperature is also a key factor. Reactions at different stages may require low temperature to control selectivity, or high temperature to promote reaction rate. The screening of catalysts cannot be ignored. The activity and selectivity of different catalysts vary greatly. Careful selection should be made to achieve high efficiency and accuracy in synthesis.
Synthesis of tert-Butyl 2-amino-6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylate requires careful consideration of factors such as raw materials, reaction steps, solvents, temperatures and catalysts, and careful planning to succeed.

Alas! This tert - Butyl 2 - amino - 6,7 - dihydrothiazolo [5,4 - c] pyridine - 5 (4H) -carboxylate is also one of the organic compounds. It may be of great use in the field of pharmaceutical research and development. In the way of creating medicine, it is often necessary to explore compounds with specific structures in order to find the possibility of new drugs. The unique structure of this compound may make it have the potential to bind specifically to biological targets, so it may emerge in the field of disease treatment, such as anti-cancer and anti-virus.
In the field of pesticide development, it should not be underestimated. Today's agriculture requires high-efficiency, low-toxicity and environmentally friendly pesticides. The characteristics of this compound may make it modified and transformed into the cornerstone of a new type of pesticide, protecting farmers from the invasion of pests and diseases, and reducing its harm to the environment.
Furthermore, in the field of material science, there may be opportunities for application. The innovation of materials is related to the development of many industries. If this compound can be combined with specific materials to improve the properties of materials, such as improving their stability and conductivity, it may be used in electronics, aviation and other industries.
However, this is all speculation, and its real market application field still needs to be repeatedly tested and explored by researchers before they can get a conclusive theory.