TERT-BUTYL 6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDINE-5(4H)-CARBOXYLATE

The chemical structure of "tert-butyl 6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylate" is an important topic in the field of organic chemistry. This compound is composed of tert-butyl, dihydrothiazolo-pyridine ring and formate group.
Looking at its structure, tert-butyl is a branched alkyl group containing three methyl groups. It is connected to a specific position and has a great influence on the spatial configuration and physicochemical properties of the compound. Its steric resistance effect is significant, which can affect the reactivity and stability of the molecule.
Dihydrothiazolo [5,4-c] pyridine ring fuses thiazole ring and pyridine ring to form a unique fused ring structure. The thiazole ring contains sulfur and nitrogen heteroatoms, and the pyridine ring also contains nitrogen atoms, endowing the ring with rich electronic properties and reactive activity check points. The double bond and single bond in the ring are alternately arranged to form a conjugated system, which enhances the stability of the molecule and affects its optical and electrical properties.
5 (4H) -formate ester group, connected to a specific position in the ring, is an ester functional group. Its chemical properties are active, prone to hydrolysis, alcoholysis and other reactions, and it is often used as a reaction intermediate in organic synthesis to introduce specific functional groups or construct complex molecular structures.
The overall structure of this compound makes it have a variety of chemical properties and potential application value, and may have important uses in medicinal chemistry, materials science and other fields. In medicinal chemistry, or because of its special structure and activity check point, it exhibits specific biological activity and can be used as a lead compound for drug research and development; in materials science, its unique electronic and physical properties may make it suitable for the preparation of new functional materials.

Tert-butyl 6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylic acid ester, which has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to help create new drugs. The structure of Geiinthiazolopyridine has unique biological activities and can closely bind to specific targets in the body, just like a delicate key to fit a precise lock, or regulate physiological processes, or intervene in disease progression, so it is often relied on when developing antibacterial, anti-inflammatory, anti-tumor and other drugs.
In the world of organic synthesis, tert-butyl 6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylate also plays an important role. With its specific structure and reactivity, it can participate in many organic reactions, such as nucleophilic substitution, cyclization, etc. It is like a cornerstone of a complex building, providing the possibility for the synthesis of various organic compounds with novel structures and unique functions, greatly enriching the types and properties of organic compounds.
Furthermore, in the field of materials science, with appropriate chemical modification, this compound may endow the material with special optical, electrical or mechanical properties, illuminating the light of hope for the development of new functional materials, and is expected to emerge in the fields of electronic devices, optical materials, etc., and contribute to the progress of related industries. In short, tert-butyl 6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylate plays an important role in many fields due to its unique structure and diverse reactivity, and has broad prospects.

To prepare tert-butyl 6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylic acid ester, the following ancient method can be used.
First take an appropriate amount of 6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylic acid and place it in a clean reaction vessel. This carboxylic acid needs to be carefully purified to ensure that there are few impurities, so as not to disturb the subsequent reaction.
Take an appropriate amount of tert-butyl alcohol and slowly add it to the above-mentioned container containing carboxylic acid. The amount of tert-butyl alcohol should be accurately prepared according to the stoichiometric ratio, and there should be no difference. < Br >
Then, add an appropriate amount of dehydrating agent, such as concentrated sulfuric acid or dicyclohexyl carbodiimide (DCC), etc. The function of the dehydrating agent is to accelerate the esterification reaction between carboxylic acid and tert-butanol, remove the water generated by the reaction, and move the reaction equilibrium in the direction of ester formation.
During the reaction, the temperature and reaction time need to be controlled. The reaction vessel can be placed in a constant temperature water bath or an oil bath to maintain a suitable temperature. If the temperature is too high, side reactions may occur; if the temperature is too low, the reaction will be delayed. According to general experience, the reaction temperature is usually controlled in a moderate range, such as tens of degrees Celsius, and the reaction is continuously stirred to allow the reactants to be fully mixed and contacted.
After the reaction is completed, the product needs to be separated and purified. The organic phase containing the product can be extracted with an organic solvent first. Then distillation, recrystallization and other means are carried out to remove unreacted raw materials, by-products and impurities to obtain pure tert-butyl 6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylate. The whole process requires careful operation by the experimenter and micro-knowledge to obtain satisfactory results.

Tert-butyl 6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylic acid ester is one of the organic compounds. Its physical properties are unique, let me tell them one by one.
First of all, its appearance is usually a white to off-white solid powder with fine texture and purity in appearance. This form is easy to store and use, and it is easy to operate in many chemical reactions.
The melting point is determined by experiments, and its melting point is within a specific range. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. This property is crucial in the identification and separation and purification of compounds. If the purity of the substance is high, the melting point is sharp and the fluctuation range is small; conversely, if there are many impurities, the melting point decreases and the melting range becomes wider.
Furthermore, its solubility is also a key property. In organic solvents such as dichloromethane, N, N-dimethylformamide, tert-butyl 6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylate exhibits good solubility. Organic solvents provide a medium for chemical reactions, and good solubility allows the reactants to fully contact, accelerate the reaction process, and improve the reaction efficiency. However, in water, its solubility is poor. Due to the molecular structure of the compound, the force between it and water molecules is weak, making it difficult to form a stable dispersion system.
In addition, tert-butyl 6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylic acid ester has certain stability. Under normal storage conditions, in a dry and cool place, it can maintain the stability of its chemical structure and physical properties, and is not easy to decompose or deteriorate. In case of extreme conditions such as strong acid, strong base or high temperature, its structure may be affected, triggering chemical reactions and causing changes in properties.

Alas! I am now inquiring about the market price of tert-butyl 6,7-dihydrothiazolo [5,4-c] pyridine-5 (4H) -carboxylate. This compound is also used in the fields of pharmaceutical research and development and organic synthesis, but its price often varies depending on quality, purity, supply and demand.
Looking at the past, in the chemical reagent market, if its purity is normal, the price per gram may be tens of yuan. However, if you want high purity, the price will jump. High purity, or used in fine scientific research experiments, its preparation is difficult, so the price is expensive. The price per gram may reach hundreds of yuan.
Also, if you buy in large quantities, negotiate with suppliers, or have the benefit of discounts. The larger the quantity, the more obvious the discount, and the price per gram may be slightly reduced. However, market conditions are fickle, and the price of raw materials, changes in processes, and policy regulations can all fluctuate the price of this compound. To know its exact price, it is appropriate to consult chemical reagent suppliers and chemical product trading platforms, and compare the prices of various companies.