tert-butyl 4-(aminocarbonyl)tetrahydropyridine-1(2H)-carboxylate

This is the chemical structure of tert-butyl 4- (carbamoyl) tetrahydropyridine-1 (2H) -carboxylate. In this compound, tert-butyl, i.e. -C (CH < unk >) < unk >, is a group with a specific steric resistance, attached to a specific position in the molecule. 4- (carbamoyl) moiety, carbamoyl-CONH < unk >, containing carbonyl (C = O) and amino (-NH < unk >), which is connected to the fourth position of the pyridine ring. The pyridine ring forms a tetrahydropyridine structure after hydrogenation, and the 1 (2H) -formate part refers to the tert-butyl formate structure-COO-tBu connected to the pyridine ring at position 1 (in the numbering system after hydrogenation). In this structure, the groups interact with each other, and the spatial arrangement coexists with electronic effects. Tert-butyl affects the spatial conformation and reactivity of molecules due to its large volume; carbamoyl groups can participate in hydrogen bonding and various chemical reactions; the presence of tetrahydropyridine rings endows molecules with specific stability and reaction check points; the tert-butyl formate part can undergo ester-related reactions under specific conditions. Overall, this chemical structure determines its physicochemical properties and potential chemical behaviors.

Tert-butyl 4- (carbamoyl) tetrahydropyridine-1 (2H) -carboxylate is a key compound in organic synthesis. Its main uses are complex and diverse, so let me tell you one by one.
In the field of pharmaceutical chemistry, it is often regarded as an important intermediate. Due to its structural properties, it can participate in many reactions, and then construct complex molecular structures with specific biological activities. In the process of many drug development, with the help of the reactive activity of this compound, drug molecules that interact with human physiological targets can be synthesized to achieve the purpose of treating diseases. For example, when developing drugs related to the nervous system, it can be used for structural modification and derivatization to obtain compounds with better pharmacological and pharmacokinetic properties. < Br >
In the field of materials science, it also has important functions. It can be used as a basic structural unit for building functional polymer materials. Through appropriate reactions, it is introduced into the polymer chain to endow the material with unique properties, such as improving the solubility, thermal stability or mechanical properties of the material. When preparing intelligent responsive polymer materials, its special structure may enable the material to respond to specific stimuli, such as temperature, pH value, etc., and exhibit unique phase transition or adsorption and desorption behaviors.
At the same time, it is a commonly used model substrate in the study of organic synthesis methodology. By studying various reactions in which they participate, such as nucleophilic substitution, addition, cyclization, etc., researchers explore new synthesis strategies and methods, optimize reaction conditions, and improve reaction efficiency, selectivity and atomic economy. This is of great significance for promoting the development of organic synthetic chemistry, and helps to develop more efficient and green synthesis routes to prepare more organic compounds with novel structures and unique properties.

To prepare tert-butyl 4- (carbamoyl) tetrahydropyridine-1 (2H) -carboxylate, there are many methods for its synthesis, which is now a commonly used method by Jun Chen.
First take a suitable pyridine derivative as the starting material, which needs to contain functional groups that can be converted into the target structure by reaction. Using a base as the catalyst, the pyridine derivative is reacted with a specific electrophilic reagent. The structure of the electrophilic reagent should be related to the group to be introduced into the target product. During the reaction, the base can promote the reaction between the nucleophile (pyridine derivative) and the electrophilic reagent, so that the two can be combined smoothly.
After the electrophilic substitution reaction is completed, the resulting product contains functional groups that need to be further converted. At this point, some functional groups can be reduced to the desired structure in the target product through a specific reduction reaction. For example, if the product contains suitable unsaturated bonds or reducible groups, select a suitable reducing agent and reduce it under appropriate reaction conditions to adjust the molecular structure.
Then, proceed to the introduction step of the carbamoyl group. Select a suitable carbamoyl reagent and react with the partially modified product in an appropriate reaction system. This step requires precise control of the reaction conditions, such as temperature, pH, etc., to ensure that the carbamoyl group can be accurately introduced to the target position.
Finally, proceed to the formation step of tert-butyl ester. In the presence of a catalyst, tert-butyl 4- (carbamoyl) tetrahydropyridine-1 (2H) -formate was synthesized by esterification reaction of tert-butyl alcohol and the corresponding esterification reagents. The whole synthesis process needs to pay attention to the fine regulation of the reaction conditions at each step to ensure that the reaction proceeds smoothly in the expected direction to improve the yield and purity of the product.

Tert-butyl 4- (carbamoyl) tetrahydropyridine-1 (2H) -carboxylic acid ester is one of the organic compounds. Its physical and chemical properties are unique, and it is crucial for chemical research and related fields.
In terms of its physical properties, under normal conditions, tert-butyl 4- (carbamoyl) tetrahydropyridine-1 (2H) -carboxylic acid esters are mostly solid. This compound has a specific melting point, but the exact value varies depending on the preparation method and purity. Generally speaking, its melting point is in a certain range, so its purity can be identified. Its appearance may be a white crystalline powder, uniform and delicate, and slightly shiny under light.
As for chemical properties, tert-butyl 4- (carbamoyl) tetrahydropyridine-1 (2H) -carboxylic acid esters contain active groups such as carbamoyl groups and carboxylic acid ester groups. Carbamoyl groups have certain nucleophilic properties and can react with many electrophilic reagents, such as acyl halides, acid anhydrides, etc., to form new amides. Carboxylic acid ester groups can be hydrolyzed into corresponding carboxylic acids and alcohols under suitable conditions. In alkaline environments, hydrolysis reactions are more likely to occur because bases can catalyze ester bond breaking. In addition, the pyridine ring of the compound also has certain chemical activity, which can participate in aromatic electrophilic substitution reactions, and the electron cloud density distribution characteristics on the pyridine ring determine its reaction check point and reactivity.
Tert-butyl 4- (aminoformyl) tetrahydropyridine-1 (2H) -carboxylic acid esters have been widely used in organic synthesis, pharmaceutical chemistry and other fields due to their unique physical and chemical properties, providing important raw materials and intermediates for the preparation of many compounds.

The price range of "tert-butyl 4- (carbamoyl) tetrahydropyridine-1 (2H) -carboxylate" in the market is difficult to determine. Due to many factors, its price can change significantly.
First, the price of raw materials is the key. The preparation of this compound requires specific raw materials. If the production of raw materials fluctuates, or is affected by supply and demand, the price of this compound will fluctuate. If raw materials are scarce or the production cost is high, the price of this compound will also rise.
Second, the preparation process is complicated, which also affects the price. If the process requires high precision technology and complex processes, the requirements for equipment and manpower are high, and the cost will increase, and the price will also rise. On the contrary, if the process is simple and mature, the cost will be reduced, and the price will also drop.
Third, the supply and demand relationship in the market is also an important factor. If there is a large demand for this compound in many industries, but the supply is limited, the price will tend to be higher; if there is less demand and more supply, the price will be under downward pressure.
Fourth, the difference between manufacturers also makes the price different. Large factories may be able to produce at a lower cost due to scale effects and technical advantages; small factories may be able to produce at a lower cost due to small scale, weak technology, higher costs, and different prices.
To sum up, in order to know the exact price range of this compound, it is necessary to carefully investigate the raw material market, process details, supply and demand conditions, and factory quotations, etc., in order to have a more accurate