TERT-BUTYL 4,7-DIHYDROFURO[2,3-C]PYRIDINE-6(5H)-CARBOXYLATE

"Tert-butyl" is a branched alkyl group containing four carbons. Its structure is fixed and resembles a branch of a tree. "4,7 - DIHYDROFURO [2,3 - C] PYRIDINE - 6 (5H) - CARBOXYLATE" This part is the heterocyclic structure of the core. " 4,7-Dihydro "indicates that there is a double-bond hydrogenation state in the ring;" Furano [2,3-C] pyridine "refers to the fused shape of the furan ring and the pyridine ring, and the two are connected at specific locations, like tenon-mortise joints;" 6 (5H) -tert-butyl carboxylate "indicates that there is a tert-butyl carboxylic acid ester group connected to the fused ring at 6 positions, just like a decoration at a specific location in the building. In summary, the chemical structure of this compound is composed of tert-butyl groups connected to the carboxylic acid ester position of a specific hydrogenated furanopyridine, and the structure is exquisite. It is like a combination of ancient mechanisms, and each part cooperates to build this unique chemical entity.

Tert-butyl 4,7-dihydrofurano [2,3-c] pyridine-6 (5H) -carboxylic acid ester, which has a wide range of uses. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of drug molecules with characteristic structures. Many new anti-hypertensive drugs, with their unique chemical structures, construct core pharmacoactive groups through specific reaction steps to achieve the effect of regulating blood pressure. It is also indispensable in the development of drugs for the treatment of neurological diseases. It helps to synthesize active ingredients that can precisely act on neurotransmitter receptors or ion channels, or can improve cognitive impairment and relieve symptoms of mental illness.
In the field of materials science, it can be used as a raw material for the preparation of special performance polymer materials. Copolymerization with specific monomers endows polymer materials with unique solubility, thermal stability and mechanical properties. For example, preparing smart polymer materials that respond to specific solvents and change their properties under environmental stimulation has potential applications in the field of drug sustained release and sensors. In the field of organic synthetic chemistry, as a reaction substrate or intermediate, it participates in many classic organic reactions, such as nucleophilic substitution, addition reactions, etc., to help build complex organic molecular structures, expand the research boundaries of organic synthetic chemistry, and lay the foundation for the creation of new functional materials and bioactive molecules.

The method of preparing tert-butyl 4,7-dihydrofurano [2,3-c] pyridine-6 (5H) -carboxylic acid esters is an important matter in organic synthesis. The synthesis paths are common and numerous.
First, it can be initiated through pyridine derivatives. Based on a specific pyridine compound, under suitable reaction conditions, the furan ring structure is introduced. First, under the action of base catalysis, such as potassium carbonate, in a suitable solvent, such as acetonitrile, heat and stir to promote the nucleophilic substitution reaction between the two to form a key intermediate. This intermediate is then reduced by a reducing step, such as using a reducing agent such as sodium borohydride, under mild conditions, the specific double bond on the pyridine ring is reduced to generate tert-butyl 4,7-dihydrofurano [2,3-c] pyridine-6 (5H) -carboxylate.
Second, furan derivatives can also be started. Choose a suitable furan compound, carboxylate it first, and react with carbon dioxide gas on a metal catalyst, such as a zinc catalyst, in a suitable solvent to form a carboxyl-containing furan derivative. After that, the derivative is esterified with tert-butyl alcohol and dehydrating agents, such as dicyclohexyl carbodiimide (DCC), in the presence of catalyst 4-dimethylaminopyridine (DMAP), and a pyridine ring is constructed. This process can use suitable nitrogen-containing reagents, such as pyridine amines, to condensate with carboxyl groups and other active check points in furan derivatives under acid catalysis, and gradually construct the pyridine ring structure, and finally obtain tert-butyl 4,7-dihydrofuro [2,3-c] pyridine-6 (5H) -carboxylic acid esters.
Furthermore, a cyclization strategy can be adopted. Using linear precursors containing both furan and pyridine partial structures as raw materials, under the catalysis of strong acids or metals, intramolecular cyclization reactions occur. For example, p-toluenesulfonic acid is used as a catalyst in a high-boiling solvent, heated and refluxed to promote the interaction of active groups in the molecule, forming the furanopyridine ring structure of the target product, and then generating tert-butyl 4,7-dihydrofurano [2,3-c] pyridine-6 (5H) -carboxylic acid esters.
The various synthesis methods have their own advantages and disadvantages, and they need to be carefully selected according to the availability of raw materials, the difficulty of controlling the reaction conditions, and the purity requirements of the target product.

The physical properties of this compound are known today as TERT - BUTYL 4,7 - DIHYDROFURO [2,3 - C] PYRIDINE - 6 (5H) -CARBOXYLATE. If you want to know its physical properties, I will describe it.
The physical properties of this compound are often in a specific shape or solid shape. If it is solid, its crystal form may be arranged in a way that is hard or hard. This is due to the force of the molecule. Its melting is important, which is the degree of the material from the solid to the liquid. With this melting, the molecule can obtain enough energy to overcome the lattice energy, the molecular distance increases, and the material is changed. The high and low molecular forces are closely related to each other. If there is an interaction between molecules, such as Vander force, etc., the melting phase will be high.
To the degree of boiling, the degree of liquid melting. At this degree, the molecular energy is sufficient to affect the beam on the surface of the liquid and escape into the boiling phase. The boiling is also affected by the molecular force and the molecular weight of the phase. The greater the molecular weight of the phase, the more the molecular force, and the higher the boiling.
In terms of solubility, this compound has different properties in different solubility. If the molecule has a low-quality basis, it may have some solubility in water; if the molecule is non-soluble, it is more soluble in non-soluble solutions such as benzene and carbon tetrachloride.
Its chemical properties are affected by the specific functions contained in the molecule. Such as carboxyl ester functionalities, it is easy to generate hydrolysis reactions. Under acidic or acidic components, the ester is cracked to form carboxylic acids and alcohols of the phase. Under the hydrolysis of the chemical components, the carboxylic acid generated can be reversed in one step.
In addition, the chemical properties of the chemical compounds or aromatics make them have a certain anti-reactive activity. It can generate additives and anti-reactive properties, such as additives such as pigments and acids, and modify the molecular properties. The aromatic acid can replace the anti-reactive acid and introduce other functionalities to derive a variety of derivatives to enrich its chemical properties.

Nowadays, there are compound names TERT - BUTYL 4,7 - DIHYDROFURO [2,3 - C] PYRIDINE - 6 (5H) -CARBOXYLATE, and its market prospects are not worth exploring. This compound is in the field of synthesis, or can be used as a kind of medicine, and is used for many biologically active molecules. As the biological industry flourishes, there is a growing demand for new active compounds. This compound can be used to synthesize specific molecules, or to meet new challenges.
In addition, there are also contracts in the field of materials. With the development of functional materials, there are compounds with special properties or can be used in the research of new materials. The characteristics of this compound, or to give materials special optical and other properties, and to show their skills in the fields of optical materials and other branches.
However, its market prospects also face many challenges. If the synthesis process is expensive and expensive, it must be developed and promoted in the market. Furthermore, peer-to-peer efforts are also important. If other similar compounds occupy the market first, the road to promotion will be multiplied. In addition, TERT - BUTYL 4,7 - DIHYDROFURO [2,3 - C] PYRIDINE - 6 (5H) -CARBOXYLATE The market prospects are both challenging and challenging, and it needs to be developed by colleagues in the industry.