tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridine-1(2H)-carboxylate

This is the problem of structural analysis of organic compounds. Tert-butyl 4- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -5,6-dihydropyridine-1 (2H) -carboxylate, according to its name, can be gradually analyzed its structure.
"tert-butyl", that is, tert-butyl, is a carbon chain branching structure, which is shaped like a claw and is connected to a central carbon with trimethyl groups. " 4 - (4,4,4,5,5 - tetramethyl - 1,3,2 - dioxaborolan - 2 - yl) "part, 4,4,4,5,5 - pentamethyl - 1,3,2 - dioxaborolan - 2 - group, which is a heterocyclic ring structure with a boron atom and two oxygen atoms, and five methyl groups are connected to the ring.
And" 5,6 - dihydropyridine - 1 (2H) -carboxylate ", 5,6 - dihydropyridine - 1 (2H) -carboxylate, revealing that the structure contains a dihydropyridine ring and has a carboxylate group at position 1.
In combination, the structure of this compound is composed of tert-butyl linked to the main chain containing a dihydropyridine ring, which is connected to a carboxylic acid ester group at 1 position and a 4-pentamethyl-1,3,2-dioxyboron heterocyclopentane-2-group at 4 positions. This structure integrates a variety of functional groups, and each functional group interacts with each other, giving the compound unique chemical properties. It may have specific uses and reactivity in the fields of organic synthesis, pharmaceutical chemistry, etc.

"Tert-butyl 4- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -5,6-dihydropyridine-1 (2H) -carboxylate", Chinese name or tert-butyl 4- (4,4,5,5-tetramethyl-1,3,2-dioxyboropentyl-2-yl) -5,6-dihydropyridine-1 (2H) -carboxylate. This compound has a wide range of uses, and listen to me one by one.
In the field of organic synthesis, it is often used as a key intermediate. The boron ester structure gives it unique reactivity and can participate in many important reactions, such as the Suzuki reaction. In this reaction, the compound can be coupled with halogenated aromatics or halogenated olefins under palladium catalysis, thereby forming a carbon-carbon bond. This is of great significance for the construction of complex organic molecular frameworks. In pharmaceutical chemistry, many drug molecule synthesis rely on this method to build specific structures.
In the field of materials science, it also contributes. By participating in polymerization reactions or chemically modifying with other functional materials, materials with specific photoelectric properties can be prepared. For example, when synthesizing boron-containing polymers, the compound is introduced into the boron ester unit, which can adjust the fluorescence properties and charge transport ability of the material, etc., which is extremely important for the research and development of organic Light Emitting Diodes (OLEDs), solar cells and other materials.
Furthermore, in the field of chemical biology research, it also plays a role. Due to the unique biological properties of boron, this compound can be modified for biological imaging or as a bioactive probe. The boron ester part may interact with specific molecules in organisms to achieve targeted labeling and detection of biomolecules, enabling researchers to explore complex physiological processes in organisms.

To prepare tert - butyl 4- (4,4,5,5 - tetramethyl - 1,3,2 - dioxaborolan - 2 - yl) -5,6 - dihydropyridine - 1 (2H) -carboxylate, there are various methods. The common method is to choose a starting material or a pyridine derivative with a suitable substituent.
First, a pyridine derivative with a corresponding halogenated group and a diphenacol borate are used as raw materials, and the boration reaction is carried out in the presence of a palladium catalyst, a ligand and and a base. Palladium catalysts such as palladium acetate, ligands such as tri-tert-butyl phosphine, bases such as potassium carbonate, etc. React in suitable organic solvents, such as dioxane and toluene, and heat to a certain temperature to couple halogenated pyridine with diphenol borate, and introduce boronyl ester groups. After appropriate treatment, such as separation and purification, the target product can be obtained.
Second, starting from carboxylic acid derivatives containing pyridine rings, the dihydropyridine ring structure can be constructed by a specific reaction, and then the boronyl ester group can be introduced in a suitable step. For example, pyridine-4-carboxylic acid derivatives are used to form dihydropyridine rings through reduction, cyclization, etc., and then boronyl ester groups are introduced by the above-mentioned boration reaction. During the process, attention should be paid to the control of reaction conditions, such as temperature, reaction time, material ratio, etc., due to different conditions or the yield and purity of the product. And the separation and purification operation after each step of the reaction is also crucial, which is related to the quality of the final product. All these are available routes for the synthesis of tert-butyl 4- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -5,6-dihydropyridine-1 (2H) -carboxylate.

Tert - butyl 4- (4,4,5,5 - tetramethyl - 1,3,2 - dioxaborolan - 2 - yl) - 5,6 - dihydropyridine - 1 (2H) - carboxylate is an organic compound. Its physicochemical properties are very important and are of key significance in chemical research and related application fields.
When it comes to physical properties, this compound may be a solid under normal conditions. Because its molecular structure contains specific functional groups and atomic arrangement, the intermolecular force causes it to be in a solid state. Its melting point may vary depending on the strength of intermolecular interactions, and the specific value needs to be accurately determined by experiments. However, it can be speculated that due to the existence of structures such as tert-butyl, borate ester and pyridine ring, the intermolecular force is strong, and the melting point may be relatively high.
Looking at its solubility, due to the polar borate group and the relatively non-polar tert-butyl and pyridine ring parts, it is soluble in organic solvents or has characteristics. In polar organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), the borate group can form hydrogen bonds or other interactions with solvent molecules, so it has a certain solubility; in non-polar solvents such as n-hexane, the solubility may be limited due to the non-polar partial action.
Chemical properties, the borate ester part has unique activity. It can participate in the Suzuki coupling reaction, which is an important organic reaction for building carbon-carbon bonds. In the presence of suitable bases and palladium catalysts, borate esters can react with halogenated aromatics or halogenated olefins to form new carbon-carbon bonds, which greatly expands their application in organic synthesis and can be used to construct complex organic molecular structures. The pyridine ring also gives it a certain alkalinity and can react with acids to form salt compounds. This property plays an important role in regulating the solubility and reactivity of compounds. In addition, the double-bonded part of the molecule can be added to further enrich its chemical reactivity, providing the possibility for the synthesis of more derivatives.

Eh, the name of this compound is "tert-butyl 4- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) -5,6-dihydropyridine-1 (2H) -carboxylate", which is widely used in the field of organic synthesis.
It is often a key building block for the construction of complex organic molecules. In the frontier of medicinal chemistry, this compound can be used as a key intermediate for the creation of novel and highly bioactive drug molecules. With its unique structure, boron-based functional groups can be ingeniously introduced. In subsequent reactions, such as palladium-catalyzed cross-coupling reactions, carbon-carbon and carbon-heteroatom bonds can be precisely constructed, laying the foundation for the synthesis of active molecules with unique structures.
In the field of materials science, the research and development of organic optoelectronic materials is crucial. This compound participates in the synthesis of conjugated polymers or small molecules with specific structures, which can effectively adjust the electronic structure and optical properties of materials. It is expected to be used in the preparation of high-performance organic Light Emitting Diodes (OLEDs), organic solar cell materials, etc. Because boron-based groups have a significant impact on the charge transport and luminescence properties of materials.
Furthermore, in the field of chemical biology, when exploring specific biological processes or labeling biomolecules in organisms, probe molecules or reagents containing this compound can use their reactivity to chemically modify and bind biomolecules specifically, helping researchers gain insight into the microscopic mysteries of living organisms.