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What is the chemical structure of Tert-butyl-2- (4- (pyridine-2-yl) benzyl) hydrazinecarboxylate
Eh! This "Tert - butyl - 2 - (4- (pyridine - 2 - yl) benzyl) hydrazinecarboxylate" is the name of the organic compound. To know its chemical structure, it is necessary to analyze the clues contained in its name.
"Tert - butyl", tert-butyl is also a branched chain alkyl group containing four carbons, and its structure is -C (CH). "hydrazinecarboxylate" shows that this compound contains the part of the hydrazine group and carboxylic acid ester, that is, the -NH - NH - COO - structural fragment. " 2 - (4 - (pyridine - 2 - yl) benzyl) "part," benzyl "is benzyl, that is, benzyl - CH -2 - C H," 4 - (pyridine - 2 - yl) "epipyridine - 2 - group is connected to the counterposition of benzyl. Pyridine - 2 - group is a 2-position substituent of the pyridine ring, and the pyridine ring has a six-membered nitrogen-containing aromatic ring structure.
In summary, the structure of this compound is as follows: tert-butyl is connected to a hydrazine-containing and carboxylic acid ester structure, and one end of this structure is connected with 4- (pyridine-2-yl) benzyl. Specifically, tert-butoxycarbonyl (-COOC (CH < Br >) is connected to one of the nitrogen atoms of the hydrazine group, and the other nitrogen atom of the hydrazine group is connected to the benzyl carbon of the 4- (pyridine-2-yl) benzyl group. In this way, the chemical structure of this compound can be understood.
What are the main uses of Tert-butyl-2- (4- (pyridine-2-yl) benzyl) hydrazinecarboxylate
Tert-butyl-2- (4- (pyridin-2-yl) benzyl) hydrazine carboxylate is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
It is the cornerstone of the delicate organic synthesis and the construction of many complex compounds. It can introduce specific functional groups through the chemical reactions it participates in to achieve the extension of the carbon chain and the remodeling of the structure.
It also plays an important role in the field of pharmaceutical chemistry. Due to its unique structure, it can be modified and optimized as a lead compound to help the development of new drugs. Or by leveraging its interaction with biological targets, explore new ways to treat diseases. < Br >
There are also potential applications in the field of materials science. Materials with special properties, such as functional materials with excellent optical and electrical properties, can be prepared through the polymerization reactions in which they participate, which contributes to the development of materials science.
This compound is like a key, opening the door to many fields such as organic synthesis, drug research and development, and material preparation, and plays an important role in the development of modern chemistry and related technologies.
What is the synthesis method of Tert-butyl-2- (4- (pyridine-2-yl) benzyl) hydrazinecarboxylate
Alas! To obtain tert - butyl - 2 - (4- (pyridine - 2 - yl) benzyl) hydrazinecarboxylate synthesis method, listen to me in detail.
Usually choose the starting material, or take 4 - (pyridine - 2 - yl) benzyl halide, this halide can be chloride, bromide, etc. Then take tert - butyl hydrazinecarboxylate react with it.
The reaction conditions are very critical. In an appropriate solvent, such as dichloromethane, N, N - dimethylformamide, etc., add an appropriate amount of bases, such as potassium carbonate, sodium carbonate, etc., to promote the reaction. The alkali can grab the ortho-hydrogen of the carbon attached to the halogen atom in the halide, which greatly increases the activity of the halide and makes it easier to undergo nucleophilic substitution reaction with the amino group of tert-butyl hydrazinecarboxylate.
When reacting, the temperature also needs to be controlled. Generally speaking, the reaction can occur smoothly at room temperature or slightly heated, such as 40-60 degrees Celsius. The reaction process needs to be monitored by thin-layer chromatography and other means. When the raw materials are exhausted, the reaction can be completed.
After the reaction is completed, the separation and purification of the product cannot be ignored. First, by the method of extraction, the product is enriched in the organic phase with a suitable organic solvent and the aqueous phase for many times. After column chromatography separation, select the appropriate silica gel column, with different proportions of eluent, such as petroleum ether and ethyl acetate mixture, gradually eluted, can obtain pure tert - butyl - 2 - (4 - (pyridine - 2 - yl) benzyl) hydrazinecarboxylate product. In this way, the synthesis method is complete.
What are the physical properties of Tert-butyl-2- (4- (pyridine-2-yl) benzyl) hydrazinecarboxylate
Tert-butyl-2 - (4- (pyridine-2-yl) benzyl) hydrazine carboxylate, this physical property is complex, let me explain in detail.
Looking at its properties, at room temperature, it is mostly white to white solid, with fine texture. Its melting point is quite critical, about [X] ° C. This melting point characteristic is crucial when identifying and purifying, just like the criterion for distinguishing between beautiful jade and stubborn stone.
Solubility is also its important physical property. In organic solvents, such as common ethanol and dichloromethane, it can show a certain solubility, just like fish entering water and fusing together. In water, the solubility is poor, just like oil and water are difficult to mix, and this property also provides convenience for separation and application.
In terms of stability, in conventional environments, it can be stable if it is protected from strong light, hot topics and humidity. In case of strong acid and alkali, it is like a weak body in case of strong wind and rain, which is easy to react and change the structure.
In terms of volatility, this compound has very little volatility and is not easy to escape into the air. If it is calm, it is not easy to spread.
The physical properties of tert-butyl-2 - (4- (pyridine-2-yl) benzyl) hydrazine carboxylic acid esters have their own uses, and they are all indispensable considerations in the fields of chemical industry, pharmaceutical research and development, just like in a delicate chess game, each chess piece has a unique function, which is related to the success or failure of the whole situation.
What is the market outlook for Tert-butyl-2- (4- (pyridine-2-yl) benzyl) hydrazinecarboxylate?
Tert - butyl - 2 - (4 - (pyridine - 2 - yl) benzyl) hydrazinecarboxylate this product, which has a promising market prospect today.
It is one of the important intermediates in the field of organic synthesis and has attracted much attention in the field of medicinal chemistry. In terms of drug research and development, the creation of many innovative drugs depends on such compounds as the cornerstone. Its unique molecular structure gives it the potential to bind specifically to biological targets, so it is often the focus of researchers in the process of anti-cancer and anti-infection drug development. Nowadays, cancer and infectious diseases are serious diseases that endanger human health, and the demand for new specific drugs is eager. Tert-butyl-2 - (4 - (pyridine-2 - yl) benzyl) is hydrazinecarboxylate in the market of anti-cancer and anti-infective drug research and development. There is great potential, and the demand may be growing.
Furthermore, in the field of materials science, it has also emerged. With the rapid development of science and technology, there is a growing demand for materials with special properties. This compound has potential application value in the fields of optical materials and adsorption materials due to its own structural characteristics, or it can be introduced into the material system by specific means to endow materials with specific properties such as fluorescence and adsorption. Although the relevant application research may not be mature at present, the prospect is promising. With time, when the technology breaks through, the market space will also expand.
However, the progress of its market is not smooth. The complexity of the synthesis process has resulted in high production costs, which is one of the major factors hindering its marketing activities. And similar substitutes also exist in the market, and the trend of competition cannot be underestimated. Looking at the overall situation, with the advancement of technology, the synthesis process may be optimized, and the cost will drop; and its unique properties, if well explored, will be able to open up the market in emerging fields, and the future will be bright.