As a leading (S)-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of (S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -1H-pyrrolo [2,3-b] pyridine
(2S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -1H-pyrrolo [2,3-b] pyridine is an organic compound. Its physical properties are as follows:
From the perspective of normal temperature and pressure, it is mostly in a solid state, which is caused by intermolecular forces and crystal structure. As for the color, the pure one is often white or almost white powder, but if it contains impurities, the color may change.
When it comes to solubility, the compound exhibits a certain solubility in organic solvents such as dichloromethane, chloroform, tetrahydrofuran, etc. The molecular structure contains parts that interact with organic solvents, which is in line with the principle of similar compatibility. However, in water, the solubility is quite low, because the overall hydrophobicity of the molecule is strong, and the interaction between water molecules and it is weak.
In terms of melting and boiling point, the melting point may be within a certain range, and the specific value is determined by factors such as intermolecular forces and crystal accumulation methods. Generally speaking, the melting point of organoboron compounds is different from common hydrocarbons due to the regularity of boron atoms participating in bonding and molecular structure. The boiling point is also affected by the size of intermolecular forces and molecular weight. It is relatively high, and a suitable temperature is required to make it boil into a gaseous state.
In terms of density, compared with water, its density may vary depending on molecular composition and structure. The density of organoboron compounds is often between a certain range, but the exact value needs to be accurately determined by experiments.
All the above physical properties are of critical significance in the synthesis, separation, purification and practical application of the compound. During synthesis, solubility can help to select suitable reaction solvents; during separation and purification, melting boiling point properties can be used to select suitable methods such as distillation and recrystallization; in practical applications, these properties may affect their dispersion and mixing behaviors in specific systems.
What are the chemical synthesis methods of (S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -1H-pyrrolo [2,3-b] pyridine
The chemical synthesis method of (S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) -1H-pyrrolido [2,3-b] pyridine is quite complicated, and this is a detailed description for you.
To synthesize this compound, a common number method is used. First, a compound containing pyridine and pyrrole structures is used as the starting material. First, the structure of pyridine and pyrrole is properly functionalized, and a suitable substituent is introduced at a specific position of pyridine, and the parent nucleus of pyrrolido [2,3-b] pyridine is constructed through multi-step reaction.
After the construction of the parent nucleus is completed, the boron ester group needs to be introduced. The commonly used method is to use halogenated pyridine derivatives and diphenacol borate in a suitable metal catalyst, such as palladium catalyst, such as tetra (triphenylphosphine) palladium, etc. The coupling reaction occurs in a basic environment. The basic conditions can be provided by bases such as potassium carbonate and sodium carbonate, and this reaction can effectively introduce 4,4,5,5-tetramethyl-1,3,2-dioxoboronacyclopentane-2-groups into the target molecule.
When introducing the methyl moiety, suitable methylation reagents, such as iodomethane, dimethyl sulfate, etc. can be selected at an appropriate stage of the reaction. In the presence of a base, substitution reactions occur with the corresponding hydroxyl or amino groups and other active check points to achieve the introduction of methyl groups, thereby completing the synthesis of (S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxoboronacyclopentane-2-yl) -1H-pyrrolido [2,3-b] pyridine. However, the synthesis path requires fine control of reaction conditions, such as temperature, time, reagent dosage, etc., in order to obtain satisfactory yield and purity.
What is the main application field of (S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -1H-pyrrolo [2,3-b] pyridine
(S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxoboran-2-yl) -1H-pyrrolido [2,3-b] pyridine The main application field of this product is related to the field of medical chemistry and materials science.
In medical chemistry, it plays a key role. Compounds containing boron and pyridine structures often have unique biological activities. Such structures can precisely bind to proteins, enzymes and other targets in organisms, or interfere with specific biological signaling pathways to exhibit antibacterial, anti-inflammatory, anti-tumor and other pharmacological effects. For example, in the research and development of many new anti-cancer drugs, the impact of such structures on the proliferation and apoptosis of cancer cells has been focused on, hoping to use their unique activities to find new ways for cancer treatment.
In the field of materials science, it also has its own unique features. Boron and pyridine structures endow compounds with special optoelectronic properties, which can be used to prepare organic optoelectronic materials. For example, in the field of organic Light Emitting Diode (OLED), the characteristics of such compounds can be used to optimize the performance of devices such as luminous efficiency and stability. When preparing high-performance OLED displays, the rational use of this compound is expected to improve the screen display quality, achieve better color performance and energy consumption control.
To sum up, (S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboropentyl-2-yl) -1H-pyrrolido [2,3-b] pyridine has high research value and application potential in the fields of medicine and materials science, which is like the key to opening the door to innovation in two fields.
What is the market outlook for (S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -1H-pyrrolo [2,3-b] pyridine?
Now there is (2S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboronheterocyclopentane-2-yl) -1H-pyrrolido [2,3-b] pyridine. What is the market prospect of this compound? Let me tell you in detail.
(2S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboronheterocyclopentane-2-yl) -1H-pyrrolido [2,3-b] pyridine has a promising future in the field of pharmaceutical chemistry. Due to its unique structure, it can be used as a key intermediate for the synthesis of a variety of biologically active molecules. In the development process of many innovative drugs, such compounds containing boron and pyrrolidine structures often demonstrate high selectivity and affinity for specific biological targets, and are expected to become potential drugs for the treatment of major diseases such as cancer and neurological diseases.
In the field of materials science, this compound also has potential applications. The structure of boron heterocyclopentane gives it special electronic and optical properties, or it can be used in organic Light Emitting Diode (OLED) materials, fluorescent probes and other fields. With the advance of science and technology, there is an increasing demand for materials with unique optoelectronic properties. (2S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxoboronheterocyclopentane-2-yl) -1H-pyrrolido [2,3-b] pyridine can provide a novel structural basis or make a name for itself in innovative applications of materials.
However, its marketing activities also face some challenges. Optimization of the synthesis process is essential, and it is necessary to improve the yield and reduce the cost in order to facilitate large-scale production and market popularization. And related research is still in the development stage, and the comprehensive understanding of its performance and application needs to be further explored. Despite this, considering its potential value in the fields of medicine and materials, (2S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) -1H-pyrrolido [2,3-b] pyridine has promising future market prospects. With time and effort, it may be able to shine in many fields.
(S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -1H-pyrrolo [2,3-b] pyridine What are the precautions during storage and transportation
(S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxaboronheterocyclopentane-2-yl) -1H-pyrrolido [2,3-b] pyridine is an organic compound. During storage and transportation, several things need to be paid attention to.
Temperature and humidity of first storage. This compound should be placed in a dry and cool place to avoid high temperature and humidity. High temperature can cause its structure to change or initiate chemical reactions; humid environment may cause it to absorb moisture, affecting purity and stability. If it exists in high temperature and humidity, there is a risk of deterioration, such as color change, odor, etc., which will damage quality and utility. < Br >
Second, to avoid light. Light can cause photochemical reactions, causing damage to the molecular structure of the compound. Therefore, when storing, it should be contained in an opaque container, or stored in a dark place, such as in a brown bottle, and placed in a cabinet and other light-proof places to ensure its chemical stability.
When transporting, the packaging must be stable. Because it is mostly in solid or liquid form, it is necessary to ensure that the packaging can withstand a certain amount of external force, so as not to be damaged and leaked during handling. Wrap with strong packaging materials, such as suitable glass or plastic bottles, and protect with cushioning materials to prevent collisions and vibrations.
Furthermore, temperature control is also required during transportation. Do not expose it to extreme temperature conditions, according to its characteristics, choose the appropriate mode of transportation and environment. During long-distance transportation, cold chain transportation or other means may be used to ensure that its quality is not affected by temperature fluctuations.
In short, proper storage and transportation can ensure that (S) -methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxaboronheterocyclopentane-2-yl) -1H-pyrrolido [2,3-b] pyridine has stable quality and chemical properties, and will play its due role in subsequent applications.