S 4 5 6 7 Tetrahydro 3 Phenylmethyl 3h Imidazo 4 5 C Pyridine 6 Carboxylic Acid Dihydrochloride
pyridine pyrrole pyrazine piperidine piperazine

(S)-4,5,6,7-Tetrahydro-3-phenylmethyl-3H-imidazo[4,5-c]pyridine-6-carboxylic acid dihydrochloride

    Specifications

    HS Code

    958028

    Chemical Name (S)-4,5,6,7-Tetrahydro-3-phenylmethyl-3H-imidazo[4,5-c]pyridine-6-carboxylic acid dihydrochloride
    Molecular Formula C16H19Cl2N3O2
    Molecular Weight 356.247
    Appearance Solid (likely powder based on common form of such compounds)
    Physical State At Room Temp Solid
    Solubility Solubility characteristics would depend on solvent; may be soluble in polar solvents like water due to the carboxylic acid and hydrochloride groups
    Pka The carboxylic acid group would have a pKa in the range typical for carboxylic acids, around 4 - 5, and the nitrogen - containing heterocyclic part may also have relevant pKa values for protonation/deprotonation
    Chirality Exists in (S)-configuration, indicating a specific stereochemistry
    Melting Point A defined melting point which is characteristic of the compound, but exact value requires experimental determination
    Chemical Stability Stability can be affected by factors like heat, light, and moisture; the hydrochloride salts may be hygroscopic

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    General Information
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    Frequently Asked Questions

    As a leading (S)-4,5,6,7-Tetrahydro-3-phenylmethyl-3H-imidazo[4,5-c]pyridine-6-carboxylic acid dihydrochloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of (S) -4, 5, 6, 7-Tetrahydro-3-phenylmethyl-3H-imidazo [4,5-c] pyridine-6-carboxylic acid dihydrochloride
    (S) -4,5,6,7-tetrahydro-3-benzyl-3H-imidazolo [4,5-c] pyridine-6-carboxylic acid dihydrochloride, which is an organic compound. Its chemical structure is composed of many parts and can be inferred according to chemical nomenclature.
    Looking at its main body, imidazolo [4,5-c] pyridine is the core parent ring, which is a nitrogen-containing heterocyclic structure. It is fused by imidazole ring and pyridine ring, and has unique electron cloud distribution and chemical activity. In the third position of the mother ring, there is a benzyl group, that is, a benzyl group, which is a group connected to the benzene ring and methylene. The conjugate system of the benzene ring imparts specific physical and chemical properties to the molecule, such as increasing hydrophobicity and stability. In the sixth position, there is a carboxyl group, -COOH group, which is acidic and can participate in a variety of chemical reactions, such as salt formation, esterification, etc.
    4,5,6,7-tetrahydro indicates that the double bonds at the 4,5,6,7 positions in the mother ring are reduced to single bonds, resulting in a decrease in the degree of unsaturation of the molecule and changes in stability and physical properties. In addition, the compound exists in the form of dihydrochloride, which means that the molecule binds to two molecules of hydrogen chloride to form a salt compound and enhances its solubility and ionic properties in water.
    In summary, the chemical structure of (S) -4,5,6,7-tetrahydro-3-benzyl-3H-imidazolo [4,5-c] pyridine-6-carboxylic acid dihydrochloride is composed of specific mother rings, substituents and salt-forming forms. The interaction of each part determines its chemical and physical properties.
    What are the physical properties of (S) -4, 5, 6, 7-Tetrahydro-3-phenylmethyl-3H-imidazo [4,5-c] pyridine-6-carboxylic acid dihydrochloride
    (S) -4,5,6,7-tetrahydro-3-benzyl-3H-imidazolo [4,5-c] pyridine-6-carboxylic acid dihydrochloride, which is an organic compound. Looking at its physical properties, it is mostly in the state of white to off-white crystalline powder under normal conditions, which is conducive to observation and resolution.
    When it comes to solubility, it can show certain solubility properties in water. Due to the existence of groups that can interact with water molecules in the molecular structure, this property makes it better able to disperse and participate in reactions in chemical reactions or pharmaceutical preparations using water as a medium. In organic solvents, such as methanol, ethanol and other common organic solvents, it also has a certain solubility, but the degree of solubility may vary due to the difference in the force between the solvent molecule and the compound molecule.
    Its melting point is also one of the important physical properties. The accurate measurement of the melting point can provide a key basis for the determination of the purity of the compound. When it is heated, with the increase of temperature, the molecular vibration intensifies, and to a specific temperature range, the lattice structure disintegrates, and the compound changes from a solid state to a liquid state. This temperature is the range where the melting point is located.
    In addition, although the density of the compound is often the focus of attention, in a specific chemical production or preparation process, density information is also indispensable if the relationship between material dosage and volume needs to be accurately controlled. It reflects the mass per unit volume of a substance and provides a quantitative reference for production operations.
    Its physical properties such as appearance, solubility, melting point and density are interrelated and affect the application and research of the compound in different fields, such as medicinal chemistry and organic synthetic chemistry.
    What is the main use of (S) -4, 5, 6, 7-Tetrahydro-3-phenylmethyl-3H-imidazo [4,5-c] pyridine-6-carboxylic acid dihydrochloride
    (S) -4,5,6,7-tetrahydro-3-phenylmethyl-3H-imidazolo [4,5-c] pyridine-6-carboxylic acid dihydrochloride This substance has a wide range of uses. In the field of medicine, it is often an important intermediate for the creation of new drugs. Due to its unique structure and ability to interact with specific targets in the body, it plays a key role in the development of drugs for specific diseases, or can be used to treat diseases such as nervous system disorders and cardiovascular diseases.
    It is also an indispensable raw material in the field of chemical synthesis. With its own structural characteristics, it can participate in multiple chemical reactions, facilitate the construction of complex organic compounds, and provide an opportunity for the synthesis of novel molecules with specific functions. In the eyes of organic synthesis chemists, it is a powerful tool to expand the chemical space and explore the properties and functions of new substances.
    Furthermore, at the level of biological activity research, this compound can be used as a probe to deeply explore the biochemical processes in organisms. By observing its interactions with biological macromolecules, scientists can gain insight into the mysteries of life activities, contribute to basic research in life sciences, further clarify the mechanism of disease occurrence, and lay the foundation for future drug development and treatment strategies.
    What are the synthesis methods of (S) -4, 5, 6, 7-Tetrahydro-3-phenylmethyl-3H-imidazo [4,5-c] pyridine-6-carboxylic acid dihydrochloride
    To prepare (S) -4,5,6,7-tetrahydro-3-benzyl-3H-imidazolo [4,5-c] pyridine-6-carboxylic acid dihydrochloride, there are many methods, one of which is described in detail below.
    First take a suitable pyridine derivative as the starting material. This material needs to have a clear structure and good purity. It is the reaction base. In a suitable reaction vessel, add the pyridine derivative and an appropriate amount of organic solvent, such as dichloromethane, N, N-dimethylformamide, etc., to make the material uniformly dispersed and create a good reaction environment.
    Subsequently, a benzylation reagent, such as benzyl halide, and an appropriate amount of alkali, such as potassium carbonate, sodium carbonate, etc., are added to catalyze the benzylation reaction. Temperature control is moderate, usually at room temperature or slightly higher temperature, depending on the specific reaction process. During this period, intermolecular interactions, benzyl is gradually introduced into pyridine derivative molecules to form key intermediates.
    This intermediate is then reacted with tetrahydro, mostly using hydrogen as a hydrogen source, with suitable catalysts, such as palladium-carbon catalysts. In an autoclave, adjust the hydrogen pressure and temperature to hydrogenate the double bonds on the pyridine ring to form a tetrahydropyridine structure. This step requires careful operation to ensure that the reaction is complete and to prevent damage to the product structure caused by excessive hydrogenation.
    Next, carboxylation is carried out for the resulting product. Select a suitable carboxylation reagent, such as carbon dioxide or a specific carboxylic acid derivative, and react under specific conditions. Or mediated by organometallic reagents, the molecule is successfully introduced into the carboxyl group to obtain (S) -4,5,6,7-tetrahydro-3-benzyl-3H-imidazolo [4,5-c] pyridine-6-carboxylic acid.
    Finally, dissolve the carboxylic acid product in a suitable solvent, such as a mixed solvent of ethanol and water, slowly introduce hydrogen chloride gas, or add a suitable hydrogen chloride donor to form (S) -4,5,6,7-tetrahydro-3-benzyl-3H-imidazolo [4,5-c] pyridine-6-carboxylic acid dihydrochloride. After the reaction is completed, the purified product is obtained through crystallization, filtration, drying and other purification steps.
    Throughout the synthesis process, the reaction conditions of each step need to be precisely controlled, and the proportion of materials, temperature and time are all key, so that the target product can be obtained efficiently and with high purity.
    (S) -4, 5, 6, 7-Tetrahydro-3-phenylmethyl-3H-imidazo [4,5-c] pyridine-6-carboxylic acid dihydrochloride What are the precautions in use
    (S) - 4,5,6,7 - tetrahydro - 3 - benzyl - 3H - imidazolo [4,5 - c] pyridine - 6 - carboxylic acid dihydrochloride is a special chemical substance, and many key matters need to be paid attention to in use.
    First of all, this chemical substance has specific chemical activities and reaction characteristics. Because its structure contains imidazolopyridine core and related substituents, when mixing with other substances or participating in the reaction, the reaction conditions need to be carefully considered. For example, temperature control is very critical. Excessive temperature may cause it to decompose or initiate side reactions. Too low temperature may slow the reaction rate and make it difficult to achieve the desired effect. Furthermore, the pH of the reaction system cannot be ignored. Different acid and alkali environments may greatly affect its chemical behavior, or cause changes in activity, or generate different products.
    Secondly, safety protection is of paramount importance. This substance may be toxic and irritating to a certain extent, and protective measures must be taken during operation. Wear protective clothing, protective gloves and goggles to avoid contact with skin and eyes. In case of inadvertent contact, rinse with plenty of water immediately and seek medical attention according to specific circumstances. At the same time, the operation should be carried out in a well-ventilated place to prevent inhalation of dust or volatile gases of the substance, which may endanger the respiratory system.
    In addition, storage requirements should also be taken seriously. Store in a dry, cool and ventilated place, away from fire sources and oxidants. It may cause a safety accident due to its violent reaction with oxidants. And it needs to be sealed and stored to prevent moisture or reaction with components in the air, which will affect its quality and performance.
    In short, when using (S) -4,5,6,7-tetrahydro-3-benzyl-3H-imidazolo [4,5-c] pyridine-6-carboxylic acid dihydrochloride, it is necessary to fully understand its chemical properties, strictly follow the operating specifications, and do a good job of safety protection and storage to ensure that the use process is safe and secure and achieves the intended purpose.