S 2 Oxo 1 2 5 7 Tetrahydrospiro Cyclopenta B Pyridine 6 3 Pyrrolo 2 3 B Pyridine 3 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

(S)-2-oxo-1,2,5,7-Tetrahydrospiro[cyclopenta[b]pyridine-6,3-pyrrolo[2,3-b]pyridine]-3-carboxylic acid

    Specifications

    HS Code

    709356

    Chemical Formula C15H11N3O3
    Molecular Weight 281.27 g/mol
    Appearance Solid (presumed, based on similar compounds)
    Solubility In Water Low (due to non - polar cyclic structure and limited polar groups)
    Solubility In Organic Solvents Soluble in polar organic solvents like DMSO, DMF (expected)
    Chirality Chiral, (S)-configuration
    Stability Stable under normal conditions, may degrade under strong acids, bases or high heat

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    General Information
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    Frequently Asked Questions

    As a leading (S)-2-oxo-1,2,5,7-Tetrahydrospiro[cyclopenta[b]pyridine-6,3-pyrrolo[2,3-b]pyridine]-3-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of (S) -2-oxo-1,2,5,7-Tetrahydrospiro [cyclopenta [b] pyridine-6,3-pyrrolo [2,3-b] pyridine] -3-carboxylic acid?
    This is a difficult problem in organic chemistry. To solve the chemical structure of " (S) -2-oxo-1,2,5,7-tetrahydrospiro [cyclopento [b] pyridine-6,3-pyrrolio [2,3-b] pyridine] -3-carboxylic acid", it is necessary to study its naming rules in detail.
    Looking at its name, the word "spiro" indicates that this is a spiro-ring compound. The so-called spiro ring is that the two rings share one atom. Here "spiro [cyclopento [b] pyridine-6,3-pyrrolido [2,3-b] pyridine]" indicates that this compound is composed of cyclopento [b] pyridine and pyrrolido [2,3-b] pyridine. Two parts are connected by spiro atoms. Among them, cyclopento [b] pyridine and pyrrolido [2,3-b] pyridine form rings and are connected at spiro atoms. The configuration of the chiral center of
    " (S) " is S-type. Chiral, like human hands, although similar but cannot overlap. There are chiral centers in this compound, which are determined to be S-configuration according to specific rules.
    "2-oxo" means that there is a carbonyl group (C = O) at position 2 in the molecule. Carbonyl is a common functional group in organic compounds and has unique chemical properties.
    "1,2,5,7-tetrahydro" indicates that on the carbon atoms at positions 1, 2, 5, and 7, the original double bond or triple bond is added by the hydrogen atom to form a saturated carbon-carbon single bond structure.
    "-3-carboxylic acid" indicates that at position 3 of the spiral ring structure, a carboxyl group (-COOH) is connected. Carboxyl groups are also common functional groups, acidic, and can participate in many chemical reactions.
    In summary, the structure of this compound consists of a helical ring structure as the core, containing a specific chiral center, and functional groups such as carbonyl, carboxyl, and hydrogenated carbon-carbon bonds at specific positions, which combine with each other to form its unique chemical structure.
    What are the physical properties of (S) -2-oxo-1,2,5,7-Tetrahydrospiro [cyclopenta [b] pyridine-6,3-pyrrolo [2,3-b] pyridine] -3-carboxylic acid?
    (2S) -2-oxo-1,2,5,7-tetrahydrospiro [cyclopento [b] pyridine-6,3-pyrrolo [2,3-b] pyridine] -3-carboxylic acid, this is an organic compound. Looking at its structure, the unique structure of the spiral ring system endows it with other physical properties.
    First of all, its solubility is due to the fact that there are both polar carboxyl groups in the molecule and non-polar cyclic structures. Polar carboxyl groups can form hydrogen bonds with water, but non-polar cyclic structures prevent them from dissolving in water. Therefore, its solubility in water should be limited, or slightly soluble in water. In polar organic solvents such as methanol and ethanol, the solubility may be improved due to the formation of hydrogen bonds or similar polarity with the solvent; in non-polar organic solvents such as n-hexane, because the non-polar part is not enough to interact with the solvent, it may be difficult to dissolve.
    When it comes to the melting point, in view of the existence of hydrogen bonds between its molecules, especially between carboxyl groups, hydrogen bonds can be formed. To make the molecules break free from each other, more energy is required. Therefore, it is speculated that the melting point should not be low. And the rigid helical structure of the molecule makes the molecular arrangement more regular and tight, which will also promote the increase of the melting boiling point. < Br >
    Again, density, because the molecular structure contains polycyclic, atoms are relatively concentrated, the mass is large, and the spatial structure is compact, resulting in an increase in mass per unit volume, so its density or more common small molecule organic compounds are larger.
    As for stability, although the helical structure has a certain tension, the interring conjugation effect can compensate the tension energy to a certain extent, so that the whole molecule remains relatively stable. However, the carboxyl group has certain reactivity, and under specific conditions, it may participate in reactions such as esterification and salt formation, which affects its stability.
    (S) -2-oxo-1,2,5,7-Tetrahydrospiro [cyclopenta [b] pyridine-6,3-pyrrolo [2,3-b] pyridine] -3-carboxylic acid What are the synthesis methods?
    The synthesis of (S) -2-oxo-1,2,5,7-tetrahydrospiro [cyclopento [b] pyridine-6,3-pyrrolo [2,3-b] pyridine] -3-carboxylic acid is an important topic in the field of organic synthesis. This compound has a unique structure and requires a delicate strategy for synthesis.
    To synthesize this compound, you can start by building a key skeleton. First, you can prepare a cyclopento [b] pyridine-containing structural fragment first, and use a suitable pyridine derivative as the starting material, and use nucleophilic substitution or cyclization to build this part of the structure. For example, the halogen atom at a specific position on the pyridine reacts with a nucleophile containing a cyclopentyl group to form a preliminary carbon-carbon bond, and then the cyclopento [b] pyridine structure is obtained by intramolecular cyclization.
    Second, the construction of the pyrrolido [2,3-b] pyridine part can be synthesized by means of nitrogen-containing heterocyclic synthesis. The pyrrole derivative is used as a base, condensed with a carbonyl compound, and then cyclized to construct the pyrrolido [2,3-b] pyridine structure. This process requires precise control of the reaction conditions to obtain the desired regioselectivity and stereochemistry.
    Subsequently, the two key structural fragments are connected, and transition metal-catalyzed coupling reactions, such as palladium-catalyzed cross-coupling, can be used. During the reaction, careful selection of ligands and bases is required, and the reaction temperature and time are optimized to improve the bonding efficiency and product purity.
    Synthesis of (S) -2-oxo-1,2,5,7-tetrahydrospiro [cyclopento [b] pyridine-6,3-pyrrolido [2,3-b] pyridine] -3-carboxylic acid. The reaction conditions and reagent selection at each step are crucial. Careful design and regulation are required to achieve efficient and highly selective synthesis.
    (S) -2-oxo-1,2,5,7-Tetrahydrospiro [cyclopenta [b] pyridine-6,3-pyrrolo [2,3-b] pyridine] -3-carboxylic acid What are the application fields?
    (2S) -2-oxo-1,2,5,7-tetrahydrospiro [cyclopento [b] pyridine-6,3-pyrrolo [2,3-b] pyridine] -3-carboxylic acid, this compound is quite useful in the fields of medicine and chemical industry.
    In the field of medicine, it seems to be a drug intermediate with extraordinary potential. Due to its unique chemical structure, it can be cleverly modified to meet the needs of specific targets, thereby enabling the creation of new drugs. For example, for some specific disease-related protein targets, it can be structurally modified to make it interact with the target precisely, or excellent anti-cancer and anti-inflammatory drugs can be developed, bringing good news to patients. < Br >
    In the chemical industry, it can be used as a key component of functional materials. With its special chemical properties, it may endow materials with unique physical and chemical properties. If the compound is introduced into polymer materials, it may improve the stability and solubility of the material, so that the material can show more excellent performance in the manufacture of coatings, plastics and other products, and expand the application scope of chemical products.
    And because of its complexity and uniqueness of structure, it is also an excellent model substrate for researchers to study new synthesis methods and strategies in the field of organic synthetic chemistry. Through the exploration and optimization of its synthesis route, it can promote the progress of organic synthesis technology and provide ideas and reference for the synthesis of more complex compounds.
    What is the market outlook for (S) -2-oxo-1,2,5,7-Tetrahydrospiro [cyclopenta [b] pyridine-6,3-pyrrolo [2,3-b] pyridine] -3-carboxylic acid?
    (S) -2-oxo-1,2,5,7-tetrahydrospiro [cyclopento [b] pyridine-6,3-pyrrolio [2,3-b] pyridine] -3-carboxylic acid, which is a rather complex organic compound. In terms of the current market prospect, it presents a situation of coexistence of opportunities and challenges.
    From the perspective of the field of pharmaceutical research and development, such compounds with unique structures may contain potential biological activities. Due to their special spiral structure, they may have unique interactions with specific biological targets, so they have certain exploration value in the development of innovative drugs. Many pharmaceutical companies and scientific research institutions have always been enthusiastic about conducting research on novel compounds, hoping to find lead compounds that can treat specific diseases. If (S) - 2 - oxo - 1,2,5,7 - tetrahydrospiro [cyclopento [b] pyridine - 6,3 - pyrrolido [2,3 - b] pyridine] - 3 - carboxylic acid has been confirmed to have good pharmacological activity and can pass the subsequent pharmacological evaluation, it is expected to become an important part of new drugs, and the market prospect is quite promising.
    However, it also faces many challenges. The synthesis of such complex compounds often requires superb synthesis technology and complicated synthesis steps, which will undoubtedly lead to a significant increase in production costs. And in the process of drug development, safety and efficacy evaluation also requires a lot of time and resources. If it cannot pass the clinical trials and other links smoothly, the early investment may be wasted.
    Looking at other fields such as materials science, although there are no specific application reports for such compounds, with the continuous development of materials science, the demand for compounds with special structures and properties is also gradually increasing. If follow-up research can uncover its unique properties in materials, such as special optical and electrical properties, it may also open up new application fields and market space.
    In summary, (S) - 2 - oxo - 1,2,5,7 - tetrahydrospiro [cyclopento [b] pyridine - 6,3 - pyrrolio [2,3 - b] pyridine] - 3 - carboxylic acid market prospects are full of uncertainty, but with its unique structure, it still has a certain development opportunity in medicine and other potential fields, worthy of scientific researchers and related industry personnel to pay attention and explore.