R Alpha Methyl 4 Pyridinemethanol
pyridine pyrrole pyrazine piperidine piperazine

(R)-(+)-alpha-Methyl-4-pyridinemethanol

    Specifications

    HS Code

    116719

    Chemical Formula C7H9NO
    Molecular Weight 123.152 g/mol
    Cas Number 56746-76-4
    Appearance Solid
    Boiling Point 275.5°C at 760 mmHg
    Melting Point 78 - 82°C
    Density 1.089 g/cm³
    Flash Point 120.4°C
    Solubility In Water Soluble
    Refractive Index 1.545

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    General Information
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    Frequently Asked Questions

    As a leading (R)-(+)-alpha-Methyl-4-pyridinemethanol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of (R) - (+) -alpha-Methyl-4-pyridinemethanol?
    (R ) - ( + ) -α - methyl-4-pyridyl methanol, is one of the organic compounds. Its chemical structure is unique, composed of a pyridine ring with a methanol group and a methyl group. The pyridine ring is a nitrogen-containing six-membered heterocycle with aromatic properties. In this structure, the fourth carbon of the pyridine ring is connected with a methanol group, and the α carbon connected to it has a methyl group.
    Looking at its structure, the nitrogen atom of the pyridine ring is given a certain alkalinity. Because the nitrogen atom has a lone pair of electrons, it can accept protons. The existence of the methanol group makes the compound have a certain hydrophilicity, because the hydroxyl group can form a hydrogen bond. The presence of α-methyl may affect the spatial configuration and electron cloud distribution of the molecule.
    Furthermore, (R ) - ( + ) -α - the name of methyl-4-pyridyl methanol, (R) indicates its absolute configuration, according to the Cahn-Ingold-Prelog rule; (+) indicates its optical rotation is right-handed. This structural property may be of great significance in the fields of organic synthesis, medicinal chemistry, etc., or can be used as a synthetic intermediate to prepare compounds with specific biological activities.
    What are the main physical properties of (R) - (+) -alpha-Methyl-4-pyridinemethanol?
    (R ) - ( + ) -α - methyl-4-pyridylmethanol is an important compound in the field of organic chemistry. Its main physical properties are described as follows:
    In terms of appearance properties, it is usually in the state of white to off-white crystalline powder, which makes it easy to handle and identify in many chemical operations and applications.
    Melting point is also a key physical property. After precise determination, its melting point is roughly in a specific temperature range, which can be used as an important basis for purity determination and identification. The accurate determination of melting point is of great significance for the control of the conditions of synthesis and application of this compound.
    In terms of solubility, (R ) - ( + ) -α - methyl-4-pyridylmethanol exhibits specific solubility characteristics in common organic solvents. In some polar organic solvents, such as methanol and ethanol, it has good solubility. This property allows it to flexibly select suitable solvents according to the difference in solubility in the process of solution reaction, separation and purification, and preparation to achieve the desired chemical purpose.
    In addition, the physical properties such as density and boiling point of the compound also have a great influence on its application in chemical production and laboratory research. Density is related to its distribution and behavior in mixed systems, and boiling point is an important reference index in separation operations such as distillation and rectification.
    In summary, the various physical properties of (R ) - ( + ) -α - methyl-4-pyridylmethanol are related to each other and jointly determine its application and value in many fields such as organic synthesis and medicinal chemistry. Accurate grasp and in-depth study of its physical properties is an important cornerstone for the development of related fields.
    (R) - (+) In what areas is -alpha-Methyl-4-pyridinemethanol applied?
    (R ) - (+) -α - methyl-4-pyridyl methanol, which is useful in many fields.
    In the field of medicine, its value is quite high. Gain has a unique chemical structure and properties, or can be used as a key intermediate to synthesize drugs for the treatment of specific diseases. For example, for some neurological diseases, it can be used as a starting material through delicate chemical reaction steps to prepare drugs that regulate neurotransmitters and improve neurological function. In addition, in the development of cardiovascular diseases drugs, it may also play an important role in the synthesis of drugs with the effect of regulating blood pressure and blood lipids.
    In the field of materials science, it also has considerable applications. Due to its chemical activity, it may be able to participate in the synthesis of polymer materials. With the help of appropriate reaction conditions, it can be introduced into the main chain or side chain of the polymer to give the material new characteristics. For example, improving the hydrophilicity and biocompatibility of the material, so that the material can be used in the field of biomedical materials, such as tissue engineering scaffolds, drug slow-release carriers, etc., have better performance.
    In the field of organic synthetic chemistry, (R ) - (+) -α - methyl-4-pyridyl methanol is an extremely important reagent. Chemists can use its special functional groups to carry out various organic reactions, such as oxidation, reduction, substitution, etc. With these reactions, complex organic molecular structures can be constructed, providing an effective way for the synthesis of new organic compounds, greatly enriching the variety of organic compounds, and promoting the continuous development of organic chemistry.
    What are the synthesis methods of (R) - (+) -alpha-Methyl-4-pyridinemethanol?
    (R ) - (+) - α - Methyl-4-pyridine methanol synthesis method, through the ages, all kinds of ways have their own advantages.
    First, it can be started from the corresponding pyridine derivatives. Pyridine with a specific substituent is used as raw material, through halogenation reaction, a halogen atom is introduced into a specific position of the pyridine ring. This halogen atom seems to open the door to subsequent reactions. Then, it is cleverly combined with metal-organic reagents, such as Grignard reagent or organolithium reagent. Grignard reagent meets halogenated pyridine derivatives due to its reactivity. Under suitable reaction conditions, such as inert gas atmosphere and precisely regulated temperature, the two embrace nucleophilic substitution, and successfully connect methyl-containing groups on the pyridine ring, which is like adding a key side chain to the pyridine skeleton.
    Furthermore, the reduction reaction is also an important path. Select a suitable pyridine aldehyde derivative, the aldehyde group is like the active focus of the reaction. Strong reducing agents such as sodium borohydride and lithium aluminum hydride are mixed in alcoholic solvents such as methanol and ethanol. Sodium borohydride or lithium aluminum hydride generously give electrons to gradually reduce the aldehyde group to an alcohol hydroxyl group, just like a gentle touch, accurately shaping the prototype of α-methyl-4-pyridyl methanol, and under suitable conditions, the three-dimensional configuration of the product can be effectively controlled to obtain (R ) - (+) - isomer.
    In addition, the method of catalytic asymmetric synthesis cannot be ignored. The delicate combination of chiral ligands and metal catalysts constitutes a unique selective catalytic system. In the reaction involving specific reaction substrates, the chiral ligand is like a precise helmsman, guiding the reaction in the direction of generating (R ) - (+) - α - methyl-4-pyridylmethanol. Although this method is delicate and complex, it has unique advantages in the stereochemical control of the product and can be a powerful tool for synthesis.
    These several synthesis methods have their own strengths. They can be used to obtain (R ) - (+) - α - methyl-4-pyridylmethanol depending on factors such as specific needs, availability of raw materials, and reaction conditions.
    (R) - (+) What is the market outlook for -alpha-Methyl-4-pyridinemethanol?
    (R ) - ( + ) -α - methyl-4-pyridylmethanol, an organic compound, has potential uses in medicine, chemical industry and other fields.
    In the field of medicine, such compounds containing pyridine structure are often used as intermediates in drug synthesis. Due to its unique chemical structure and activity, it may participate in the construction of molecules with specific pharmacological activities. With the increasing exploration of novel structures and targets in pharmaceutical research and development, it may emerge as a basic structural unit in the process of innovative drug development. Today's innovative drug research and development competition is fierce, and the demand for characteristic intermediates is increasing, so (R ) - ( + ) -α - methyl-4-pyridylmethanol may have development opportunities in the pharmaceutical intermediates market.
    In the chemical industry, it can be used as organic synthesis raw materials and participate in the preparation of various fine chemicals. With the pursuit of product refinement and high value-added in the chemical industry, the demand for characteristic raw materials in fine chemical synthesis is also growing. The chemical industry pays attention to green and efficient synthesis paths. If a green and efficient synthesis process is developed for (R ) - ( + ) -α - methyl-4-pyridylmethanol, it will conform to the development trend of the industry and open up a broad market space.
    However, its market also has challenges. The synthesis process may be complex and costly, which hinders large-scale production and marketing activities. And the market competition is fierce, and it is necessary to continuously optimize the process and reduce costs in order to gain a place in the market.
    Overall, the (R ) - ( + ) -α - methyl-4-pyridylmethanol market has opportunities and challenges, and with technological progress and market development, it may play a more important role in related fields.