R 1 Benzyl 3 Hydroxyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

(R)-1-Benzyl-3-hydroxyl-pyridine

    Specifications

    HS Code

    420699

    Chemical Formula C13H13NO
    Molecular Weight 199.25
    Appearance Solid (predicted)
    Solubility In Water Low solubility (predicted)
    Solubility In Organic Solvents Soluble in common organic solvents (predicted)
    Logp Predicted value, relevant to lipophilicity
    Chirality Chiral, has (R)-configuration
    Vapor Pressure Low (predicted)

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    General Information
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    Frequently Asked Questions

    As a leading (R)-1-Benzyl-3-hydroxyl-pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of -1-Benzyl-3-hydroxyl-pyridine?
    (R) -1-benzyl-3-hydroxypyridine, which is one of the organic compounds. Its chemical structure is based on a pyridine ring, which is a six-membered nitrogen-containing heterocycle and has aromatic properties. At position 3 of the pyridine ring, there is a hydroxyl group (-OH), which is hydrophilic and has a great influence on the physical and chemical properties of the compound. It can participate in many chemical reactions, such as esterification and ether formation. At the No. 1 position of the pyridine ring, the benzyl group is connected to the benzyl group (CH 2O Ph). The benzene ring part in the benzyl group is also aromatic, which increases the conjugate system of the molecule, enhances the stability of the compound, and also has a significant effect on the spatial structure and electron cloud distribution of the molecule. Due to its unique structure, (R) -1 -benzyl-3-hydroxypyridine is often used as a key intermediate in the field of organic synthesis. It can be transformed into organic compounds with more complex structures and functions through specific chemical reaction pathways. It has important research and application value in many disciplines such as medicinal chemistry and materials science.
    (R) What are the main physical properties of -1-Benzyl-3-hydroxyl-pyridine?
    (R) -1-benzyl-3-hydroxypyridine, this is an organic compound. Its main physical properties are as follows:
    Under normal temperature and pressure, (R) -1-benzyl-3-hydroxypyridine is mostly in a solid state, and the quality is relatively stable.
    When it comes to melting point, this compound has a specific melting point value, but the melting point may fluctuate depending on the preparation process and purity. Generally speaking, its melting point is in a certain range. This property is crucial for the identification and purification of compounds. Melting point measurement can be used to test its purity.
    As for solubility, (R) -1-benzyl-3-hydroxypyridine exhibits certain solubility characteristics in organic solvents. Common organic solvents such as ethanol and ether can be moderately dissolved due to the specific interaction between the molecular structure of the compound and the molecules of the organic solvent. In water, its solubility is relatively limited due to the poor matching of molecular polarity with water.
    Looking at its density, (R) -1-benzyl-3-hydroxypyridine has a specific density value. Although it varies slightly with temperature and pressure, under normal conditions, the density value is relatively fixed. This density parameter is of great significance in chemical production and related experimental operations, such as material ratio and separation process.
    (R) -1-benzyl-3-hydroxypyridine's physical properties have laid a solid foundation for its application in many fields such as organic synthesis and medicinal chemistry. According to its characteristics, researchers can rationally plan experiments and production processes.
    (R) Areas in which -1-Benzyl-3-hydroxyl-pyridine is applied
    (R) -1-benzyl-3-hydroxypyridine is useful in various fields.
    In the field of medicine, it can be a key raw material for the creation of new drugs. Due to its unique chemical structure, it may interact with specific targets in organisms, thus showing the potential to treat diseases. For example, it may be able to play a therapeutic role in some chronic diseases such as inflammatory diseases and neurodegenerative diseases by modulating specific cell signaling pathways.
    In the field of materials science, (R) -1-benzyl-3-hydroxypyridine can also be used. Using it as a starting material, through specific chemical reactions, functional materials with special properties may be prepared. For example, adsorption materials with high selective adsorption capacity for specific substances can be prepared, which can be used for the removal of environmental pollutants, or for the separation and purification of specific compounds in chemical production.
    Furthermore, in the field of organic synthetic chemistry, this compound is an important synthetic building block. Because of the functional groups such as hydroxyl and benzyl contained in the molecule, it can participate in various classical organic reactions, such as nucleophilic substitution, oxidation and reduction, etc., to construct more complex and functional organic molecules, providing a powerful tool for organic synthesis chemists to explore the relationship between the structure and properties of new organic compounds.
    (R) What are the synthetic methods of -1-Benzyl-3-hydroxyl-pyridine
    To prepare (R) -1-benzyl-3-hydroxypyridine, there are many methods, each with its own advantages and disadvantages, and choose the best one to use.
    One can start from the substrate containing the pyridine structure. Starting with a specific pyridine derivative, the chiral center is introduced through the action of a specific chiral reagent, and then under appropriate conditions, the hydroxyl group is introduced at the 3rd position of the pyridine ring, and the benzyl group is connected at the 1st position. In this process, the selection of chiral reagents is crucial, which is related to the optical purity of the product. Select a good chiral reagent, and according to precise operation, a high-purity target product may be obtained. < Br >
    Second, benzyl halide and hydroxypyridine derivatives can also be used as raw materials. First, benzyl halide and pyridine derivatives react in the presence of a specific base and catalyst to form 1-benzylpyridine intermediates, and then under suitable conditions, the 3-position of the intermediate is hydroxylated. This approach requires controlling the reaction conditions, such as temperature, amount of base, and catalyst activity, to ensure that the reaction proceeds in the desired direction and avoid side reactions.
    Third, the method of transition metal catalysis can also be used. Choose suitable transition metal catalysts, such as palladium, rhodium, etc., and cooperate with specific ligands to catalyze the reaction of pyridine-containing substrates with benzylating reagents and hydroxylating reagents. This method requires the optimization of catalysts and ligands to improve the selectivity and efficiency of the reaction.
    All methods require the experimenter to carefully consider and select according to their own conditions, such as the availability of raw materials, the condition of equipment and the degree of technical proficiency, etc., to achieve the purpose of preparing (R) -1-benzyl-3-hydroxypyridine.
    (R) -1-Benzyl-3-hydroxyl-pyridine market prospects
    Nowadays, there are (R) -1-benzyl-3-hydroxypyridine, and its market prospect is quite promising. Due to the field of medicinal chemistry, such compounds are often key intermediates and play an important role in the process of drug development.
    With the development of modern medicine, there is a growing demand for new effective drugs. (R) -1-benzyl-3-hydroxypyridine can respond to a variety of diseases due to its unique chemical structure and can be derived from many bioactive compounds, such as inflammation and tumors. In the creation of inflammatory treatment drugs, it may help to develop more targeted drugs with less side effects, so it is favored by pharmaceutical companies, which is expected to lead to many new drug achievements and expand the pharmaceutical market.
    Furthermore, the field of materials science is also paying attention to such compounds. It may be specially treated and applied to the preparation of functional materials, such as materials with special optical and electrical properties. With the advancement of science and technology, the demand for advanced functional materials is increasing, and the potential application of (R) -1-benzyl-3-hydroxypyridine in this field will open up new market space for it.
    However, its market development is not smooth sailing. The complexity of the synthesis process affects the production cost and yield. If the synthesis technology is not effectively optimized, the high cost will limit its large-scale production and wide application. And the market competition is fierce, and similar or alternative compounds are also competing for share. To take the lead in the market, enterprises and scientific research institutions need to work together to overcome technical problems and enhance product competitiveness.
    Overall, (R) -1-benzyl-3-hydroxypyridine faces challenges, but with its potential value in the field of medicine and materials, the market prospect is still broad. Over time, it will surely shine and inject strong impetus into the development of related industries.