Pyridine, 5-bromo-2-(chloromethyl)-

5 - bromo - 2 - (chloromethyl) - Pyridine is an organic compound with a wide range of uses. In the field of medicinal chemistry, this compound is a key intermediate. The unique structure of the geinpyridine ring and the activity of the halogen atom enable it to participate in many organic synthesis reactions and help build molecular structures with specific biological activities. For example, when creating antibacterial drugs, it can be combined with other functional groups through a series of reactions to develop new antibacterial agents to deal with various bacterial infections.
In the field of materials science, this compound also has outstanding performance. It can participate in polymerization reactions to generate polymer materials with special properties. For example, through carefully designed reaction conditions and comonomers, polymers with good photoelectric properties can be prepared, which is expected to be used in optoelectronic devices such as organic Light Emitting Diodes (OLEDs) to improve the luminous efficiency and stability of such devices.
Furthermore, in the field of pesticide chemistry, 5-bromo-2 - (chloromethyl) - Pyridine also plays an important role. With its structural properties, it can be used to synthesize pesticides with high insecticidal and bactericidal properties. It can interfere with the physiological and metabolic processes of pests or pathogens, achieve the purpose of controlling pests and diseases, and thus escort the harvest of agricultural production.
In summary, 5-bromo-2 - (chloromethyl) - Pyridine has shown important application value in many fields such as medicine, materials, and pesticides due to its unique chemical structure, and has made great contributions to promoting scientific research and technological development in various fields.

5 - bromo - 2 - (chloromethyl) - Pyridine is an organic compound. Its physical properties are as follows:
This substance is usually in a solid or liquid state, but the exact physical form will change depending on environmental conditions. Looking at its appearance, it is usually colorless to pale yellow, and may change color slightly under the action of light and air.
When it comes to the melting point, the literature shows that it is about [X] ° C, which is the critical temperature for the substance to melt from a solid state to a liquid state. The melting point is affected by factors such as crystal form and purity, and the melting point of high-purity samples is relatively stable and close to the theoretical value.
In terms of boiling point, it is roughly [X] ° C. When the temperature reaches this point, the substance changes from a liquid state to a gaseous state. The boiling point is closely related to the external pressure. Generally, the value under standard atmospheric pressure shall prevail. When the pressure changes, the boiling point also changes accordingly.
In terms of solubility, it has good solubility in organic solvents such as dichloromethane, chloroform, toluene, etc. Because the structure of the compound contains hydrophobic groups, and there are van der Waals forces and other interactions between organic solvent molecules, it can be miscible. However, in water, it has poor solubility. Due to its strong structural hydrophobicity and weak interaction with water molecules, it is difficult to form a homogeneous system with water.
The density is about [X] g/cm ³, which characterizes the mass of matter per unit volume. It is of great significance for material measurement and reaction system design in the fields of chemical industry and scientific research. The vapor pressure of
5 - bromo - 2 - (chloromethyl) - Pyridine is low, and at room temperature and pressure, it volatilizes to a small vapor phase tendency. Vapor pressure is closely related to temperature, and when temperature increases, vapor pressure increases.

5 - bromo - 2 - (chloromethyl) - Pyridine is an organic compound, and its chemical stability is quite complex. Let me explain in detail.
From the perspective of structure, this compound contains bromine atoms, chloromethyl groups and pyridine rings. Pyridine rings are aromatic, and their electron cloud distribution is special, which endows the compound with certain stability. However, the existence of bromine atoms and chloromethyl groups adds variables to its chemical properties.
The activity of bromine atoms is not low, and under appropriate conditions, nucleophilic substitution reactions can occur. When encountering nucleophilic reagents, bromine ions are easy to leave and are replaced by nucleophilic groups. This is because the bromine-carbon bond has a certain polarity, and the carbon is partially positively charged, which is easy to be attacked by nucleophilic reagents.
The chlorine atoms in chloromethyl are also active. Chloromethyl can participate in a variety of reactions, such as reacting with nucleophiles to form new carbon-heteroatomic bonds. And chloromethyl is affected by the pyridine ring, and its activity may be changed. The electronic effect of the pyridine ring can change the electron cloud density on chloromethyl carbon, which affects the reactivity.
In terms of stability, if there is no reagent to initiate the reaction in the environment, this compound is relatively stable under normal temperature, pressure, dark and dry conditions. However, in the case of nucleophiles, high temperature, light and other conditions, the stability is greatly reduced and the reaction is prone to occur. For example, at high temperature, bromine atoms and chloromethyl are more likely to leave, triggering various reactions.
In summary, the chemical stability of 5-bromo-2- (chloromethyl) -Pyridine varies according to environmental conditions and the reagents encountered. It can remain relatively stable under certain mild conditions, but it is prone to chemical reactions under active reaction conditions.

The production process of 5-bromo-2- (chloromethyl) pyridine is like the ancient alchemy technique, and all aspects need to be carefully controlled.
The choice of starting materials is crucial. Often based on specific pyridine derivatives, just like the selection of alchemy materials needs to be accurate. If a pyridine compound containing suitable substituents is selected, it will lay the foundation for subsequent reactions.
Halogenation is a key step. To introduce bromine atoms, brominating reagents can be used, such as liquid bromine, N-bromosuccinimide (NBS), etc. The reaction conditions need to be carefully controlled, and the choice of temperature and solvent will affect the reaction trend. If NBS is used as a brominating agent, in a suitable organic solvent such as carbon tetrachloride, under the action of an initiator, such as benzoyl peroxide, the reaction is initiated by heating, just like the heat of alchemy, and the ideal bromide product can be obtained.
The step of introducing chloromethyl should not be underestimated. Chloromethylation reagents such as chloromethyl ether, triformaldehyde and hydrogen chloride are often used. The pH and reaction time of the reaction system need to be strictly controlled. Taking chloromethyl methyl ether as an example, in the presence of a catalyst such as anhydrous zinc chloride, it reacts with the aforementioned bromide products and precisely adjusts the reaction conditions, so that chloromethyl can be successfully connected, just like the preparation of alchemy, the difference is thousands of miles.
The reaction is over, and the separation and purification of the product is also a priority. Recrystallization, column chromatography, etc. can be used. Recrystallization requires the selection of a suitable solvent to dissolve and crystallize the product in it, and remove impurities; column chromatography is based on the difference between the adsorption of the product and the impurity, with a suitable eluent separation, just like the ancient method of purifying medicinal pills, removing voids and storing cyanine, to obtain a pure 5-bromo-2 - (chloromethyl) pyridine product.

5-Bromo-2 - (chloromethyl) pyridine is difficult to determine in the market price range. Because the market price is often influenced by many factors, it is like a changing situation and cannot be determined drastically.
First, the price of raw materials has a great impact on it. If raw materials are easy to obtain and cheap, the cost of the product will decrease, and the price may decrease; conversely, if raw materials are scarce and expensive, the price of the product will rise. Second, the preparation process is complicated and simple, which is also related to cost and price. The subtle and simple method can reduce energy consumption, save labor hours, and reduce costs, which will affect the price; the complicated and difficult process is the opposite.
Third, the market supply and demand situation is the key factor. If the demand is strong and the supply is scarce, the price will rise; if the demand is weak and the supply is excessive, the price will fall. Fourth, the manufacturers are different, and their pricing strategies are also different. Large factories have low costs or competitive prices due to scale effects; small factories or cost considerations, pricing is different.
In addition, regional differences, transportation costs, policies and regulations, etc., can all have an invisible impact on the market price of the product. Therefore, in order to determine its market price range, it is necessary to carefully examine various factors such as the raw material market, process progress, supply and demand conditions, and manufacturer strategies, and comprehensively weigh them to obtain a more accurate judgment. However, it is ultimately difficult to explain its specific price range.