Pyridine 5 Bromo 2 4 Dichloro
pyridine pyrrole pyrazine piperidine piperazine

Pyridine, 5-bromo-2,4-dichloro-

    Specifications

    HS Code

    637149

    Chemical Formula C5H2BrCl2N
    Molar Mass 238.887 g/mol
    Appearance Solid (predicted)
    Boiling Point Approx. 267 - 269 °C (predicted)
    Melting Point 62 - 64 °C
    Density 1.924 g/cm³ (predicted)
    Water Solubility Insoluble (predicted)
    Logp 3.93 (predicted)
    Vapor Pressure Very low (predicted)
    Flash Point 115.6 °C (predicted)

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    General Information
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    Frequently Asked Questions

    As a leading Pyridine, 5-bromo-2,4-dichloro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 5-bromo-2,4-dichloropyridine?
    5-Bromo-2,4-dinitrotoluene is an organic compound with unique chemical properties.
    Looking at its structure, the bromine atom is connected to the dinitro group on the toluene. Due to the strong electron-absorbing properties of the nitro group, this compound has high chemical activity. Nitro can reduce the electron cloud density of the benzene ring, making the benzene ring more susceptible to nucleophilic substitution reactions. For example, with appropriate nucleophilic reagents, bromine atoms can be replaced by nucleophilic groups.
    Furthermore, in 5-bromo-2,4-dinitrotoluene, bromine atoms are also active check points. Under specific reaction conditions, bromine atomic energy participates in many reactions, such as the common substitution and elimination of halogenated hydrocarbons.
    This compound has certain oxidation properties due to its nitro group. Under certain conditions, the nitro group can be reduced and converted into other groups such as amino groups, which is of great significance in the field of organic synthesis and can provide an effective path for the preparation of various nitrogen-containing compounds.
    In addition, 5-bromo-2,4-dinitrotoluene usually has a certain solubility in organic solvents, which helps it participate in chemical reactions in solution. However, it should be noted that it has certain toxicity and danger. During operation and use, it is necessary to follow strict safety regulations and take protective measures to prevent harm to human body and the environment.
    What are the physical properties of 5-bromo-2,4-dichloropyridine?
    5-% cyanogen-2,4-difluoropyridine is an organic compound, and its physical properties are as follows:
    Viewed, this substance is mostly colorless to light yellow liquid at room temperature, with a clear appearance and no impurities visible to the naked eye.
    It has a special odor, although it is not pungent or intolerable, it is also clearly identifiable.
    When it comes to boiling point, it is about a specific temperature range. This property makes it change from liquid to gaseous under the corresponding thermal environment. The value of its boiling point is the result of the comprehensive action of many factors such as the intermolecular force of the substance itself. It is crucial in chemical production, separation and purification processes, and is related to the precise control of operating temperature.
    Melting point also has a specific value. Melting point characterizes the critical temperature at which a substance melts from a solid state to a liquid state. The melting point of 5-% cyanogen-2,4-difluoropyridine determines the low temperature under which it survives as a solid state, and above this temperature it gradually melts into a liquid state. This property is of great significance for the ambient temperature setting of storage, transportation and related processing processes.
    In terms of solubility, it exhibits certain solubility characteristics in organic solvents. It can be soluble in some common organic solvents, such as ethanol, acetone, etc., because the molecules of the substance and the solvent molecules can form suitable interactions, such as van der Waals forces, hydrogen bonds, etc. In water, its solubility is relatively limited. This difference is due to the difference in the degree of matching between the polarity of the substance molecule and the polarity of the water molecule. This solubility characteristic has a great impact on its reaction, separation and application scenarios in different media.
    Density is also one of its important physical properties. The specific density value reflects the quality of the substance in a unit volume. It is an indispensable parameter in chemical operations related to metrology, mixing and hydrodynamics. It is related to the accuracy of the material ratio and the stability of the reaction system.
    What are the main applications of 5-bromo-2,4-dichloropyridine?
    5-Bromo-2,4-difluoroaniline is an important organic compound, and its main application fields are as follows:
    1. ** Medicinal Chemistry **: In the field of creating new antimicrobial drugs, 5-bromo-2,4-difluoroaniline can be used as a key intermediate. By chemical modification, it can be constructed into the molecular structure of the drug to give the drug specific antimicrobial activity. For example, the development of some antimicrobial agents against drug-resistant bacteria takes advantage of the unique structure of the compound to enhance the binding ability of the drug to the bacterial target, thereby enhancing the antibacterial effect. In the development of anti-cancer drugs, researchers have found that the structure of 5-bromo-2,4-difluoroaniline can be cleverly designed to enable the drug to act more precisely on specific molecular targets of cancer cells, such as protein kinases involved in cancer cell proliferation signaling pathways. By inhibiting the activity of these targets, the growth and spread of cancer cells can be effectively inhibited.
    2. ** Pesticide field **: In the creation of new pesticides, 5-bromo-2,4-difluoroaniline plays an indispensable role. It can be introduced into pesticide molecules to enhance the interference of pesticides on the nervous system or other physiological functions of pests. For example, it can block the nerve transmission of pests, causing them to have dysfunction, difficulty eating, and eventually death. In the research and development of herbicides, this compound can be used as a key structural unit to design herbicides with a highly selective inhibitory effect on specific weeds. By interacting with specific enzymes or metabolic pathways in weeds, weed growth is inhibited, but the effect on crops is minimal, ensuring the efficiency and safety of agricultural production.
    3. ** Materials Science **: In the preparation of organic optoelectronic materials, 5-bromo-2,4-difluoroaniline can be used to synthesize polymers or small molecule materials with special optoelectronic properties. These materials have shown potential application value in the fields of organic Light Emitting Diode (OLED), organic solar cells, etc. For example, in OLED, it can be used as part of the light-emitting layer material to adjust the luminous color and efficiency of the material. In the development of functional coatings, the addition of compounds derived from 5-bromo-2,4-difluoroaniline can impart special properties to the coatings, such as enhancing their corrosion resistance, wear resistance, or adsorption to specific substances, expanding the application range of coatings in industries, buildings, and other fields.
    What are the synthesis methods of 5-bromo-2,4-dichloropyridine?
    There are several methods for the synthesis of 5-bromo-2,4-dinitrotoluene in ancient times. First, toluene is used as the starting material, and it has undergone the steps of nitrification and bromination.
    Take toluene first, place it in an appropriate reactor, and use the mixed acid of concentrated nitric acid and concentrated sulfuric acid as the nitrifying reagent. The two are prepared in a certain proportion and slowly added to the toluene. At the same time, the temperature should be carefully controlled to prevent the reaction from being too violent. This nitrification reaction can introduce nitro groups into the benzene ring of toluene to generate 2,4-dinitrotoluene. In this step, attention should be paid to the concentration and dosage of mixed acid, as well as the control of reaction temperature and time, in order to obtain a higher yield product.
    Next, the obtained 2,4-dinitrotoluene is put into the bromination reaction system. Liquid bromine is used as the brominating agent, supplemented by appropriate catalysts, such as iron powder or iron tribromide. Under suitable reaction conditions, liquid bromine undergoes a substitution reaction with 2,4-dinitrotoluene, and bromine atoms are introduced at specific positions in its benzene ring to obtain 5-bromo-2,4-dinitrotoluene. In this bromination process, the amount of catalyst, reaction temperature and time also have a significant impact on the purity and yield of the product.
    Another method is to use p-nitrotoluene as the starting material. Brominate it first, and then nitrate it. Under suitable conditions, the brominated reaction of p-nitrotoluene and bromine on the benzene ring is realized by the action of a catalyst to generate brominated p-nitrotoluene. Then, the brominated product is placed in a nitrification system and nitrified with mixed acids, so that the nitro group is introduced at another position of the benzene ring, and the final product is 5-bromo-2,4-dinitrotoluene. In this path, the optimization of the conditions of the two reactions, such as the ratio of reactants, temperature, time and other factors, are the keys to the successful synthesis.
    What should be paid attention to when storing and transporting 5-bromo-2,4-dichloropyridine?
    For 5-2,4-dinitrobenzoic acid, please pay attention to the following things when it is stored and damaged.
    This chemical substance has a certain chemical activity, and its storage environment is of paramount importance. If it is exposed to open flames, high temperature, it may cause ignition or even explosion. And it is necessary to avoid the combination of oxidation and raw materials to prevent the occurrence of intense chemical reactions. When the two meet, it may lead to out-of-control reactions and endanger safety.
    Furthermore, the packaging should not be ignored. It must be stored in a packaging container for use, which is dense and firm to prevent its leakage. On the container, clearly indicate its dangerous characteristics, warnings, etc., so that the recipient can see at a glance where the danger is. In the event of a leak, it is also necessary to identify the location and personnel of the pick-up tool. People need to be trained, familiar with the characteristics of this chemical product and emergency management methods. On the way, we should abide by the regulations of the relevant traffic and dangerous chemical products, and prevent accidents such as collisions and collapses.
    In addition, in the event of accidents such as possible leakage, a comprehensive emergency case is required. Once there is a leak, immediately isolate the pollution and restrict the entry and exit of people. Emergency managers should wear protective equipment and do not expose themselves to danger. A small amount of leakage can be collected in containers that are dry, dry, and damaged; a large amount of leakage can be contained in embankments or pits, covered with inert materials such as sand and lime, and then properly treated.